ABSTRACT
An outbreak of immature paramphistomosis in Nellore Jodipi sheep was recorded in Nellore district of Andhra Pradesh in 158 sheep during the months of April-June-2012. The condition is diagnosed as immature paramphistomosis on the basis of symptoms, dung sample examination and necropsy findings. The infected sheep exhibited symptoms like persistent foetid, blackish diarrhoea, sub maxillary edema, dehydration and death. Necropsy findings include hemorrhagic thickening and necrosis of proximal duodenal mucosa, ascites, gelatinization of subcutaneous and renal fat. Duodenal scrapings revealed large number of immature paramphistomes under low power microscopy. Recovery of ailing sheep was observed after oral treatment of niclosamide @ of 100 mg/kg bwt along with supportive therapy.