ABSTRACT
The World Health Organization defines primary intraosseous squamous cell carcinoma (PIOSCC) as a squamous cell carcinoma (SCC) arising primarily within the jaws and having no connection with the oral mucosa. Here, we report a case of PIOSCC in which it was difficult to differentiate the condition from pericoronitis of an impacted maxillary wisdom tooth. The patient was a 27-year-old pregnant woman with a pain in the right maxillary wisdom tooth. The pain was diagnosed as pericoronitis of the right maxillary wisdom tooth, and the tooth was extracted under local anesthesia. During extraction, soft tissue was observed in the coronal part of the tooth, and it was diagnosed as SCC arising in a dentigerous cyst. Because the tumor may still be present, surgical resection was performed under general anesthesia. There has been no recurrence or metastasis at the 1-year follow-up. This case was histopathologically considered from being a benign odontogenic tumor to a malignant tumor. However, it revealed an extensive aberrant type and invasion equivalent to SCC. Thus, the histopathological diagnosis was PIOSCC arising from a dentigerous cyst. Although advanced cases of PIOSCC have been published, diagnosis of PIOSCC in the early stages is rare. In this case, we diagnosed pericoronitis of an impacted maxillary wisdom tooth and extracted the tooth. Therefore, we discovered it accidentally. In the early stages, diagnosis can be difficult both clinically and histopathologically.
ABSTRACT
OBJECTIVE: This study evaluated the condition of mandibular cancellous and cortical bone on computed tomography (CT) images in order to investigate its relationship with the incidence of neurosensory disturbances (NSD) in the mental nerve region after bilateral sagittal splitting ramus osteotomy (BSSRO). METHODS: BSSRO was performed on 58 lateral mandibles in 29 patients. From preoperative CT images, the width endpoints of the transversal bone were measured in region I immediately inferior to the mandibular foramen, region II in the mandibular angle region, and region III distal to the lower second molar. The incidence of NSD immediately after surgery and the residual NSD rate at 1, 3, and 6 months after surgery were investigated. The correlation between incidence of NSD in the mental nerve region and each transversal bone width endpoint immediately after and at 6 months after surgery was also comparatively evaluated. RESULTS: The overall incidence of NSD immediately after surgery was 67.2% (39/58 sides) and the overall residual NSD rate at 1, 3, and 6 months after surgery was 53.4% (31/58 sides), 31.0% (18/58 sides), and 17.2% (10/58 sides), respectively. No significant differences were observed for any width endpoints of the transversal bone measured at regions I or III, but the transversal width of the entire mandible was significantly different in region II between patients with and without NSD at 6 months after surgery (p < 0.05). CONCLUSION: These findings demonstrate that the transversal width of the entire mandible may be an important factor in predicting NSD incidence.
ABSTRACT
OBJECTIVE: The radical anion of oxygen (O(-)) is extremely oxidative and shows high reactivity. In this study, the antibacterial activity of water super-oxidised water containing high concentration of O(-) (O(-)-water) was tested against cultured planktonic cells of cariogenic bacteria, periodontopathic bacteria and Candida albicans. METHODS: O(-)-water was prepared using the AOE-750 (Oxy Japan Corporation, Japan) and its antibacterial activity against pure culture of Streptococcus sobrinus, Porphyromonas gingivalis, Prevotella intermedia, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum and C. albicans evaluated. Each oral microorganism (10(4) to 10(8)CFU/ml) was exposed to three concentrations of O(-)-water at room temperature or 37 degrees C for 15s to 24h. RESULTS: Exposure to O(-)-water resulted in a bactericidal effect against all cariogenic and periodontopathic bacteria tested. No significant fungicidal effect was observed on C. albicans, however. CONCLUSION: The results demonstrate that O(-)-water exerts an antibacterial effect on cariogenic and periodontopathic bacteria.
