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Biomed Res Int ; 2014: 296053, 2014.
Article in English | MEDLINE | ID: mdl-25050337

ABSTRACT

The aim of the study was the evaluation of myorelaxant action of bee venom (BV) ointment compared to placebo. Parallel group, randomized double blinded trial was performed. Experimental group patients were applying BV for 14 days, locally over masseter muscles, during 3-minute massage. Placebo group patients used vaseline for massage. Muscle tension was measured twice (TON1 and TON2) in rest muscle tonus (RMT) and maximal muscle contraction (MMC) on both sides, right and left, with Easy Train Myo EMG (Schwa-medico, Version 3.1). Reduction of muscle tonus was statistically relevant in BV group and irrelevant in placebo group. VAS scale reduction was statistically relevant in both groups: BV and placebo. Physiotherapy is an effective method for myofascial pain treatment, but 0,0005% BV ointment gets better relief in muscle tension reduction and analgesic effect. This trial is registered with Clinicaltrials.gov NCT02101632.


Subject(s)
Bee Venoms/administration & dosage , Bee Venoms/therapeutic use , Muscle Relaxation/drug effects , Skin/drug effects , Temporomandibular Joint Disorders/drug therapy , Temporomandibular Joint Disorders/physiopathology , Administration, Topical , Adult , Bee Venoms/pharmacology , Double-Blind Method , Electromyography , Female , Humans , Male , Masseter Muscle/drug effects , Masseter Muscle/physiology , Muscle Tonus/drug effects , Muscle Tonus/physiology , Pain Measurement , Placebos , Rest/physiology , Young Adult
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