ABSTRACT
OBJECTIVE: To report the clinical profile and drug sensitivity patterns in Citrobacter endophthalmitis. DESIGN: Retrospective interventional case series. METHODS: Retrospective analysis of all the cases of Citrobacter endophthalmitis presenting to a tertiary referral ophthalmic centre in eastern India from January 2009 to December 2011 was done. RESULTS: Five cases were included in the study. Of these 5, 1 was posttraumatic, 1 was of endogenous origin, and the rest were postoperative. Vitreous surgery was done for 3 cases, whereas 1 patient declined surgery. The endogenous case received only intravitreal antibiotics. All isolates were sensitive to ciprofloxacin. Only 1 of the 5 isolates was sensitive to ceftazidime. Only 1 eye achieved a final visual acuity of 20/60 and the rest became phthisical at final follow-up. CONCLUSIONS: Citrobacter is a rare cause of endophthalmitis with poor outcome. Ciprofloxacin should be considered as the first line of treatment.
Subject(s)
Citrobacter/isolation & purification , Endophthalmitis/microbiology , Enterobacteriaceae Infections/microbiology , Eye Infections, Bacterial/microbiology , Aged , Anti-Bacterial Agents/therapeutic use , Child , Ciprofloxacin/therapeutic use , Endophthalmitis/diagnosis , Endophthalmitis/drug therapy , Enterobacteriaceae Infections/diagnosis , Enterobacteriaceae Infections/drug therapy , Eye Infections, Bacterial/diagnosis , Eye Infections, Bacterial/drug therapy , Female , Follow-Up Studies , Humans , Intravitreal Injections , Male , Microbial Sensitivity Tests , Middle Aged , Retrospective Studies , Visual Acuity/physiology , VitrectomyABSTRACT
The purpose of this study is to describe the correlation of findings between results from spectral domain optical coherence tomography (SD-OCT) and microperimetry in a case series regarding patients with Goldmann-Favre syndrome. Goldmann-Favre syndrome is a rare autosomal recessive hereditary vitreo-retinal degeneration that impacts the functionality of vision in subjects. Three men with this condition were assessed and subjected to microperimetry and SD-OCT. Two of the men were brothers. This study finds that the retinoschisis and macular cystoid changes noted in the SD-OCT matched the scotomas revealed by the microperimetry. The findings of each of the individual cases are reported herein.
