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1.
Int Arch Otorhinolaryngol ; 28(3): e487-e491, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38974631

ABSTRACT

Introduction Adenoidectomy is one of the most common procedures performed by otolaryngologists. Traditional adenoid curettage is performed blindly, which can result in inadequate removal of the adenoid and injury to the surrounding structures. Objective To perform transnasal endoscopic examinations to assess the nasopharynx after conventional curettage adenoidectomy. Methods The present prospective study included 100 children with a mean age of 4.2 ± 3.07 years. It is composed of two steps: conventional curettage adenoidectomy by a resident trainee; and endoscopic evaluation of the nasopharynx through a 0° telescope to assess adenoidal remnants, injury to the surgical field or adjacent structures, and bleeding points. Results Adenoid remnants were observed in 42% of the cases after conventional adenoid curettage in multiple locations, such as the roof of the nasopharynx over the choana (24%), the tubal tonsil (12%), the posterior pharyngeal wall (4%), and the posterior end of the nasal septum (2%). Injury to the surgical field and adjacent structures was observed in 46% of the cases (posterior pharyngeal wall: 23%; lateral pharyngeal wall: 11%; Passavant ridge: 10%; and the Eustachian tube orifice: 2%). Endoscopic bleeding was observed in 29% of the cases; 13% of the cases were from adenoid remnants, 10%, from the mucosa, and 6%, from the pharyngeal muscles. Bleeding was mild in 19% of the cases, moderate in 9%, and severe in 1%. Conclusion Endoscopic evaluation of the nasopharynx following conventional adenoid curettage provides important data regarding adenoid remnants, injury to the surgical field or nearby structures, and bleeding points, which aids in the provision of optimal care and in the achievement of a better outcome.

2.
Clin Otolaryngol ; 49(4): 512-517, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38606721

ABSTRACT

INTRODUCTION: To assess the usage of contralateral infrahyoid muscles as onlay flap in prevention of pharyngo-cutaneous fistula (PCF) in total laryngectomy (TL) patients with high risk factors of PCF development. METHODS: This study included 10 patients who suffered from advanced laryngeal carcinoma with presence of risk factors for development of PCF. We added an enforcement muscular layer during neo-pharynx wall repair, the infrahyoid muscle flap of the contralateral side of the tumour origin as an onlay muscular flap to cover the anastomotic site for healing augmentation. Patients were followed up for PCF development where the PCF incidence was calculated. RESULTS: One patient died from congestive heart failure in the 21th post-operative day so, the actual PCF rate in TL patients with high risk factors of PCF development in our study was 11.11% (1 out of 9 cases). CONCLUSIONS: Infrahyoid muscle flap may have a role in preventing PCF after TL in patients with high risk factors of PCF development in this case series study to be further assessed in other studies to justify its role.


Subject(s)
Laryngeal Neoplasms , Laryngectomy , Pharyngeal Diseases , Surgical Flaps , Humans , Laryngectomy/methods , Male , Middle Aged , Laryngeal Neoplasms/surgery , Aged , Female , Pharyngeal Diseases/etiology , Pharyngeal Diseases/prevention & control , Cutaneous Fistula/etiology , Cutaneous Fistula/prevention & control , Postoperative Complications/prevention & control , Risk Factors , Plastic Surgery Procedures/methods , Pharynx/surgery
3.
Am J Otolaryngol ; 43(3): 103468, 2022.
Article in English | MEDLINE | ID: mdl-35429850

ABSTRACT

The glossopharyngeal nerve block (GNB) was evaluated for pain control together with the magnitude of obtunded gag reflex as a useful clinical sign of GNB. METHODS: 400 patients scheduled for oropharyngeal surgery were randomly allocated into 2 groups (200 patients in each group), Group1 patients received bilateral GNB with 0.125% bupivacaine, 0.5 xylocaine, and 4 mg dexamethasone, while Group 2 patients were enrolled as a control group. Throat pain was evaluated using the visual analog scale at 0.5, 8, and 24 h after surgery, and the degree of gag reflex response was evaluated at the same time points. RESULTS: Postoperative pain scores at rest and during swallowing were significantly lower in Group 1 versus Group 2. The analgesic efficacy of GNB was intensely interrelated with the magnitude of the obtunded gag reflex (P 0.01). CONCLUSIONS: GNB is beneficial for pain control in oropharyngeal surgery. An obtunded gag reflex could be a useful clinical sign for a successful GNB analgesic outcome.


