ABSTRACT
INTRODUCTION: Practitioners have anecdotally hinted at a possible association between gastroesophageal reflux disease (GERD) and vesicoureteral reflux (VUR). We sought to identify an association in diagnosis between GERD and VUR using a population-based dataset in a well-defined geographic area covered by a single-payer healthcare system. METHODS: A retrospective review of individuals aged 0-16 years registered in the Nova Scotia Medical Service Insurance database from January 1997 to December 2012 was completed. Presence of GERD and VUR were ascertained based on billing codes. The baseline prevalence of GERD and VUR was calculated for this population for the same time period. Proportions of VUR patients with and without GERD were compared. The risk of being diagnosed with VUR in patients with GERD controlling for sex was calculated. RESULTS: Of 404 300 patients identified, 6.6% had a diagnosis of GERD (n=27 092), 0.33% had a diagnosis of VUR (n=1348), and 0.08% were diagnosed with both (n=327). Among patients with VUR, the prevalence of GERD was 24.3% compared to 6.6% in patients without VUR (p<0.0001). Among patients with GERD, the prevalence of VUR was 1.2% compared to 0.27% in patients without (p<0.0001). The risk of being diagnosed with VUR was higher in the presence of GERD (odds ratio [OR] 4.49; 95% confidence interval [CI] 3.96-5.09; p<0.0001), irrespective of sex. CONCLUSIONS: The odds of being diagnosed with VUR is more than 4.5 times higher in an individual with GERD. The clinical significance of this association remains to be explored.
ABSTRACT
OBJECTIVE: To evaluate the effectiveness of audiovisual distraction compared with a blank TV screen in the reduction of pain associated with intramuscular immunization. DESIGN: Subjects were randomly assigned to watch television (TV) (N = 29) or a blank TV screen (control) (N = 33) during immunization, and were videotaped. Immediately after the injection, the children rated their pain. Videotapes were coded for pain behaviors and for distraction. t tests determined between-group mean differences and chi-square tests compared proportions for clinically significant self-reported pain. SETTING: Two urban pediatric practices in Halifax, Nova Scotia, Canada. SUBJECTS: Five-year-old children (N = 62), undergoing diphtheria, polio, tetanus, and pertussis immunization, and their parents. INTERVENTIONS: An age-appropriate musical cartoon or a blank TV screen. OUTCOME MEASURES: Pain measurements were the children's self-reports on Faces Pain Scale, facial actions on Child Facial Coding System, and Children's Hospital of Eastern Ontario Pain Scale. Distraction was measured by mean time spent watching the TV screen. Parents rated their own and their child's anxiety on a visual analogue scale. RESULTS: There were no significant group differences for any pain or distraction measures. The relative risk estimate for clinically significant pain among the distraction group was 0.64 (range: 0.23-1.80). Higher levels of distraction (i.e., greater time looking at the TV screen) related to lower levels of pain on all three pain measures. Only correlations with objective pain measures were statistically significant. CONCLUSIONS: Watching cartoons did not distract children during needle injection nor reduce their pain. Looking at the TV screen was related to lower behavioral pain scores in the total sample.
