ABSTRACT
Heart rate variability (HRV) was assessed on 24 hour Holter ECG recordings from 32 healthy persons and 54 patients with paroxysmal atrial fibrillation (AF) of different etiology (hypertension, ischemic heart disease, rheumatic mitral valve disease, idiopathic AF) aged 45-73 years. Nocturnal, diurnal and 24 hour HRV was measured. Time and frequency domain HRV measures were lower in patients with AF and underlying heart disease compared with healthy persons and for most of the parameters with patients with idiopathic AF (p<0,05). Patients with idiopathic AF compared with healthy persons had higher values of high frequency power during nighttime (p<0.05), what reflected activation of parasympathetic nervous system in this category of patients.
Subject(s)
Atrial Fibrillation/physiopathology , Circadian Rhythm , Heart Rate , Aged , Atrial Fibrillation/etiology , Electrocardiography, Ambulatory , Female , Humans , Male , Middle Aged , Parasympathetic Nervous System/physiopathologyABSTRACT
The diagnostic effectiveness of X-ray radionuclide and ultrasound determination of portal blood flow and the impact of different treatments on the blood flow were evaluated in 76 patients with hepatic cirrhosis. The treatment regimens were used propranolol (Group 1), isosorbide-5-mononitrate (monosan) (Group 2), and a combined therapy with propranolol in combination with diuretics and a course of intravenous laser irradiation (Group 3). In terms of both clinical and laboratory parameters and the status of portal circulation, the highest effect was observed in the patients receiving the combined therapy.
Subject(s)
Hypertension, Portal/diagnostic imaging , Hypertension, Portal/therapy , Isosorbide Dinitrate/analogs & derivatives , Liver Cirrhosis/diagnostic imaging , Liver Cirrhosis/therapy , Antihypertensive Agents/therapeutic use , Humans , Hypertension, Portal/drug therapy , Isosorbide Dinitrate/therapeutic use , Laser Therapy , Liver Cirrhosis/drug therapy , Propranolol/therapeutic use , Ultrasonography, Doppler , Vasodilator Agents/therapeutic useABSTRACT
AIM: To assess effect of radio frequency catheter ablation (RFCA) on heart rate variability (HRV) in patients with supraventricular tachyarrhythmias (SVT). METHODS: Spectral analysis of HRV on 5-minute ECG strips was carried out in 19 patients with SVT before and 2 days after RFCA. RESULTS: Both total and high frequency power significantly decreased (p<0,05) after RFCA in supine and orthostatic positions. Significant decrease of low frequency power occurred after RFCA in orthostatic position. CONCLUSION: In patients with SVT RFCA alters autonomic regulation of chronotropic function of the heart. Sympathetic and parasympathetic influences on the chronotropic function of the heart are attenuated in early period after the procedure.
