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Brain Res Dev Brain Res ; 157(2): 217-9, 2005 Jun 30.
Article in English | MEDLINE | ID: mdl-15936828

ABSTRACT

Adult rats (prenatally methamphetamine-exposed, saline-exposed and controls) were tested for learning in the Morris water maze. Rats were tested in 4 consecutive days using two different types of learning tests: "Place navigation test" (stable platform position) and "New-learning test" (platform position changed daily). Males exposed prenatally to methamphetamine were slower in the Place navigation learning test than were both the control and saline-exposed males. There were no differences in the New-learning test between groups.


Subject(s)
Brain/drug effects , Brain/growth & development , Learning Disabilities/chemically induced , Memory Disorders/chemically induced , Methamphetamine/adverse effects , Prenatal Exposure Delayed Effects , Amphetamine-Related Disorders/physiopathology , Animals , Brain/physiopathology , Central Nervous System Stimulants/adverse effects , Disease Models, Animal , Female , Learning Disabilities/physiopathology , Male , Maze Learning/drug effects , Maze Learning/physiology , Memory/drug effects , Memory/physiology , Memory Disorders/physiopathology , Orientation/drug effects , Orientation/physiology , Pregnancy , Rats , Rats, Wistar , Sex Characteristics , Sex Factors
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