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1.
Morfologiia ; 149(2): 73-6, 2016.
Article in Russian | MEDLINE | ID: mdl-30136808

ABSTRACT

Iba-1 protein which is a recognized marker of the microglial cells, was previously detected by the authors in the nucleus of microgliocytes. The present study was aimed to define more exactly these data using the methods of immunohistochemistry and confocal laser microscopy. The study was performed on the fragments of the human brain (n=18, age 25­78 years). The areas examined included cortex, striatum, substantia nigra, and nucleus rubrum. The Iba-1 protein was shown to accumulate in one or several parts of microgliocyte nucleus not identical to the nucleolus or the heterochromatin granules. The reasons for this fact are unclear. It may be speculated that Iba-1 protein besides its major function (involvement in phagocytosis) can perform the role of a transcriptional factor.


Subject(s)
Brain/metabolism , Cell Nucleus/metabolism , DNA-Binding Proteins/metabolism , Microglia/metabolism , Phagocytosis , Transcription Factors/metabolism , Adult , Aged , Brain/cytology , Calcium-Binding Proteins , Female , Humans , Male , Microfilament Proteins , Microglia/cytology , Middle Aged
2.
Morfologiia ; 145(1): 60-2, 2014.
Article in Russian | MEDLINE | ID: mdl-25051803

ABSTRACT

This paper describes the study of the neuroepithelial bodies (NEB) in the lungs of adult healthy Wistar rats (n = 12). Using the immunocytochemical reaction demonstrating synaptophysin, NEB and immunopositive nerve terminals approaching them, were visualized. It was found that NEB were the structures constantly presented in the rat lung. In contrast to the diffuse neuroendocrine elements, NEB are characterized by grouped distribution of cells. It was found that some part of NEB had no efferent innervation.


Subject(s)
Lung/cytology , Neuroepithelial Bodies/cytology , Animals , Lung/innervation , Lung/metabolism , Neuroepithelial Bodies/metabolism , Peripheral Nerves/cytology , Rats , Rats, Wistar , Synaptophysin/genetics , Synaptophysin/metabolism
3.
Gig Sanit ; (9): 55-7, 1991 Sep.
Article in Russian | MEDLINE | ID: mdl-1790870

ABSTRACT

Hygienic assessment of teaching conditions and ability to work of pupils in primary school under five day a week education were studied. Significant "physiological cost" of teaching and difficulties in adaptation of pupils were noted.


Subject(s)
Hygiene , Teaching , Child , Humans , Models, Statistical , Time Factors
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