Reduction in edge effects for small panels characterized by a parametric array source.

This study sought to explore effects of panel size on underwater acoustic transmission and reflection measurements made with a truncated parametric array source. The transmission loss (TL) and reflection loss spectra of aluminum panels of several different sizes were determined experimentally, and compared to predictions from plane wave theory in the 5-100 kHz frequency range. For the smallest panel size, there were significant discrepancies between experimental data and plane wave theory, which were attributed to contributions from edge-diffracted waves and interferences from the mounting fixture for the panel. For reflection measurements, the latter interference could be corrected for in part by measurement of the reflected signal from the sample holder (with no panel present), and subtracting this signal from reference and test panel waveforms. In order to reduce the contributions from edge diffracted waves in TL measurements, an alternative panel mounting system was investigated, which involved surrounding the panel in a reflective baffle. There was a significant improvement in agreement of experimental TL spectra with plane wave theory for the smallest aluminum panel when the baffle mounting arrangement was used.

Rapid radiosynthesis of two [18F]-labeled nicotinamide derivatives for malignant melanoma imaging.

The rapid synthesis of two radiofluoronicotinamide derivatives, namely, [18F]MEL050 and [18F]MEL-2F has been simply performed starting from commercial materials. [18F]MEL-2F is a new, potential analogue PET-probe for melanoma imaging. [18F]MEL050 is already an excellent PET imaging probe for early specific diagnosis. The synthesis involves coupling step to obtain the precursor followed by radiofluorination. During the synthesis of the precursors different coupling reagents, such as HBTU, TFFH, HOBT, COMU and PyCIU have been applied. PyClU was found the best to reduce the coupling period to < 1h. The labeled compounds were isolated and purified by HPLC. In the in-vitro study three kinds of cells, namely, Melur (melanin free), KB-3 carcinoma cell line (non-melanoma) and B16-F10 melanoma cell line were used to evaluate the uptake of the radiotracers.

Three-dimensional elasticity model for a decoupling coating on a rectangular plate immersed in a heavy fluid.

This paper presents an analysis of the vibroacoustic response of a finite, simply supported rectangular plate covered by a layer of decoupling material and immersed in a heavy fluid. An exact formulation using the three-dimensional theory of elasticity for the decoupling material is derived for this problem, thereby extending previous studies that were limited to infinite plates. The paper details the constitutive equations of the problem and the analytical method of solution. Numerical results show that shear waves in the decoupling material generally have little influence on the sound radiation in the heavy fluid. Comparisons with a locally reacting model of the decoupling material and with the simple model of House [Proc. I.O.A. 13(3), 166-173 (1991)] are also presented.