ABSTRACT
Lymphoepithelial carcinoma of the salivary glands is a rare type of cancer that is poorly differentiated and resembles undifferentiated nasopharyngeal carcinomas. However, it requires a completely different treatment regimen. This type of cancer is more common in certain populations, particularly Asians and Arctic region native populations, and is strongly associated with the Epstein-Barr virus, especially in endemic areas. The most common symptoms of this type of cancer include a growing mass in the parotid region and cervical lymphadenopathy. In this study, the authors present the case of an unusual instance of Epstein-Barr virus positive lymphoepithelial carcinoma in the parotid gland. The authors reviewed the literature and report a case history to present the diagnostic steps and the management of lymphoepithelial carcinoma in the parotid gland. Orv Hetil. 2023; 164(38): 1506-1510.