Environmental life cycle assessment of nutraceuticals: A case study on methylcobalamin in different packaging types.

The growing production of pharmaceuticals and nutraceuticals, e.g., methylcobalamin supplements, improves the health of people. This study assesses the environmental footprint of chewable methylcobalamin supplements in four packaging types: blister packs or bottles made of HDPE, PET, or glass. A cradle-to-grave life cycle assessment is conducted to evaluate the supply to Belgian consumers of the recommended daily dose of methylcobalamin supplementation (1.2 mg) in case of deficiency. The impact of methylcobalamin manufacturing in major producing countries (China as baseline and France) is analyzed based on detailed synthesis modeling of data points coming from patents. The overall carbon footprint (CF) is dominated by the transport of consumers to the pharmacy and methylcobalamin powder manufacturing in China (while its mass share per supplement is only 1 %). The impact is the lowest for supplements in HDPE bottles (6.3 g CO2 eq) and 1 %, 8 %, and 35 % higher for those in PET bottles, glass bottles, and blister packs, respectively. Tablets in blister packs have for other investigated impact categories (fossil resource footprint (FRF); acidification; eutrophication: freshwater, marine, and terrestrial; freshwater ecotoxicity; land use; and water use) the highest footprint and those in HDPE and PET bottles for most the lowest. The CF of methylcobalamin powder manufacturing in France is 22 % lower than in China (2.7 g CO2 eq), while the FRF is similar in both locations (26-27 kJ). The FRF and the difference in the CF are chiefly due to energy use and solvent production emissions. Similar trends as the CF are found for other investigated impact categories. Valuable conclusions are drawn for environmental studies on pharmaceuticals and nutraceuticals: (i) including accurate data on consumer transport, (ii) using more environmentally-friendly active ingredients, (iii) choosing appropriate packaging types considering multiple aspects: convenience, environmental footprint, etc., and (iv) providing a holistic picture through assessing various impact categories.

Impacts of human activities on the supply of marine ecosystem services: A conceptual model for offshore wind farms to aid quantitative assessments.

Increased pressures from human activities may cause cumulative ecological effects on marine ecosystems. Increasingly, the study of ecosystem services is applied in the marine environment to assess the full effects of human activities on the ecosystem and on the benefits it provides. However, in the marine environment, such integrated studies have yet to move from qualitative and score-based to fully quantitative assessments. To bridge this gap, this study proposed a 4-tiered method for summarizing available knowledge and modelling tools to aid in quantitative assessments of ecosystem services supply. First, the ecosystem functioning mechanisms underlying the supply of services are conceptually mapped. Second, the impacts of the human activity of interest are summarized and linked to the first conceptual model in a case-specific model of ecosystem services supply. Third, indicators are selected that would best represent changes in the most important parameters of the conceptual model in a quantitative manner. Fourth, the knowledge gained in the previous steps is used to select models that are most useful to quantify changes in ecosystem services supply under the human pressure of interest. This approach was applied to the case study of offshore wind energy in the Belgian part of the North Sea, which is one of the most rapidly expanding industries in the marine environment globally. This study provides a useful tool to proceed towards quantification of marine ecosystem services, highlighting the need for a fully integrated approach to developing environmental impact assessment tools.

Towards a comprehensive sustainability methodology to assess anthropogenic impacts on ecosystems: Review of the integration of Life Cycle Assessment, Environmental Risk Assessment and Ecosystem Services Assessment.

