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Z Gastroenterol ; 27(10): 624-8, 1989 Oct.
Article in German | MEDLINE | ID: mdl-2555975

ABSTRACT

In a clinical study (1.1.1986-28.2.1988) the oro-cecal transit time of lactulose was studied in 45 patients with liver cirrhosis of different etiologies by hydrogen breath test. The results were compared to the transit time of 16 healthy volunteers. The oro-cecal transit time of patients with alcoholic cirrhosis (means = 154 +/- 29 min.) was significantly increased (P less than or equal to 0.001) while non alcoholic cirrhosis (means = 99 +/- 34 min.) did not differ from the control group (means = 98 +/- 16 min.) As an explanation of the increased oro-cecal transit time an alcoholic autonomic neuropathy (- greater than n. vagus) is discussed.


Subject(s)
Alcoholism/physiopathology , Breath Tests/methods , Gastrointestinal Transit , Hydrogen/analysis , Liver Cirrhosis, Alcoholic/physiopathology , Digestive System/innervation , Electromyography , Female , Humans , Lactulose , Male , Middle Aged , Peripheral Nerves/physiopathology , Polyneuropathies/physiopathology , Synaptic Transmission , Vagus Nerve/physiopathology
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