ABSTRACT
A phytochemical investigation of an ethanolic extract of the leaves of Curatella americana Linn. (Dilleniaceae) resulted in the isolation and identification of the flavonol glycoside avicularin and gallic acid.
Subject(s)
Plants, Medicinal/analysis , Acetates/isolation & purification , Chromatography , Gallic Acid/isolation & purification , Hydrolysis , Magnetic Resonance Spectroscopy , Mexico , Quercetin/isolation & purificationABSTRACT
A phytochemical investigation of an ethanolic extract of the whole plant of Echites hirsuta (Apocynaceae) resulted in the isolation and identification of the flavonoids naringenin, aromadendrin (dihydrokaempferol), and kaempferol; the coumarin fraxetin; the triterpene ursolic acid; and the sterol glycoside sitosteryl glucoside.
Subject(s)
Plants/analysis , Chromatography, Gel , Coumarins/isolation & purification , Flavonoids/isolation & purification , Glucosides/isolation & purification , Mass Spectrometry , Methods , Sitosterols/isolation & purification , Triterpenes/isolation & purificationABSTRACT
One hundred and seventy-seven plant extracts, representing 163 species of plants and/or fungi, were evaluated in rats to determine their antiinflammatory activity using the carrageenin-induced pedal edema assay. Of the 163 species of plants and/or fungi tested, 17 exhibited between 30--39 per cent inhibition of inflammation, 21 between 40-49 per cent, 15 between 50--59 per cent, four between 60--69 per cent, and two gave greater than 70 per cent inhibition of carrageenin-induced pedal edema.
Subject(s)
Anti-Inflammatory Agents/therapeutic use , Edema/prevention & control , Plant Extracts/therapeutic use , Plants, Medicinal , Animals , Carrageenan , Edema/chemically induced , Foot , Helianthus , Hindlimb , Male , Plants, Toxic , Podophyllum , Rats , Species SpecificityABSTRACT
In a continuing effort to study thoroughly the alkaloids of Catharanthus roseus, new dimeric alkaloids were isolated and characterized. Structures are proposed for leurocolombine and vinamidine based on UV, IR, PMR, high-resolution mass spectrometry, and CMR. Pseudovincaleukoblastine diol was identified by PMR and mass spectrometry. Leurocolombine exhibited antimitotic activity and marginal antitumor activity against the Ridgeway osteogenic sarcoma.