Biomechanical Comparison of the Simple Suture Technique, Meniscal Matrix-Assisted Repair, and a Novel Meniscus Cap Suture Technique for Complex Meniscal Repair.

Background: Meniscal repair is the gold standard for simple morphology tears. However, when the morphology and chronicity of the tear are less favorable, the success of the standard techniques is reduced. Purpose/Hypothesis: To compare meniscal repair augmented by a new bioresorbable implant (Meniscus Cap) versus a traditional simple suture technique and the currently available augmented repair collagen matrix meniscus wrapping technique. It was hypothesized that the Meniscus Cap suture technique would increase ultimate failure load and less displacement during cyclic loading. Study Design: Controlled laboratory study. Methods: A total of 80 fresh porcine menisci were harvested. Complex tears were created in 60 menisci, and 20 intact menisci were tested as the control group. Repairs were performed on the 60 meniscal tears using 1 of the 3 techniques (20 menisci each): an inside-out H-suture group (SS), the collagen matrix wrapping technique (CMW), and the Meniscus Cap bioresorbable implant group (CM). The menisci were subjected to 500 loading cycles from 4 to 20 N at a frequency of 1 Hz, and the total displacement was recorded. Then, the specimens underwent load to failure testing at a rate of 3.15 mm/s, and the failure mode was noted. Results: After 500 cycles of cyclic loading, there were no significant differences in displacement between the controls and CM group (0.524 vs 0.448 mm; P = .95). The displacement after the CM was significantly smaller compared with the CMW and the SS (0.448 vs 1.077 mm [P = .0009] and 0.448 vs 0.848 mm [P = .04], respectively). The ultimate load to failure was significantly greater for the controls and the CM group compared with the SS and CMW groups (controls, 1278.7 N and CM, 628.5 N vs CMW, 380.1 N and SS, 345.1 N; P < .05). The failure mode was suture breakage (suture failure) for all repairs. Conclusion: In a porcine specimen meniscal repair model, the biomechanical properties of a novel Meniscus Cap repair technique were superior to that of the simple suture and CMW techniques. Clinical Relevance: The results suggest that the Meniscal Cap repair technique may provide sufficient primary stability of the meniscal fixation even in the cases of complex meniscal tears.

Experimental Study on the Cutting Process of Single Triticale Straws.

This paper presents experimental research on cutting a single stalk of triticale straw for the production of biofuel in the process of its compaction using the piston technique. In the first stage of the experimental study of cutting single triticale straws, the variable parameters were the moisture contents of the stem equal to 10% and 40%, the offset between the blade and the counter-blade g, and the linear velocity of the knife blade V. The blade angle and rake angle were equal to α = 0° and ß = 0°. In the second stage, the variables, including the blade angle values α = 0°, 15°, 30°, and 45° and the rake angle values ß = 5°, 15°, and 30°, were introduced. Taking into account the analysis of the distribution of forces on the knife edge leading to the determination of the force quotients Fc″/Fc and Fw/Fc, and on the basis of the optimization performed and the adopted optimization criteria, the optimal knife edge angle α can be determined (at values g = 0.1 mm and V = 8 mm/s) at α ≅ 0° and the angle of attack ß within the range of 5-26°. What the value will be in this range depends on the value of the weight adopted in the optimization. The choice of their values may be decided by the constructor of the cutting device.

Experimental Study on the Mechanical Behavior of Dry Corn Stalk Cutting.

This work presents an experimental study of cutting corn stalks for thermal energy generation. The study was carried out for the values of blade angle in the range of α = 30-80°, distance between the blade and the counter-blade g = 0.1, 0.2, 0.3 mm and the velocity of the blade V = 1, 4, 8 mm/s. The measured results were used to determine shear stresses and cutting energy. The ANOVA variance analysis tool was used to determine the interactions between the initial process variables and the responses. Furthermore, the blade load-state analysis was carried out, together with determining the knife blade strength characteristic, based on the determination criteria for the strength of the cutting tool. Therefore, the force ratio Fcc/Tx was determined as the determinant of strength, and its variance characteristic in the function of the blade angle, α, was used in the performed optimization. The optimization criteria entailed the determination of such values of the blade angle, α, for which the cutting force value, Fcc, and the coefficient of knife blade strength approached the minimum value. Hence, the optimized value of the blade angle, α, within the range 40-60° was determined, depending on the assumed weight parameters for the above-mentioned criteria.

Computational methodology for drug delivery to the inner ear using magnetic nanoparticle aggregates.

