ABSTRACT
The aim of the study was to estimate somatic development of children who recovered from secondary malabsorbtion syndrome. We examined 24 children 2.5-13 years old. Their weight when diagnosed was between 10-3 percentiles. Patients were treated with gluten free diet 8-36 month. After recovery (normal mucose in biopsy) 20 children (83.3%) had normal somatic development and 4 (16.7%) abnormal development. This abnormal development was caused by infantile cerebral palsy and Silver-Russel syndrome. Therapy by elimination diets gave villi regeneration and normal development in most of our patients.
Subject(s)
Child Development/physiology , Glutens/metabolism , Malabsorption Syndromes/diet therapy , Malabsorption Syndromes/metabolism , Recovery of Function , Adolescent , Cerebral Palsy/complications , Child , Child, Preschool , Female , Humans , Malabsorption Syndromes/etiology , Male , SyndromeABSTRACT
AIM: The aim of the study was the estimation of the incidence of HCV infection and the analysis of risk factors for the infection in hospitalized children. MATERIAL AND METHODS: Retrospective analysis of the data of 1263 patients treated in hospital wards of Chair and Department of Gastroenterology and Paediatric Diseases from July 1995 to March 1998; all the patients had hepatitis C virus antibodies determined. Hepatitis C virus antibodies were assessed with the use of enzyme immunoassay. All the positive results were confirmed by means of Lia Tek HCV or PCR HCV RNA method. History data regarding frequency of previous hospitalizations, operations, blood transfusions and invasive diagnostic procedures patients had undergone were included in analysis. RESULTS: HCV infection was diagnosed in 47 children which accounted for 3.7% of the group enrolled in the study. The majority, that is 96.2% of seropositive children had the history of hospitalization, while 73.2% of them underwent intervention procedures disrupting tissue continuity during previous hospitalizations. Physical examination analysis indicates that all the patients with antibodies against HCV could have acquired the infection through parenteral transmission. The data indicating another route of transmission were not obtained (e.g. familial transmission). CONCLUSIONS: 1. Serological tests for HCV infection should be performed on routine basis in frequently hospitalized children. 2. HCV infection resulting from iatrogenic transmission can be suspected in the majority of seropositive children.
Subject(s)
Cross Infection/epidemiology , Hepatitis C/epidemiology , Hospitalization , Adolescent , Child , Child, Preschool , Cross Infection/etiology , Cross Infection/immunology , Cross Infection/transmission , Female , Hepatitis C/etiology , Hepatitis C/immunology , Hepatitis C/transmission , Hepatitis C Antibodies/blood , Humans , Iatrogenic Disease/epidemiology , Infant , Male , Poland/epidemiology , Retrospective Studies , Risk FactorsABSTRACT
During a period of 10 months, 87 children with Pneumocystis carinii pneumonia accompanied transient cellular immunity disorders and with normal humoral immunity were observed. It is suggested that change the invasiveness of the parasite has changed. The necessity of taking into consideration a pneumocystis etiology in diagnosis of respiratory tract diseases among children is pointed out.
Subject(s)
Pneumonia, Pneumocystis/diagnosis , Respiratory Tract Diseases/etiology , Adolescent , Antibody Formation/immunology , Child , Child, Preschool , Female , Humans , Immunity, Cellular/immunology , Infant , Infant, Newborn , Male , Pneumocystis/pathogenicity , Pneumonia, Pneumocystis/complications , Pneumonia, Pneumocystis/immunologyABSTRACT
In recent years a shift in incidence of coeliac disease from the classical to late-onset form has been observed. The main, and often only, symptom of late onset coeliac disease is short stature. The presence of antiendomysial antibodies was found in 14 of 115 children with statural height below the third percentile from randomly chosen kindergartens and schools in Bydgoszcz. Severe atrophy of the intestinal villi in a biopsy specimen confirmed the suspicion of coeliac disease in these children. IgA-EmA are markers of coeliac disease in children with short stature and should be used as a screening test in looking for the causes of short stature.
Subject(s)
Antibodies/analysis , Celiac Disease/diagnosis , Celiac Disease/prevention & control , Growth Disorders/prevention & control , Immunoglobulin A/analysis , Myofibrils/immunology , Adolescent , Biomarkers/analysis , Celiac Disease/complications , Child , Child, Preschool , Growth Disorders/etiology , Humans , Mass ScreeningABSTRACT
Burns are the most frequent severe trauma in childhood. Curling's ulcer is a complication of burn shock which occurs in the gastrointestinal tract in burned children. Prognosis in Curling's ulcer is always serious. A rare case of acute duodenal ulcer in a nine-month-old infant after deep burns of both lower extremities is described. It seems that it is necessary to take into consideration the possibility of Curling's ulcer in every case of deep and extensive burns in children.
Subject(s)
Burns/complications , Duodenal Ulcer/etiology , Humans , Infant , MaleABSTRACT
The study encompassed 100 children who recovered from secondary malabsorption syndrome. The following were evaluated: physical development (body weight, height, skin-fold thickness on the arm, shoulder-blade and abdomen) and IQ in the Wechsler scale. Children who had suffered from secondary malabsorption syndrome in infancy showed lower parameters of physical development compared with healthy children. These differences pertained mainly to body weight and height and to the intelligence quotient.
Subject(s)
Child Development , Malabsorption Syndromes/diagnosis , Malabsorption Syndromes/psychology , Abdomen , Child , Child, Preschool , Humans , Intelligence , Intelligence Tests , Retrospective Studies , Shoulder , Skinfold ThicknessABSTRACT
A congenital disorder syndrome defined by literature as the Alperts'-Crouzon has been described for a six-year-old boy. Introduction of this case seems to be justified noting the rarity of its occurrence.
Subject(s)
Acrocephalosyndactylia/diagnosis , Craniofacial Dysostosis/diagnosis , Child , Humans , Male , SyndromeABSTRACT
The fates of 97 children hospitalized for malnutrition syndrome in the years 1983-1985 were assessed depending on the aetiology and treatment. In all cases the first biopsy of the small intestine demonstrated the so called flat mucosa. In recent years a continuous rise has been observed in the number of children with malabsorption syndromes, especially secondary syndromes caused, most frequently, by infectious factor and antibiotic treatment given for infections. The number of such cases was in 1985 four times greater than in 1983. A proper diagnostic-therapeutic management led to complete regeneration of intestinal villi in all cases. The further development of these children was normal.