Subject(s)
Bupivacaine , Nerve Block , Analgesics , Anesthetics, Local , Double-Blind Method , Gagging , Glossopharyngeal Nerve , Humans , Pain Management , Pain, Postoperative/drug therapy , Pain, Postoperative/etiology , Pain, Postoperative/prevention & control
4.
Acad Radiol ; 29(5): 674-684, 2022 05.
Article in English | MEDLINE | ID: mdl-34998684

ABSTRACT

OBJECTIVE: To develop a systematic approach for magnetic resonance imaging (MRI) analysis, imaging spectrum, and classification system for the staging of post-COVID-19 head and neck mucormycosis. METHOD: The study included 63 post-COVID-19 patients with pathologically proven mucormycosis who underwent head and neck MR imaging. Three independent radiologists assessed the imaging spectrum of mucormycosis, MRI characteristics of sino-nasal mucormycosis, and extra-sinus extension, and submitted a final staging using a systematic approach and a proposed categorization system. A consensus reading was considered the reference imaging standard. The kappa statistics were used to assess the categorization system's diagnostic reliability. RESULTS: The overall interreader agreement of the MR staging system was very good (k-score = 0.817). MR imaging spectrum involved localized sino-nasal mucormycosis (n = 7 patients, 11.1%), sino-nasal mucormycosis with maxillo-facial soft tissue extension (n = 28 patients, 44.5 %), sino-nasal mucormycosis with maxillo-facial bony extension (n = 7 patients, 11.1%), sino-naso-orbital mucormycosis (n = 13 patients, 20.6%), and sino-nasal mucormycosis with cranium or intracranial extension (n = 8 patients, 12.7%). Extra-sinus extension to the orbit and brain did not have significant association with involvement of the posterior ethmoid/sphenoid sinuses and maxillo-facial regions (p > 0.05). MRI-based staging involved four stages: stage 1 (n = 7, 11.1%); stage 2 (n = 35, 55.6%), and stage 3 (n = 13, 20.6%), and stage 4 (n = 8, 12.7%). Involvement of the bone and MR-based staging were significant predictors of patients' mortality p = 0.012 and 0.033, respectively. CONCLUSION: This study used a diagnostic-reliable staging method to define the imaging spectrum of post-COVID-19 head and neck mucormycosis and identify risk variables for extra-sinus extension.


Subject(s)
COVID-19 , Mucormycosis , Orbital Diseases , Humans , Magnetic Resonance Imaging , Mucormycosis/diagnostic imaging , Orbital Diseases/diagnosis , Reproducibility of Results
5.
Otolaryngol Head Neck Surg ; 166(2): 399-402, 2022 02.
Article in English | MEDLINE | ID: mdl-33752537

ABSTRACT

This study describes a simple extraendolaryngeal technique to apply laryngeal keel in dealing with anterior commissure web/fibrosis. Standard extraendolaryngeal punctures were applied via 20-gauge needles, 30° from the skin surface, in midline through the cricothyroid and thyrohyoid membranes. These needles were used as a conduit for the passage of 2/0 Prolene threads, which were retrieved through the laryngoscope by crocodile forceps. Both laryngoscopic ends of the Prolene threads were passed through a fabricated silastic sheet (keel stent) via a 22-gauge free needle, and these ends were tied to have a secure internal knot. Steady traction was applied on the other 2 external threads until there was appropriate application of this keel stent within the vicinity of anterior commissure. Finally, these external ends were tied to have a secure external knot. A keel stent could be applied without the need for special instrumentation and with reasonable outcomes (proper healing of anterior commissure, satisfied voice outcome, and patent airway).


