ABSTRACT
Lymphoproliferative disorders with primary presentation in a joint are extremely rare. Posttransplantation lymphoproliferative disorders are commonly extranodal at presentation but rarely involve joint structures. The authors describe a fatal case of posttransplantation lymphoproliferative disorder presenting in the knee of a 39-year-old woman who had undergone renal transplantation many years before.
Subject(s)
Kidney Transplantation , Knee Joint , Lymphoma, Large B-Cell, Diffuse/etiology , Postoperative Complications , Amyloidosis/etiology , Antibodies, Monoclonal , Child , Fatal Outcome , Female , Humans , Joint Diseases/etiology , Joint Diseases/pathology , Kidney Failure, Chronic/surgery , Lymphoma, Large B-Cell, Diffuse/pathology , Synovial Membrane/pathology , Time FactorsABSTRACT
A series of cephalosporins derived from cephalothin containing an ester-linked quinolonyl substituent at the C-10 position (C-10 quinolonyl-cephem esters) has been prepared and evaluated for in vitro antibacterial activity. The C-10 quinolonyl-cephem esters exhibited a broadened spectrum of activity when compared with cephalothin and the corresponding quinolones, including activity against beta-lactamase-producing bacteria.
Subject(s)
Bacteria/drug effects , Cephalothin/analogs & derivatives , Quinolines/chemical synthesis , Cephalothin/chemical synthesis , Cephalothin/pharmacology , Enterobacter/drug effects , Escherichia coli/drug effects , Esters , Molecular Structure , Pseudomonas aeruginosa/drug effects , Quinolines/pharmacology , Staphylococcus aureus/drug effects , Streptococcus pneumoniae/drug effectsSubject(s)
Arthroscopy , Knee Injuries/diagnosis , Humans , Knee Injuries/surgery , Knee Joint/surgery , Reoperation , Retrospective StudiesABSTRACT
Reflex sympathetic dystrophy (RSD) is a seldom-considered diagnosis in knee pain of undetermined etiology. However, in a retrospective study of 67 patients with unexplained knee pain, 14 patients met criteria to establish the diagnosis of reflex sympathetic dystrophy. These patients' clinical profiles, physical findings, and laboratory tests and treatments support the diagnosis of reflex sympathetic dystrophy of the knee and provide guidelines for treatment of the condition.
Subject(s)
Knee Joint , Reflex Sympathetic Dystrophy/diagnosis , Adolescent , Adult , Female , Humans , Male , Middle Aged , Reflex Sympathetic Dystrophy/therapySubject(s)
Shoulder Dislocation/diagnostic imaging , Shoulder Injuries , Tendon Injuries , Adult , Humans , Male , Radiography , Rupture , Shoulder Joint/diagnostic imagingABSTRACT
The incidence of thoracic kyphosis in 91 older children and adolescents suffering from cystic fibrosis was 15.1%. Only 5.5% of 91 hospitalized "normal" adolescents had the deformity. Among the group of patients with cystic fibrosis we found a positive correlation between incidence of kyphosis and severe pulmonary disease. Because the kyphosis does not seem to represent a problem in itself, and owing to the various and multiple problems of these young people, braces are indicated only in exceptional cases with rapidly progressing deformity. A program of proper stretching, thoracic extension, and breathing exercises should be recommended for such patients.
Subject(s)
Cystic Fibrosis/complications , Kyphosis/complications , Cystic Fibrosis/diagnostic imaging , Female , Forced Expiratory Volume , Humans , Kyphosis/diagnostic imaging , Lung/diagnostic imaging , Lung/physiopathology , Male , Radiography , Vital CapacityABSTRACT
Direct and indirect trauma can cause injury to various portions of the pectoralis major muscle in varying degrees. Sprains and partial tears of the pectoralis major muscle are not uncommon. Surgical repair in acute injuries can often produce excellent results in selected patients. Complete injuries of the muscle tendon itself (Type IIID) are best treated with surgical repair in otherwise healthy patients. Delayed diagnosis and delayed repair may prevent excellent results. A functional classification as presented here can aid in the diagnosis and treatment of these injuries.
Subject(s)
Pectoralis Muscles/injuries , Adolescent , Adult , Contusions , Humans , Male , Middle Aged , Rupture , Sprains and Strains , Thoracic Injuries/therapyABSTRACT
In a consecutive retrospective study of 1,500 total hip replacements, analysis of cultures taken at the time of operation revealed that positive cultures obtained in primary arthroplasties are not significant. In our series, no statistical difference could be demonstrated between primary and revision arthroplasty cultures as related to joint infection, but on the basis of other clinical studies and the higher incidence of positive cultures in revision arthroplasty cultures as related to joint infection, but on the basis of other clinical studies and the higher incidence of positive cultures in revision arthroplasties, it is believed that these cultures should be treated vigorously. Further studies are being carried out to help clarify the role of prophylactic antibiotics in hip replacement operations in the prevention of postoperative hip joint infection. Antibiotic therapy for the treatment of potentially contaminated hips is also being reviewed. Such studies must be performed over a long term period.
Subject(s)
Bacterial Infections/prevention & control , Hip Joint/surgery , Joint Prosthesis , Postoperative Complications/prevention & control , Arthroplasty/adverse effects , Bacterial Infections/etiology , Hip Joint/microbiology , Humans , Joint Prosthesis/adverse effects , New York , Retrospective StudiesSubject(s)
Elbow Injuries , Fractures, Bone , Joint Dislocations , Adolescent , Humans , Humerus , Joint Diseases , Male , Radius , UlnaABSTRACT
This is a case report of a 25-year-old woman who developed spondylolisthesis following surgical spine fusion for treatment of congenital scoliosis. Increased biomechanical stresses and the possibility of an undetected pars interarticularis defect existing prior to fusion are considered as etiological factors in this progressive lesion.
