ABSTRACT
A radio-dense metaphyseal band (MB) of different width is present at the distal end of the radius in growing children. Authors studied 30 prepubertal children before and after one and two years of treatment by recombinant human growth hormone (rhGH). They examined the relationship between the MB, bone age (BA), height velocity (HV) and insulin like growth factor-I (IGF-I). However all the four parameters showed significant change in the study period, correlation was found only after the second year of treatment between the change MB and IGF-I levels. Authors suggest that the regulation of bone growth in these children can be compared only after two years to the normally growing children.
Subject(s)
Growth Hormone/analogs & derivatives , Insulin-Like Growth Factor I/metabolism , Radius/growth & development , Recombinant Proteins/therapeutic use , Child , Child, Preschool , Female , Growth Disorders/drug therapy , Growth Disorders/metabolism , Growth Hormone/deficiency , Growth Hormone/pharmacology , Growth Hormone/therapeutic use , Human Growth Hormone , Humans , Male , Radius/anatomy & histology , Radius/drug effects , Recombinant Proteins/pharmacologyABSTRACT
The aim of this study was to present the normal thyroid volumes of Budapest school-children (from central- and confine-districts). Real-time ultrasound instrument was used in study of 1328 children. Authors applied the method of Brunn et al. to calculate the size of every single thyroid lobes. Percentile curves of thyroid volumes were prepared on the basis of the results in both sexes and age between 6 and 14 years. Authors refer to the correlation between size of thyroid and (changing) body measurements according to the age and sexes. The frequency of symptomless abnormalities is mentioned in this population supporting the usefulness of thyroid sonography as a screening method.