BACKGROUND AND OBJECTIVE: The main goal of the proposed study is to improve the efficiency of the ear treatment via targeted drug delivery to the inner ear, i.e. the cochlea. Although pharmacotherapy has been proposed as a solution to prevent damage or restore functionality to hair cells, the main challenge in such treatments is ensuring adequate drug delivery to the cells. To this end, we present a methodology for the evaluation of the magnetic forces needed to move magnetic particle nanorobots (abbreviated as MNP) and their aggregates through the cochlea round window membrane (RWM). METHODS: The FEM - Lagrangian-Eulerian approach (Abaqus software) was used to determine the specific parameters of movement of the nanoparticles crossing the RWM. This method results in a high consistency of FEM simulations and in-vivo experimental results in regards to the required magnetic force during the movement of spherical nanoparticles with a given viscosity ηave. Based on the analysis of the experimental studies found in subject literature, the sizes of the MNPs and their aggregates able to cross RWM with and without the application of magnetic force FM have been determined. RESULTS: The present work accounts for both the experimental and theoretical aspects of these investigations. Presented research confirms the definite usability of the Lagrange-Euler method for the precise determination of the required magnetic force value FM to control the accelerated motion of MNP aggregates of complex shapes through RWM. It is possible to determine the predominant parameters with a precision of less than 5% for single-layer aggregates and spatial aggregates crossing the RWM. It can be concluded that the MNPs and their aggregates should not be larger than 500-750 nm to cross the RWM with high velocities of penetration close to 800 nm/s for magnetic forces of hundreds 10-14 Newtons. CONCLUSIONS: The proposed Lagrangian-Eulerian approach is capable of accurately predicting the movement parameters of MNP aggregates of irregular shape that are close to the experimental test cases. The presented method can serve as a supplementary tool for the design of drug delivery systems to the inner ear using MNPs.

Designing of the Electromechanical Drive for Automated Hot Plate Welder Using Load Optimization with Genetic Algorithm.

Drive and conveyor belts are widely used in the mining and processing industry. One of the types often used is the belt with a cross-section and a diameter of several millimeters, made of weldable thermoplastic elastomer. Their production process requires the joining of the ends to obtain a closed loop. This operation is often performed by butt welding using the hot plate method. Taking into account the industrial requirements, the authors made an effort to design the automated welding machine for this type of belt. The work that had been conducted was finished with the implementation of the device for serial belt production. One of the stages of the design process of the welding machine consisted of developing a solution for the electromechanical drive system. The paper presents a design and the selection of the key components of the drive system, in particular, the electrical executive elements. Firstly, on the basis of the functional requirements of individual working mechanisms, the kinematic structure of the drives was developed, and the influence of the workload on power consumption was described. Then, using known technological parameters, experimental research of the plasticization operation was performed. On the basis of the results obtained, a mathematical model of the correlation between the plasticization force and technological parameters was derived. Using the derived model, the optimization of the technological parameters was made by using a genetic algorithm. The work led to the choice of an effective electric motor, which is the main component of the designed drive system.

A Coupled Eulerian-Lagrangian Simulation and Tool Optimization for Belt Punching Process with a Single Cutting Edge.

The objective of this paper is to analyze the belt punching process with the use of a single cutting edge and discuss the influence of geometrical features of the piercing punch on the perforation force. Two basic shapes of the piercing punch with a single cutting edge were tested: tools with the blade pointing inside or pointing outside. The analytical models of the stress distribution in the shearing cross sections were derived for both punches. The presented model, along with the series of empirical tests and Coupled Eulerian-Lagrangian simulation, was used for finding the effective geometry of the piercing punch with a single cutting edge for the belt perforation. The geometrical parameters taken into consideration for the tool optimization were the following: angle of the blade, thickness of the wall and diameter of the piercing punch cutting edge. The obtained results show that changing these parameters has a significant influence on the perforation force necessary to execute the machining process and affects the quality of the holes in the perforated belts. The most important geometrical features of the hollow sharpened punch are the angle and the direction of the blade, which change the force distribution and, as a result, the mechanics of the process.

Comparative Analysis of Polyurethane Drive Belts with Different Cross-Section Using Thermomechanical Tests for Modeling the Hot Plate Welding Process.

The paper presents a comparative analysis of the circular and flat cross-section belts using measurements of a set of thermomechanical parameters, contributing to research about hot plate welding of drive belts. On the basis of thermogravimetric and spectrophotometric tests, information about the same chemical composition of the two belts was obtained. Dynamic thermomechanical analysis and scanning differential calorimetry provided information about a small difference between belts, which disappeared when the material was placed in a state of increased temperature and mechanical stress. On the basis of the analysis of the specific heat, thermal diffusion, density, and hardness, the values of the selected thermal properties of the belt were obtained, and a large similarity between the belts was identified. On the basis of the novel performed test cycle, it has been hypothesized that circular and flat belts made from thermoplastic polyurethane elastomer could be used interchangeably for butt-welding testing. It has also been proven that cyclic thermomechanical loads unify the properties of both materials so that multiple mechanical and thermal loads do not result in any change in the material properties of the two belts. As a consequence, changes in the weld properties after welding, compared to a solid belt, are not expected.