Subject(s)
Laryngeal Diseases/surgery , Laryngoscopy , Stents , Child, Preschool , Female , Humans , Infant , Male , Punctures , Suture Techniques
8.
Plast Reconstr Surg Glob Open ; 8(1): e2546, 2020 Jan.
Article in English | MEDLINE | ID: mdl-32095389

ABSTRACT

The fibula free flap (FFF) is regarded as the gold standard in mandibular reconstruction. Dental rehabilitation is important to improve the health-related quality of life of patients undergoing mandibular reconstruction. FFF provides adequate cortical bone osseous tissue for use in dental implantation. The application of "axial split osteotomy" via a double-barrel fibula graft may enable discrepancies between the native mandible and FFF to be avoided, thereby improving the likelihood of early and successful dental rehabilitation.

9.
J Oral Maxillofac Surg ; 78(6): 1035.e1-1035.e6, 2020 06.
Article in English | MEDLINE | ID: mdl-30959007

ABSTRACT

PURPOSE: The cost of computer-aided design and computer-aided manufacturing (CAD-CAM) technology has created obstacles for its widespread use despite its several advantages. This study compared the cost of CAD-CAM technology with that of the conventional freehand technique in fibula reshaping for mandibular reconstruction. MATERIALS AND METHODS: A retrospective comparative study was conducted at the Maxillofacial and Dental Unit of the Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico (Milan, Italy). The study compared 15 patients in the CAD-CAM group with 10 patients in the conventional freehand group. Only benign pathologic lesions that required at least 3 fibular segments for reconstruction were included. The consumption of resources was estimated using micro-costing analysis (activity-based costing approach). RESULTS: The CAD-CAM group included 15 patients (7 men and 8 women) with a mean age of 42.2 ± 1.5 years, and the conventional freehand group included 10 patients (4 men and 6 women) with a mean age of 40.8 ± 0.9 years. Although CAD-CAM was a statistically expensive procedure in the perioperative phase (P < .0001), no significant difference was shown in total health care costs between the 2 groups (P = .98). CONCLUSION: CAD-CAM technology had a comparable expense to the conventional freehand technique, specifically for defects requiring at least 3 fibular segments.


Subject(s)
Free Tissue Flaps , Mandibular Reconstruction , Adult , Computer-Aided Design , Female , Fibula , Humans , Italy , Male , Retrospective Studies
10.
J Craniomaxillofac Surg ; 47(9): 1331-1337, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31331855

ABSTRACT

INTRODUCTION: Although multilevel surgery is the mainstay treatment for severe obstructive sleep apnoea syndrome (OSAS), bi-maxillary surgery (maxillomandibular advancement [MMA]) is the most efficacious single procedure for the expansion of the whole pharyngeal airway. MMA is an alternative to the gold standard of continuous positive airway pressure and is equivalent to tracheotomy. PATIENTS AND METHOD: Computer-aided design/computer-aided manufacturing (CAD-CAM) technology was used to virtually assess the degree of mandibular and/or maxillary advancement and rotation required to obtain adequate posterior airway space (PAS) in eight patients (seven males, one female). The mean age of the patients was 45.5 years (range, 27-51 years), and the average body mass index was 28.9 kg/m2 (range, 21.9-31.8 kg/m2). RESULTS: The study group showed significant mandibular advancement, widening of the PAS, and reduction of the apnoea hypopnea index (p < 0.0001, p < 0.0001, and p < 0.0002, respectively). Moreover, patient satisfaction scores regarding postoperative facial profile changes showed excellent compliance. CONCLUSION: This study demonstrated that bi-maxillary surgery is an efficient single surgical procedure in patients with multilevel OSAS. CAD-CAM technology aided surgeons in performing this operation precisely and enabled patients to expect specific facial profiles.


