ABSTRACT
The authors report on the experiences with cervical myelography performed in 94 cases in the past years at their Institute. On the basis of the results a simple and reliable procedure easy to perform with the lumbar administration of Omnipaque contrast material in lying position is described and recommended. Examinations performed by cervical puncture are justified only according to the authors' opinion if their method fails to be successful.
Subject(s)
Myelography/methods , Cervical Vertebrae , Contrast Media/administration & dosage , Humans , Injections , Lumbar VertebraeSubject(s)
Brain Neoplasms/diagnosis , Magnetic Resonance Imaging , Tomography, X-Ray Computed , Adult , Aged , Brain Neoplasms/classification , Female , Humans , Male , Middle AgedABSTRACT
The effectiveness of indomethacin treatment (1 mg/kg) as an antipyretic was tested in patients after cranial trauma or brain surgery involving the centromedial forebrain. Indomethacin was effective in reducing temperature in 10 of 11 cases which showed a dipyrone-resistant hyperthermia developing in the first 24 hours after brain damage, while no significant antipyretic effect was seen in hyperthermic cases developing more than 72 hours after cranial trauma or brain surgery. Biochemical tests estimating the effect of indomethacin, and pyrazolone derivatives on the arachidonic acid metabolism showed significant effects of indomethacin only in influencing cyclooxygenase activity and no effect of any drugs on lipoxygenase actions. In view of these observations, the use of indomethacin is recommended as a treatment for neurogenic hyperthermia.