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Georgian Med News ; (274): 152-158, 2018 Jan.
Article in Russian | MEDLINE | ID: mdl-29461245

ABSTRACT

This study investigates the morphological structure of lungs, liver and kidneys of the experimental animals. To reproduce the inflammation in maxilla-facial region under the periosteum of guinea pigs' mandible a suspension of S.aureus was inoculated. The infected site was exposed by a constant electric current of positive polarity of 5-10 µA strength. Allergotests were used to determine the level of sensitization. Structural changes in the organs were determined by microscopic examination. The results of the study showed that as the contact with the antigen increased, the number of positive allergic tests also increased. Histologically, a generalized damage to the microstructure of the internal organs, depending on the degree of bacterial sensitization of the animals was observed.


Subject(s)
Kidney/immunology , Liver/immunology , Lung/immunology , Maxilla/immunology , Staphylococcal Infections/immunology , Staphylococcus aureus/immunology , Allergens/pharmacology , Animals , Antigens, Bacterial/pharmacology , Bacterial Translocation/immunology , Electric Stimulation , Guinea Pigs , Immunization/methods , Kidney/microbiology , Kidney/pathology , Kidney/ultrastructure , Liver/microbiology , Liver/pathology , Liver/ultrastructure , Lung/microbiology , Lung/pathology , Lung/ultrastructure , Male , Maxilla/microbiology , Maxilla/pathology , Staphylococcal Infections/microbiology , Staphylococcal Infections/pathology , Staphylococcus aureus/pathogenicity
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