Subject(s)
Orthognathic Surgery , Sleep Apnea, Obstructive , Adult , Cephalometry , Computer-Aided Design , Female , Humans , Male , Mandibular Advancement , Middle Aged , Patients , Treatment Outcome , Young Adult
11.
Craniomaxillofac Trauma Reconstr ; 11(4): 256-264, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30574268

ABSTRACT

Despite the high frequency of the zygomaticomaxillary complex (ZMC) fractures, there is no consensus among facial reconstructive surgeons regarding the best surgical management; thus, surgical choice for ZMC fractures is still challenging. This study included 40 patients with displaced ZMC fracture. Twenty patients were treated with open reduction and internal fixation (OR/IF) using two-point fixation technique (at infraorbital margin and zygomaticofrontal buttress region) and the remaining 20 patients were treated with OR/IF using three-point fixation technique (at frontozygomatic suture, infraorbital margin, and zygomatico maxillary buttress). The results of both types of ZMC fractures repair were then statistically compared. No statistical differences between the two types regarding malar eminence asymmetry; projection (forward displacement) and width (medial displacement) in axial CT; inferior displacement; superior displacement and width (medial displacement) in coronal CT; angle of displacement (outward displacement) in 3D CT; masseter and temporalis muscles power electromyography; actual duration of surgery; and patient satisfaction. On the other hand, the total cost of the used plates and screws was significantly higher with three-point repair than two-point repair ( p = 0.003). Moreover, postoperative CT lateral zygoma displacement was statistically significantly better in three-point fixation. Two-point fixation modality for displaced ZMC fractures is as effective as three-point method in fixation and prevents postreduction rotation or clinical displacement with significantly lower cost.

12.
Ann Otol Rhinol Laryngol ; 127(9): 598-603, 2018 Sep.
Article in English | MEDLINE | ID: mdl-29952632

ABSTRACT

BACKGROUND: The nasal valve area is the narrowest point in the nasal airway. External nasal valve (ENV) collapse during inspiration occurs if external valve area is too narrow or its lateral component is too floppy. PATIENTS AND METHOD: Twelve patients (7 males, 5 females) aged 8 to 12 years complaining of nasal obstruction due to ENV dysfunction underwent surgical intervention using alar batten graft assisted by temporary external suspensory suture. RESULTS: All patients showed subjective and objective improvement of the nasal airway. The mean Nasal Obstructive Symptom Evaluation (NOSE) was 14 ± 1.71 before surgery and 7.83 ± 1.47 1 year after surgery (significant improvement, p ≤ .0001). The mean Peak Inspiratory Flow Rate was 29.92 ± 4.46 before surgery and 42.58 ± 4.93 1 year after surgery (significant improvement, P ≤ .0001). CONCLUSION: External nasal valve collapse in children can be managed surgically by using alar batten graft. Temporary suspension suture can be helpful for supporting of the graft until complete healing occurs.


Subject(s)
Nasal Cartilages/transplantation , Nasal Cavity/surgery , Nasal Obstruction/surgery , Rhinoplasty/methods , Suture Techniques/instrumentation , Sutures , Child , Female , Follow-Up Studies , Humans , Male , Retrospective Studies , Treatment Outcome
13.
Eur Arch Otorhinolaryngol ; 275(3): 809-813, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29330599

ABSTRACT

OBJECTIVE: The aim of this study was to assess the infraorbital foramen (IOF) using CT in patients with Zygomaticomaxillary complex (ZMC) fractures (midface fracture). PATIENTS AND METHODS: This prospective study was carried out on 49 patients had ZMC fractures (98 sides) and 27 patients (54 sides) with craniomaxillofacial fractures rather than fractured ZMC as a control. Using CT, position of IOF was documented on 3D view in relation to inferior orbital rim, tooth root relation and finally with a novel imaginary line passing between anterior nasal spine and whitnall tubercle. RESULTS: Position of IOF had fixed anatomical landmark: just lateral to a line drawn between the anterior nasal spine to whitnall tubercle (clinically between nasal tip-lateral canthal ligament) and lateral to vertical plane to root of maxillary canine also with variable distance from inferior orbital rim ranged from 4.56 to 18.03 mm with a mean of 7.9 ± 2.447 mm. CONCLUSION: Even though ZMC fractures disturb the anatomical location of the ZMC bones, there are still preserved reliable fixed landmarks maxillofacial surgeons can depend on to identify and preserve ION.