Nowadays, a variety of methodologies are available to assess local, regional and global impacts of human activities on ecosystems, which include Life Cycle Assessment (LCA), Environmental Risk Assessment (ERA) and Ecosystem Services Assessment (ESA). However, none can individually assess both the positive and negative impacts of human activities at different geographical scales in a comprehensive manner. In order to overcome the shortcomings of each methodology and develop more holistic assessments, the integration of these methodologies is essential. Several studies have attempted to integrate these methodologies either conceptually or through applied case studies. To understand why, how and to what extent these methodologies have been integrated, a total of 110 relevant publications were reviewed. The analysis of the case studies showed that the integration can occur at different positions along the cause-effect chain and from this, a classification scheme was proposed to characterize the different integration approaches. Three categories of integration are distinguished: post-analysis, integration through the combination of results, and integration through the complementation of a driving method. The literature review highlights that the most recurrent type of integration is the latter. While the integration through the complementation of a driving method is more realistic and accurate compared to the other two categories, its development is more complex and a higher data requirement could be needed. In addition to this, there is always the risk of double-counting for all the approaches. None of the integration approaches can be categorized as a full integration, but this is not necessarily needed to have a comprehensive assessment. The most essential aspect is to select the appropriate components from each methodology that can cover both the environmental and socioeconomic costs and benefits of human activities on the ecosystems.

Sustainability assessment of organic waste management in three EU Cities: Analysing stakeholder-based solutions.

This study focuses on a comprehensive sustainability assessment of the management of the organic fraction of municipal solid waste in Ghent (Belgium), Hamburg (Germany) and Pécs (Hungary). A sustainability assessment framework has been applied to analyse social, environmental, and economic consequences at the midpoint level (25 impact categories) and at the endpoint level (5 areas-of-protection). For each case study, the reference scenario was analysed, along with three solutions to improve the sustainability performance, which were selected and developed with the collaboration of local stakeholders. The solutions focus on food waste prevention, collection (increasing separate collection and household composting) and/or valorisation treatment (insect breeding, bioplastic production and improvement of centralised treatment). The results show that food waste prevention results in substantial improvements in all areas of protection when a significant quantity of food is saved. Solutions proposing innovative treatments such as insect breeding do not show clear improvements at the endpoint level, given current technology development level, but appear promising for some categories such as Revenues, Ecotoxicity, Land Use or Particulate Matter if the substituted products compensate the impact of the treatment (e.g., energy and water use). Enhancing the separate collection of organic waste can improve sustainability, but trade-offs may arise, e.g., decreased environmental savings from energy recovery at incineration. For this, the influence of the electricity mix (more or less decarbonised) should be carefully considered in future studies. The application of the solutions proposed to other cities should also consider potential bottlenecks such as legislation barriers, public acceptance, or management costs.

Development of a life cycle impact assessment framework accounting for biodiversity in deep seafloor ecosystems: A case study on the Clarion Clipperton Fracture Zone.

The transformation of ecosystems is known to be a major driver of biodiversity loss. Consequently, supporting tools such as life cycle assessment methods (LCA) include this aspect in the evaluation of a product's environmental performance. Such methods consist of quantifying input and output flows to assess their specific contributions to impact categories. Therefore, land occupation and transformation are considered as inputs to assess biodiversity impacts amongst others. However, the modelling of biodiversity impact in deep seafloor ecosystems is still lacking in LCA. Most of the LCA methods focus on terrestrial biodiversity and none of them can be transposed to benthic deep sea because of knowledge gaps. This manuscript proposes a LCA framework to assess biodiversity impacts in deep seafloor ecosystems. The framework builds upon the existing methods accounting for biodiversity impacts in terrestrial and coastal habitats. A two-step approach is proposed, assessing impacts on regional and on global biodiversity. While the evaluation of regional biodiversity impacts relies only on the benthic communities' response to disturbance, the global perspective considers ecosystem vulnerability and scarcity. Those provide additional perspective for the comparison of impacts occurring in different ecosystems. The framework is operationalised to a case study for deep-sea mining in the Clarion Clipperton Fractures Zone (CCZ). Through the large variety of data sources needed to run the impact evaluation modelling, the framework shows consistency and manages the existing limitations in the understanding of deep seafloor ecosystems, although limitations for its application in the CCZ were observed mainly due to the lack of finer scaled habitat maps and data on connectivity. With growing interest for commercial activities in the deep sea and hence, increased environmental research, this work is a first attempt for the implementation of LCA methods to deep-sea products.

