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Curr Med Chem ; 18(14): 2045-59, 2011.
Article in English | MEDLINE | ID: mdl-21517770

ABSTRACT

Fullerenes as a unique class of carbon allotropes have been studied extensively for their distinctive material properties and potential technological applications, including those in biology and medicine. Since a major focus in the latter has been on drug development and formulation, in this paper we highlight some representative studies related to such a focus, including the use of fullerenes for drug-like functions and for their improving the formulation of established drugs. Also discussed are some other potential medically relevant applications of fullerenes, such as their serving as potent agents in photodynamic therapy and magnetic imaging.


Subject(s)
Fullerenes/therapeutic use , Magnetic Resonance Imaging/methods , Nanomedicine/methods , Animals , Anti-HIV Agents/chemistry , Anti-HIV Agents/therapeutic use , Contrast Media , Drug Carriers/chemistry , Free Radical Scavengers/chemistry , Free Radical Scavengers/therapeutic use , Fullerenes/chemistry , HIV/drug effects , HIV Infections/drug therapy , Humans , Melanoma/drug therapy , Models, Molecular , Nanostructures/therapeutic use , Photochemotherapy/methods , Photosensitizing Agents/chemistry , Photosensitizing Agents/therapeutic use
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