Subject(s)
Anatomic Landmarks/diagnostic imaging , Orbit/diagnostic imaging , Orbital Fractures/diagnostic imaging , Tomography, X-Ray Computed , Zygomatic Fractures/diagnostic imaging , Adolescent , Adult , Female , Fracture Fixation, Internal , Humans , Male , Middle Aged , Orbit/injuries , Orbital Fractures/surgery , Prospective Studies , Young Adult , Zygomatic Fractures/surgery
14.
J Craniofac Surg ; 28(4): 1035-1037, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28328598

ABSTRACT

OBJECTIVE: To describe a relatively simple, easy, and safe technique for open reduction and internal fixation of the mandibular angle fracture using the combined modified percutaneous and oral approach with no special instrumentation. PATIENTS AND METHODS: This study was carried out on 10 patients who had traumatic mandibular angle fractures. All patients were managed by open reduction and internal fixation. Intraoral exposure and reduction of the fracture was performed through the gingivolabial incision. Then, a modified percutaneous-transbuccal way was utilized for conduction of the microdrill shaft and screw driver to permit screws fixation with perpendicular relations between plate and inserted screws. RESULTS: There were no registered soft tissue infections, wound dehiscence, occlusal defects, or facial nerve paresis. The mean surgical duration was 39.7 ±â€Š11.5 minutes. No patients were recorded to have unsatisfactory external scar and further intervention was not required. CONCLUSION: The described percutaneous approach to mandibular angle fracture can be done effectively and safely using available and operatively fabricated disposable tools.


Subject(s)
Fracture Fixation, Internal/methods , Mandibular Fractures/surgery , Open Fracture Reduction/methods , Adolescent , Adult , Bone Plates , Bone Screws , Humans , Male , Operative Time , Young Adult
15.
J Craniofac Surg ; 27(8): e743-e745, 2016 Nov.
Article in English | MEDLINE | ID: mdl-28005805

ABSTRACT

OBJECTIVE: To detect site of the mental nerve foramen in patients of mandibular fracture and study its relation to mandibular fracture site using radiology and operative findings during open reduction and internal fixation. PATIENTS AND METHODS: This study was carried out on 46 patients who had traumatic mandibular fractures. All patients were managed by open reduction and internal fixation during which mental foramen site and fracture site were reported and analyzed and compared to preoperative radiography. RESULTS: By both radiology and operative findings, the mental foramen was found in 78.3% between the first and second premolar, and in 21.7% below the first premolar. While no other mental foramen sites were reported. There were no statistically significant differences between both detected sites as regard age and sex. By operative dissection, mental foramen and neurovascular bundle could be detected, dissected, and preserved in all patients. CONCLUSION: To the best of the authors' knowledge, this is the first operative and radiological work that highlights the site and relation of mental foramen site to mandibular fracture in Arab people. The authors' study provides useful data of mental foramen among Arab population for the surgeons, anesthetists, and dentists to carry out procedures without complications.


