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Tsitol Genet ; 47(1): 50-5, 2013.
Article in Ukrainian | MEDLINE | ID: mdl-23427612

ABSTRACT

Peculiarities of repair of DNA injuries induced by radiation and hyperthermia and their realization on chromosomal level in bone marrow cells ofexperimental animals with different radiation sensitivity were studied. It is shown that radiomodification efficiency of mild hyperthermia is higher for radioresistant animals. More intensive elimination of chromosomal injuries the level of which in remote terms of examination corresponds to the control value, is observed. In the group of animals with higher radiation sensitivity prolonged thermal potentiation of radiation effects on chromosomal level is determined.


Subject(s)
Bone Marrow/radiation effects , Chromosome Aberrations , Chromosomes, Mammalian/radiation effects , Metaphase/radiation effects , Radiation Tolerance , Animals , Bone Marrow/pathology , Comet Assay , DNA Damage , DNA Repair , Dose-Response Relationship, Radiation , Fever , Mice , Mice, Inbred C3H , Mice, Inbred CBA , Whole-Body Irradiation , X-Rays
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