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1.
Rev Sci Instrum ; 85(2): 02A721, 2014 Feb.
Article in English | MEDLINE | ID: mdl-24593455

ABSTRACT

The emittance of the compact microwave ion source for low energy application was investigated. The source structure was slightly modified from the previously reported version. The extraction apertures of 3 mm and 4 mm were used to evaluate the emittance. It was found that the normalized emittance of the present ion source ranged from 6 × 10(-8) m rad (3 mm extraction aperture) to 2 × 10(-7) m rad (4 mm extraction aperture), which are similar to that of the original ion source.

2.
Pathol Int ; 60(4): 326-9, 2010 Apr.
Article in English | MEDLINE | ID: mdl-20403036

ABSTRACT

A very rare case of necrotizing sialometaplasia of the parotid gland associated with angiocentric T-cell lymphoma was described. A 66-year-old male had left neck and pharyngeal masses and biopsy specimen showed a monotonous proliferation of atypical lymphoid cells with massive necrosis in the parotid gland. Angiocentric pattern or vascular invasion by the lymphoid cells was observed and the involved parotid gland exhibited squamous metaplasia of the ducts and acini; necrotizing sialometaplasia. Immunohistochemical analysis revealed a cytotoxic T-cell phenotype of the lymphoid cells (CD3+, CD4-, CD5+, CD8+, CD56-, Granzyme B+, TIA-1+, Perforin-) but in situ hybridization showed no relation to Epstein-Barr virus. Although necrotizing sialometaplasia is relatively rare in the parotid gland, angiocentric T-cell lymphoma should be considered for a causative condition of necrotizing sialometaplasia.


Subject(s)
Lymphoma, T-Cell/pathology , Neovascularization, Pathologic/pathology , Parotid Gland/pathology , Sialometaplasia, Necrotizing/pathology , Aged , Biomarkers, Tumor , Humans , Immunohistochemistry , Lymphoma, T-Cell/complications , Male , Neovascularization, Pathologic/complications , Sialometaplasia, Necrotizing/complications
3.
Breast Cancer ; 14(2): 239-44, 2007.
Article in English | MEDLINE | ID: mdl-17485912

ABSTRACT

We report a case of primary giant cell malignant fibrous histiocytoma (GCMFH) of the breast. A 56-year-old Japanese woman presented with a firm mass in the right breast. Mammography and ultrasonography revealed a well-circumscribed and lobulated mass in the upper outer quadrant of the right breast, indicative of a benign breast tumor or mucinous carcinoma. Magnetic resonance imaging revealed a restricted breast tumor without intraductal spread. Computed tomography and bone scintigraphy found no sites of distant metastases. Fine needle aspiration biopsy showed several clusters of atypical cells associated with numerous multinucleated giant cells. Breast-conserving surgery with axillary lymph nodes dissection was performed. Histological examination showed primary GCMFH of the breast. No metastases were identified in any of the 15 left axillary lymph nodes resected and surgical margins were free from tumor cells. The tumor was negative for both estrogen and progesterone receptor. Neither adjuvant chemoendocrine therapy nor postoperative radiotherapy was given, and the patient has remained disease free for 30 months postoperatively. To our knowledge, only 30 cases of primary MFH of the breast have been reported in the literature.


Subject(s)
Breast Neoplasms/pathology , Giant Cell Tumors/pathology , Histiocytoma, Malignant Fibrous/pathology , Breast Neoplasms/surgery , Diagnostic Imaging , Female , Giant Cell Tumors/surgery , Histiocytoma, Malignant Fibrous/surgery , Humans , Middle Aged
4.
Int J Eat Disord ; 38(4): 383-5, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16231363

ABSTRACT

OBJECTIVE: The extent of renal damage over long-term binge/purges has not been well documented in bulimia nervosa (BN). METHOD: We describe a 52-year-old woman with longstanding BN subsequent to an 8-year history of anorexia nervosa (AN). RESULTS: The patient showed chaotic binge/purges and chronic severe hypokalemia after recovery from AN at age 26 years, and renal biopsy showed juxtaglomerular hyperplasia, which was diagnosed as pseudo-Bartter's syndrome. DISCUSSION: Over the following 26 years, the patient's eating behaviors remained chaotic, and her renal function gradually deteriorated. After the patient died of pneumonia and sepsis at age 52 years, autopsy of her kidney showed chronic interstitial nephritis, proximal tubular swelling, and diffuse glomerular sclerosis, suggesting chronic glomerular injury associated with long-term binge/purges. To our knowledge, this is the first case report of a patient with BN with long-term binge/purges who developed an eventual "end-stage kidney" characterized by hypokalemic nephropathy and diffuse glomerulosclerosis.


Subject(s)
Bulimia/complications , Kidney Failure, Chronic/etiology , Adult , Atrophy , Bulimia/diagnosis , Bulimia/pathology , Bulimia/psychology , Fatal Outcome , Female , Follow-Up Studies , Glomerulosclerosis, Focal Segmental/diagnosis , Glomerulosclerosis, Focal Segmental/etiology , Glomerulosclerosis, Focal Segmental/pathology , Glomerulosclerosis, Focal Segmental/psychology , Humans , Hyperplasia , Hypokalemia/diagnosis , Hypokalemia/etiology , Hypokalemia/pathology , Hypokalemia/psychology , Juxtaglomerular Apparatus/pathology , Kidney/pathology , Kidney Failure, Chronic/diagnosis , Kidney Failure, Chronic/pathology , Kidney Failure, Chronic/psychology , Kidney Function Tests , Middle Aged , Nephritis, Interstitial/diagnosis , Nephritis, Interstitial/etiology , Nephritis, Interstitial/pathology , Nephritis, Interstitial/psychology
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