Subject(s)
Fracture Fixation, Internal/methods , Mandible/diagnostic imaging , Mandibular Fractures/diagnosis , Adolescent , Adult , Bicuspid/diagnostic imaging , Female , Follow-Up Studies , Humans , Male , Mandible/surgery , Mandibular Fractures/surgery , Prospective Studies , Tomography, Spiral Computed/methods , Young Adult
16.
Eur Arch Otorhinolaryngol ; 273(12): 4305-4314, 2016 Dec.
Article in English | MEDLINE | ID: mdl-27295175

ABSTRACT

Spontaneous cerebrospinal fluid leak with meningoencephaloceles in sphenoid sinus lateral recess is challenging. Transnasal visualization of this area is difficult, especially when large pneumatization is present. External approaches to this region involve aggressive surgery and are often associated with significant morbidity. The aim of this study is to assess the real effectiveness of a modification of the endoscopic endonasal approach for their management. This is a prospective case series study and was conducted at Otolaryngology department, Ain Shams University Hospitals, Cairo, Egypt. Seven patients with spontaneous cerebrospinal fluid leak with meningoencephaloceles in the sphenoid sinus lateral recess were included. Diagnosis was confirmed by: analysis for beta-2 transferrin and imaging. They were managed with endoscopic endonasal retrograde trans-sphenoid approach described in this study with multilayered reconstruction of the defect. Mean age of our patients was 40.14 ± 8.35 years; mean BMI was 36.37 ± 2.59 kg/m2. Primary empty sella was present and osteodural defect was identified in superior wall of sphenoid sinus lateral recess with punched out and regular smooth edges. Mean intra-cranial pressure was (26.42 ± 3.87 mmH2O) and size of defect was less than 10 mm, mean 7.85 ± 1.34. Mean-operative time was 169.28 ± 21.87 min. The mean hospital stay was 7.42 ± 1.39 days. No cerebrospinal fluid leak recurrences were observed during follow-up period that ranged from 37 to 48 months. Endoscopic endonasal retrograde trans-sphenoid approach provides a wide, safe, and direct route to the management of sphenoid sinus lateral recess cerebrospinal fluid leak.


Subject(s)
Encephalocele/surgery , Natural Orifice Endoscopic Surgery/methods , Paranasal Sinus Diseases/surgery , Sphenoid Sinus/surgery , Adult , Cerebrospinal Fluid Rhinorrhea/diagnosis , Disease Management , Egypt , Encephalocele/diagnostic imaging , Feasibility Studies , Female , Humans , Male , Middle Aged , Prospective Studies , Recurrence , Sphenoid Sinus/diagnostic imaging , Transverse Sinuses
17.
J Int Adv Otol ; 11(1): 92-4, 2015 Apr.
Article in English | MEDLINE | ID: mdl-26223727

ABSTRACT

Lipomas, the most common benign tumors, rarely originate from the external ear. The first case of a lipoma originating from the concha of the auricle was reported and described in the current study. It was successfully removed under local anesthesia. This directs the attention of surgeons toward lipomas as a cause of conchal mass because the early diagnosis of a lipoma when it is still small allows its easy, safe, and complete removal.


Subject(s)
Ear Auricle , Ear Neoplasms/diagnosis , Lipoma/diagnosis , Adult , Ear Neoplasms/surgery , Humans , Lipoma/surgery , Male , Otologic Surgical Procedures
18.
Oral Maxillofac Surg ; 19(4): 375-9, 2015 Dec.
Article in English | MEDLINE | ID: mdl-25934247

ABSTRACT

OBJECTIVE: The aim of this study was to assess the activity of the masseter and temporalis muscles using surface electromyography (EMG) in patients with zygomaticomaxillary complex (ZMC) fractures. PATIENTS AND METHODS: This prospective study was carried out on 25 patients who had ZMC fractures. Fifteen patients were managed by open reduction and rigid fixation (ORIF) using titanium miniplates. This study, using surface electromyography, analyzed the activity of the masseter and temporalis muscles of 25 patients with ZMC fractures; 15 of them were surgically treated under general anesthesia (GA). Evaluations were made before surgery and 6 weeks after surgery by recording the mean of muscle contraction of 20 motor unit action potential (MUAP) against resistance, and statistical analyses were performed. RESULTS: A significant EMG difference between the normal and ZMC fracture sides was found (P < 0.0001) for both masseter and temporalis muscles and was significantly improved after ORIF. However, postoperative EMV values of the repaired side was significantly less than measured postoperatively in the normal side (P < 0.0001) for both muscles. CONCLUSION: ZMC fractures significantly diminish muscular activity of the masseter and temporalis and even though significant recovery of muscle activity was revealed after 6 weeks, it is still less than normal activity, highlighting the importance of postoperative rehabilitation.