Quantitative sustainability assessment of household food waste management in the Amsterdam Metropolitan Area.

Food waste represents the largest fraction of the municipal solid waste generated in Europe and its management is associated to suboptimal performance in environmental, health, and social dimensions. By processing detailed multi-fold local data as part of a comprehensive and broadly understandable sustainability framework, this study quantifies the environmental and socio-economic impacts of household food waste management in the Amsterdam Metropolitan Area based on priorities set by local stakeholders. Five alternative short-term management options have been assessed against the current system, relying on poor separate collection and incineration. Four options involve separate collection of food waste followed by biological treatments (home/centralised composting and anaerobic digestion) while one involves a mix of separate collection and centralised mechanical-biological treatment followed by anaerobic digestion. Among these, separate collection followed by anaerobic digestion coupled with effective nutrient and energy recovery is, according to our findings, the preferred option to improve the sustainability of the current system in all dimensions considered, except for the economic pillar due to the collection costs. Home and centralised composting as well as mechanical-biological treatment are associated to more adverse impacts based on our findings. The study informs local stakeholders and authorities on the potential consequences of their options, thereby allowing them to make sound choices for a future waste and circular economy strategy.

Accounting for land use in life cycle assessment: The value of NPP as a proxy indicator to assess land use impacts on ecosystems.

Terrestrial land and its resources are finite, though, for economic and socio-cultural needs of humans, these natural resources are further exploited. It highlights the need to quantify the impact humans possibly have on the environment due to occupation and transformation of land. As a starting point of this paper (1(st) objective), the land use activities, which may be mainly socio-culturally or economically oriented, are identified in addition to the natural land-based processes and stocks and funds that can be altered due to land use. To quantify the possible impact anthropogenic land use can have on the natural environment, linked to a certain product or service, life cycle assessment (LCA) is a tool commonly used. During the last decades, many indicators are developed within the LCA framework in an attempt to evaluate certain environmental impacts of land use. A second objective of this study is to briefly review these indicators and to categorize them according to whether they assess a change in the asset of natural resources for production and consumption or a disturbance of certain ecosystem processes, i.e. ecosystem health. Based on these findings, two enhanced proxy indicators are proposed (3(rd) objective). Both indicators use net primary production (NPP) loss (potential NPP in the absence of humans minus remaining NPP after land use) as a relevant proxy to primarily assess the impact of land use on ecosystem health. As there are two approaches to account for the natural and productive value of the NPP remaining after land use, namely the Human Appropriation of NPP (HANPP) and hemeroby (or naturalness) concepts, two indicators are introduced and the advantages and limitations compared to state-of-the-art NPP-based land use indicators are discussed. Exergy-based spatially differentiated characterization factors (CFs) are calculated for several types of land use (e.g., pasture land, urban land).

Environmental sustainability assessment of a microalgae raceway pond treating aquaculture wastewater: From up-scaling to system integration.

The environmental sustainability of aquaculture wastewater treatment by microalgal bacterial flocs (MaB-flocs) in an outdoor raceway pond was analyzed using life cycle assessment. Pikeperch aquaculture wastewater treated at pilot scale (Belgium; 28m(2)) and industrial scale (hypothetical up-scaling; 41 ponds of 245m(2)) were compared. The integration of the MaB-floc raceway pond in a broader aquaculture waste treatment system was studied, comparing the valorisation of MaB-flocs as shrimp feed and as biogas. Up-scaling improves the resource footprint of the plant (848MJex,CEENEkg(-1) MaB-floc TSS at pilot scale and 277MJex,CEENEkg(-1) MaB-floc TSS at industrial scale) as well as its carbon footprint and eutrophication potential. At industrial scale, the valorisation of MaB-flocs as shrimp feed is overall more sustainable than as biogas but improvements should be made to reduce the energy use of the MaB-floc raceway pond, especially by improving the energy-efficiency of the pond stirring system.