ABSTRACT
Serum gamma-GTP measurements in 11,755 Japanese men were used to test the hypothesis that drinking whisky had little or no effect on the serum level of this enzyme. We found that regular drinking was associated with significantly increased mean levels and raised percentages of high values of gamma-GTP, irrespective of the type of alcohol consumed. Moreover, heavier and more frequent drinking were associated with proportionately greater increases in gamma-GTP levels. Our data therefore refute the hypothesis that whisky drinking is not accompanied by adverse changes in the level of serum gamma-GTP.
Subject(s)
Alcoholic Beverages , Ethanol/pharmacology , gamma-Glutamyltransferase/blood , Humans , Japan , MaleABSTRACT
We studied the relation between admission after check-up and check-up frequencies of AMHTS examinees in our hospital in order to evaluate the usefulness of serial check-ups. Follow-up studies were performed on a total of 16,630 examinees and continued until March 1982. There were 558 inpatients, 3.4% of the total. The main reason for their admission was cancer, followed by diabetes mellitus and chronic hepatitis. It was shown that the admission rates of examinees decreased as the check-up frequencies increased the examinees under 60 years old, but not for those over 60 years of age. In addition, both admission and cancer rates of AMHTS examinees decreased on the whole as their check-up frequencies increased.
