ABSTRACT
Seven human urinary stones were collected from urinary bladders of patients hailing from Istanbul, Turkey. Their XRD, EDX, FT-IR and FT-Raman spectra as well as SEM images have been recorded to determine their chemical compositions, morphologies, crystal structures, and crystallite sizes. XRD and vibrational (FT-IR and FT-Raman) analyses indicate that six out of the seven stones have identical contents. The ratios of organic and inorganic contents of the stones have been determined by their thermogravimetric analyses. The stones have been found to contain calcium oxalate monohydrate and apatite as the major components.
Subject(s)
Urinary Calculi/pathology , Vibration , Crystallization , Humans , Spectrometry, X-Ray Emission , Spectroscopy, Fourier Transform Infrared , Spectrum Analysis, Raman , Thermogravimetry , Turkey , Urinary Calculi/ultrastructure , X-Ray DiffractionABSTRACT
Fenofibrate, a fibric acid derivative, is used to treat diabetic dyslipidemia, hypertriglyceridemia, and combined hyperlipidemia alone or in combination with statins. Rhabdomyolysis is defined as a pathological condition of skeletal muscle cell damage leading to the release of toxic intracellular material into the circulation. Its major causes include trauma, ischemia, toxins, metabolic disorders, infections, and drugs. Rhabdomyolysis associated with fenofibrate is extremely rare. In nearly all of the presented cases, there was a predisposing factor for rhabdomyolysis such as diabetes, older age, renal insufficiency, and hypothyroidism. Here, we report a nondiabetic, nonhypothyroidic young female patient without any known prior renal disease presenting with acute renal failure developing after fenofibrate treatment.
Subject(s)
Acute Kidney Injury/etiology , Fenofibrate/adverse effects , Hypolipidemic Agents/adverse effects , Rhabdomyolysis/chemically induced , Rhabdomyolysis/complications , Adult , Creatine Kinase/blood , Female , HumansABSTRACT
Results of the first 175 laparoscopic cholecystectomies performed at our hospital over the last 18 months were reviewed. In 17 (9.7%) of cases, due to operatory complications, and in some cases due to instrumental deficiencies, we were obliged to perform conventional laparotomy. In 8 patients, we performed simultaneous alternative surgery during laparoscopy. Our results were satisfactory, with no important complications, no re-operations and only 6.2% of minor complications. Hospital stay was low (2.5 days), and after 10 days patients returned to normal life.
