1.
J Appl Bacteriol
; 51(1): 143-7, 1981 Aug.
Article
in English
| MEDLINE
| ID: mdl-7275869
2.
Int Arch Allergy Appl Immunol
; 63(2): 195-200, 1980.
Article
in English
| MEDLINE
| ID: mdl-6158483
ABSTRACT
In vitro studies on mitogenic stimulation of lymphocytes from a panel of normal volunteers revealed no transformation in response to the presence of dextran 40, 70, 110 or 150 at concentrations ranging from 0.8 to 8,000 microgram/ml. High molecular weight native dextran B512 was mitogenic in 1 individual only. In addition, neither Leuconostoc-derived nor fermentation medium-derived moieties, sometimes present in clinical dextrans, were implicated as lymphocyte mitogens. It is concluded on the basis of these findings that clinical dextrans of average molecular weight 40,000--150,000 are not B- or T-cell mitogens.