Magnetorheological Elastomer Stress Relaxation Behaviour during Compression: Experiment and Modelling.

Materials characterized by magnetorheological properties are non-classic engineering materials. A significant increase in the interest of the scientific community about this group of materials could be observed over the recent years. The results of research presented in this article are oriented on the examination of the said materials' mechanical properties. Stress relaxation tests were carried out on cylindrical samples of magnetorheological elastomers loaded with compressive stress, for various values of magnetic induction (B1 = 0 mT, B2 = 32 mT, B3 = 48 mT, and B4 = 64 mT) and temperature (T1 = 25 °C, T2 = 30 °C, and T3 = 40 °C). The results of these tests indicate that the stiffness of the examined samples increased along with the increase of magnetic field induction, and decreased along with the increase of temperature. On this basis, it has been determined that: the biggest stress amplitude change, caused by the influence of magnetic field, was σ0ΔB = 12.7%, and the biggest stress amplitude change, caused by the influence of temperature, was σ0ΔT = 11.3%. As a result of applying a mathematical model, it was indicated that the stress relaxation in the examined magnetorheological elastomer, for the adopted time range (t = 3600 s), had a hyperbolic decline nature. The collected test results point to the examined materials being characterized by extensive rheological properties, which leads to the conclusion that it is necessary to conduct further tests in this area.

Mathematical Model Describing the Influence of Geometrical Parameters of Multichannel Dies on the Limit Force of Dry Ice Extrusion Process.

The article presents a formulated mathematical model that enables the determination of the required compressive force in the extrusion process of dry ice employing multichannel dies. This is the main parameter in the piston-based dry ice extrusion process. The indicated model was developed for the purpose of further improvement of the energy efficiency of this extrusion process. It allows for the determination of the value of compressive force by accounting for 12 variables related to the geometrical parameters of the die and the physical characteristics of dry ice. Furthermore, the paper also provides descriptions of the empirical study methodologies together with the results. These were carried out in order to determine the difference between the results of mathematical modeling and actual measurement results. The final part of the article presents the results of the analysis of the mathematical model's sensitivity to the change of the physical characteristics of dry ice. The formulated tool may be employed to adapt the geometric parameters of the die in order to obtain the desired compressive force value and dry ice granulation with reduced energy consumption.

Minimally invasive reconstruction technique for chronic Achilles tendon tears allows rapid return to walking and leads to good functional recovery.

PURPOSE: Chronic Achilles tendon tears, including chronic ruptures with end gap over 6 cm making end-to-end suturing impossible, can be treated with autologous hamstring graft reconstruction. The primary goal of this study was to present the biomechanical and long-term clinical results of recently developed minimally invasive Achilles tendon reconstruction technique. METHODS: Minimally invasive Achilles tendon reconstruction was applied to 8 foot and ankle cadaveric specimens as well as 18 patients with chronic Achilles tendon tears. Repaired cadavers were subjected to the biomechanical testing using a cyclic loading protocol. Patients with reconstructed Achilles tendon were subjected to the clinical, functional and isokinetic tests at 12 months after the treatment. RESULTS: All of tested Achilles cadaveric specimens survived 2 loading blocks (250 cycles of 10-100 N load followed by additional 250 cycles of 10-200 N load). With three specimens, it was possible to perform the third cyclic loading block with 20-300 N load and two specimens survived the fourth block with 20-400 N load. Therefore, a mean number of 838 cycles (±178) within the range of 509-1000 was recorded. Two specimens which survived all 1000 cycles were pulled to failure at 25 mm/s rate. The results obtained in the load to failure testing were as follows: 398 N and 608 N of maximum load. The results of functional heel rise endurance test and single leg hop for distance test indicated a decrease in the endurance and strength of the injured limb. However, the results of the weight-bearing lunge tests indicated no tendency for elongation of the Achilles tendon. A comparative analysis of the isokinetic test results for the non-injured and injured limb was revealed no statistically significant differences for every isokinetic test (n. s.), with significant difference for isometric strength parameters (p = 0.0006). CONCLUSIONS: The results of the biomechanical tests as well as 1-year extensive functional, clinical and isokinetic results of the minimally invasive technique for chronic Achilles tendon tears are encouraging. Patients returned to their normal physical activity, including sport pre-injury level in most cases. LEVEL OF EVIDENCE: III.