[Viscosity of blood and plasma in patients with single- and multi-vascular coronary heart disease]. / Lepkosc krwi i osocza u chorych z jedno- i wielonaczyniowa choroba wiencowa.

The aim of this study was to establish a connection between rheological disturbances and extensiveness of atherosclerotic changes in coronary angiogram. Patients were classified into two groups: group I--with multivascular atherosclerotic lesions (45 subjects at age of 58 +/- 11 years), group II--with univascular atherosclerotic lesions (18 subjects at age of 55 +/- 9 years). Blood samples were drawn from the cubital vein prior to the angiogram. Blood viscosity measurements were performed using low-shear Contraves viscometer-100 at 0.116; 1.0; 4.59 s-1 shear rates and Brokfield Cone/Plate Viscometer at 150 s-1. The plasma viscosity was measured by means of Ubbelohde's capilary viscometer. Besides the viscometric examinations the total cholesterol. LDL-cholesterol, HDL-cholesterol, triglycerides, glucose and fibrinogen as well as blood morphology and ESR were determined. All rheological measurements were carried out at the temperature of 37 degrees C immediately after blood drawing. The results of studies indicate that in patients with multivascular coronary disease whole blood viscosity at all examined shear rates was significantly greater then in univascular patients. It was found that the LDL-lipoproteins concentration was significantly elevated in the I group. Other examined parameters did not differ significantly. The examinations indicate that there exists the connection between hemorheological disturbances and the extensiveness of coronary heart disease.

[Chosen function of peripheral blood neutrophils in workers operating X-ray equipment]. / Wybrane funkcje neutrofilów krwi obwodowej u pracowników obslugujacych aparature rentgenowska.

Examinations were carried out in 44 persons (29 women and 15 men) who operated X-ray equipment in radiology departments. Neutrophil adherence and spontaneous migration of leukocytes were estimated in this group. Investigations' results were compared with the results in the control group. In the group of employees who operated X-ray units, the examinations were additionally performed taking sex into consideration. In the persons employed in radiology departments statistically significant reduction of neutrophil adherence was shown, which especially in the subgroup of men was observed. Statistically significant reduction of spontaneous migration area of leukocytes was revealed and it concerned both the subgroup of men and subgroup of women. On the basis of the obtained results the following conclusions were drawn: leukocyte spontaneous migration estimated in three-hour test decreases in employees who operated X-ray units; it may be used as the estimation test of influence of the X-ray on employees operating X-ray equipment when the routine tests are in the normal range.

[Blood and serum viscosity in cardiologic X syndrome]. / Lepkosc krwi i osocza w kardiologicznym zespole X.

UNLABELLED: The aim of this study was to explore if are there blood rheological disturbances in cardiac syndrome X. Two groups were examined: 23 patients (aged 41 divided by 72 years) suffering from cardiac syndrome X (typical anginal pain positive stress test and no lesion in coronary angiograms) and 20 healthy (aged 32 divided by 57 years). Blood samples were drawn from the cubital vein prior to the angiogram. Blood viscosity measurements were performed using the Brookfield Cone/Plate Viscosimeter at 150 s-1 shear rate, and by means of low-shear Contraves viscometer at 1 s-1 (a)nd 4.59 s-1 shear rates. The plasma viscosity was measured by means of Ubbelohde's capillary viscometer. Besides the viscometric examinations the total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides and glucose plasma concentration as well as blood morphology and ESR were determined. All rheological measurements were carried out at the temperature of 37 degrees C immediately after blood drawing. It was stated that blood and plasma viscosity were significantly elevated in syndrome X compared with the control group (p < 0.001). CONCLUSION: The examinations indicate that in patients suffering from Cardiological Syndrome X the whole blood and plasma viscosity are increased.

[Restenosis after percutaneous coronary angioplasty--cause, prevention strategies]. / Restenoza po przezskórnej angioplastyce wiencowej--mechanizm powstawania, próby zapobiegania.

PTCA is a new method of invasive cardiology. Restenosis is an important limitation of efficacy of this method. It occurs in 20-45% of patients. Pathomechanism of the restenosis is not clear. It is assumed, that restenosis is an answer of the endothelium to the procedure. This response consists of the inflammation, platelet primary adhesion and aggregation, proliferation of smooth muscle cells and intercellular matrix production. These changes together with old atheroma and thrombus create a new stenosis. There were many attempts to prevent restenosis based on the pathophysiology, but so far no successful method has been found.