Subject(s)
Electromyography , Maxillary Fractures/physiopathology , Zygomatic Fractures/physiopathology , Adolescent , Adult , Female , Fracture Fixation , Humans , Male , Masseter Muscle/physiopathology , Maxillary Fractures/surgery , Middle Aged , Temporal Muscle/physiopathology , Young Adult , Zygomatic Fractures/surgery
19.
Eur Arch Otorhinolaryngol ; 272(5): 1189-93, 2015 May.
Article in English | MEDLINE | ID: mdl-25649284

ABSTRACT

Leukoplakia is a descriptive clinical term designating a white patch or plaque of the mucosa and must be complemented by histology, which can range from simple totally benign keratosis with or without atypia up to invasive carcinoma. The aim of this study is to evaluate the accuracy of videostroboscopy in preoperative differentiation of early invasive glottic carcinoma from intraepithelial atypia and dysplasia. 46 patients with a total of 60 leukoplakia lesions on the vocal folds were included in the study. Videostroboscopy was used to divide them into two groups based on preservation of the mucosal wave and this was correlated with the final pathology after treatment. The sensitivity and specificity of videostroboscopy in predicting invasive nature of the lesions based on absence or reduction of the mucosal wave were 96.8 and 92.8 %, respectively, with an overall accuracy of 95 %. We suggest that routine application of videostroboscopy can be an important, simple, non-invasive tool, to achieve, in a single procedure, proper and accurate evaluation of glottic leukoplakia.


Subject(s)
Carcinoma , Glottis , Laryngeal Neoplasms , Stroboscopy/methods , Adult , Carcinoma/pathology , Carcinoma/surgery , Diagnosis, Differential , Female , Glottis/pathology , Glottis/surgery , Humans , Hyperplasia/diagnosis , Laryngeal Neoplasms/pathology , Laryngeal Neoplasms/surgery , Leukoplakia/diagnosis , Male , Middle Aged , Neoplasm Invasiveness , Patient Selection , Precancerous Conditions , Predictive Value of Tests , Preoperative Care , Sensitivity and Specificity
20.
Int J Pediatr Otorhinolaryngol ; 79(1): 23-5, 2015 Jan.
Article in English | MEDLINE | ID: mdl-25465445

ABSTRACT

OBJECTIVES: The aim of this study is to investigate the efficacy of topical application of mitomycin C after dilation in pediatric patients having post corrosive esophageal stricture. METHODS: Thirty patients with post corrosive esophageal strictures were divided into two groups: 12 patients had repeated esophageal dilation without mitomycin C application, 18 patients had repeated esophageal dilation and topical application of mitomycin C. RESULTS: There was a highly significant difference in the improvement of dysphagia grade at the end of follow up in the mitomycin C group (p=0.005). The number of repetition of dilatation ranged from 2 to 6 (median=3) in the 1st group, and 2 to 4 (median=2.5) in the mitomycin C group. There were no adverse effects from the topical application of the mitomycin C. CONCLUSIONS: Topical application of mitomycin C after oesophageal dilation can be beneficial in improving dysphagia in patients with post corrosive oesophageal stricture.


Subject(s)
Antibiotics, Antineoplastic/therapeutic use , Burns, Chemical/complications , Dilatation , Esophageal Stenosis/therapy , Mitomycin/therapeutic use , Administration, Topical , Caustics , Child , Child, Preschool , Deglutition Disorders/etiology , Deglutition Disorders/therapy , Esophageal Stenosis/etiology , Esophagoscopy , Female , Humans , Male , Prospective Studies , Severity of Illness Index
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