Vertical distraction osteogenesis of a reconstructed mandible with a free vascularized fibula flap: a report of two cases.

BACKGROUND: The free vascularized fibula flap presents many advantages such as sufficient length of the bony segment, good vascularization, better quality of the bone, and a long vascular pedicle, but it is also associated with some disadvantages with regard to prosthetic rehabilitation because of its limited height. Improvement in bone height is necessary for ideal dental implant treatment of reconstructed mandibles. CASE PRESENTATION: For two squamous cell carcinoma patients, mandibular bone reconstruction was performed secondarily with the peroneal flap after tumor resection. Since the bone height was insufficient at the time of implant treatment, occlusion reconstruction by dental implant was performed after vertical distraction osteogenesis. CONCLUSIONS: Vertical distraction osteogenesis is a suitable treatment option for alveolar ridge deficiency resulting from fibula transplantation for mandibular reconstruction following tumor surgery.

Novel formation of diimidazo[1,2-a:2',1'-c]quinoxaline derivatives and their optical properties.

Reaction of 1,2-di(imidazolyl)benzene treated with n-BuLi proceeded to give diimidazo[1,2-a:2',1'-c]quinoxaline in the presence of iodine or Pd(PPh(3))(4). Blue fluorescence was observed from 3,10-diarylated diimidazoquinoxalines with high quantum yield. They were also applied to organic light-emitting devices as emitters, in which the diphenyl derivative emits a nearly pure blue light.

Relationship between facial asymmetry and masseter reflex activity.

PURPOSE: In this study, we evaluated the tonic vibration reflex (TVR) of the masseter muscles in patients with facial asymmetry. SUBJECTS AND METHODS: The study was conducted with 10 volunteers without facial asymmetry and 12 orthognathic patients with facial asymmetry. Subjects were seated in a chair and held a stimulator composed of an electric motor and an acrylic bite block between the upper and lower dentitions at facial midline, to elicit TVR. Electromyographic activity was recorded using a pair of silver electrodes affixed bilaterally with adhesive tape to the skin over the superficial masseter. The amount of mandibular deviation was measured on the frontal cephalogram. The reflex response was evaluated with the following: TVR index (%) = integral TVR x 100/ integral maximum voluntary contraction (MVC), and with the TVR ratio: integral TVR on the high MVC side/ integral TVR on the low MVC side. RESULTS: In the patient group, the average TVR index on the deviated side was significantly higher than that on the nondeviated side. In all subjects, including the control and patient groups, a negative correlation between the amount of mandibular deviation and the side-to-side difference in TVR index was seen (r = -0.536, P <.05, n = 22). In addition, patients with a lower MVC on the deviated side than on the nondeviated side showed a significantly higher TVR ratio than did the control group. CONCLUSIONS: These results suggest that the difference between the right and left reflex responses elicited by TVR might be related to frontal craniofacial morphology.