ABSTRACT
It was determined that a long-lasting consumption of a finely-growing feed vivarium even in the early postnatal period (60 days) causes certain changes in liver hepatocytes in rats. There takes place nucleous area and cell cytoplasm diminishing, accompanied by a decrease of albumines' synthesis level. In the later postnatal period (120 days) the hepatocytes' nucleus and cytoplasm area drastically increases, which is accompanied by the increase of albumine content in blood up to reference values. During the following period of the natal development (120-180 days) the levels as on the 128th day of the animals' development. In such a case the nucleous area slightly diminishes.
Subject(s)
Animal Feed , Hepatocytes/ultrastructure , Liver , Aging/metabolism , Aging/pathology , Albumins/biosynthesis , Animal Feed/adverse effects , Animal Feed/analysis , Animal Feed/standards , Animals , Animals, Laboratory , Cell Nucleus/metabolism , Cell Nucleus/ultrastructure , Cytoplasm/metabolism , Cytoplasm/ultrastructure , Hepatocytes/metabolism , Liver/growth & development , Liver/metabolism , Liver/ultrastructure , Male , Rats , Time FactorsSubject(s)
Foods, Specialized , Gastric Fundus/pathology , Muscle, Smooth/pathology , Adaptation, Physiological , Animal Feed , Animal Nutritional Physiological Phenomena , Animals , Gastric Fundus/growth & development , Hypertrophy/pathology , Male , Morphogenesis , Muscle, Smooth/growth & development , RatsABSTRACT
The aim of research is influence dispersant food on morphological peculiarities of white rat's mucosa colon. It is determined morphological peculiarities animal's colon mucosa under the influence dispersant food in particularly reduction mucous thickness and mitotic index crypt, decreasing of goblet cells in the epithelial layer.
Subject(s)
Colon/pathology , Foods, Specialized , Intestinal Mucosa/pathology , Animal Feed , Animals , Colon/growth & development , Intestinal Mucosa/growth & development , Male , Rats , Time FactorsABSTRACT
Mitotic index of type B spermatogonia in intact animals is characterized by a circadian rhythm. Mitotic index increased and its circadian rhythm disappeared after pinealectomy. Treatment with Epithalamin for 14 days restored the circadian rhythm. The circadian biorhythm of spermatogonia proliferation suggests the presence of circadian rhythm of spermatogenesis in general and its regulation by the pineal gland.
Subject(s)
Circadian Rhythm/drug effects , Mitosis/physiology , Peptides/pharmacology , Pineal Gland/chemistry , Spermatogonia/physiology , Animals , Antineoplastic Agents/pharmacology , Male , Photoperiod , Pineal Gland/surgery , Rats , Spermatogonia/cytology , Spermatogonia/drug effectsABSTRACT
The mitotic index of spermatogonia and 24-h dynamics of stages IV, VI, and XIV of spermatogenic cycle are characterized by circadian rhythm. No circadian rhythm was detected for 11 of 14 stages. Pinealectomy led to an increase of the mitotic index of spermatogonia but did not modulate the incidence of spermatogenic cycle stages, and led to disappearance of the circadian rhythm of both the mitotic index and spermatogenic cycle stages.
