ABSTRACT
La Sarcoidosis es una enfermedad multisistémica que se caracteriza histológicamente por existencia de granulomas epiteliodes sin necrosis caseosa. Laafectación cutánea aparece en un 20-35% de los pacientes con sarcoidosis sistémica pero también puede aparecer como única manifestación de laenfermedad. Describimos un paciente afecto de sarcoidosis cutánea sin afectación sistémica. Las lesiones cutáneas no respondieron tras varios tratamientostópicos y sistémicos y finalmente respondieron a metotrexato. Revisamos las diferentes opciones en el tratamiento de la sarcoidosis cutánea (AU)
Sarcoidosis is a multisystemic disorder characterized histollogically by epithelioid granulomas without caseating necrosis. Cutaneous involvementoccurs in 20-35% of patients with systemic sarcoidosis and may occur without systemic involvement. A patient with cutaneous sarcoidosis, withoutsystemic involvement is reported. Cutaneous lesions do not responsive to various forms of topical and systemic treatment and finally were responsiveto metotrexate. We review treatment options for cutaneous sarcoidosis (AU)
Subject(s)
Humans , Sarcoidosis/drug therapy , Skin Diseases/drug therapy , Methotrexate/therapeutic use , Granuloma/drug therapy , Diagnosis, DifferentialABSTRACT
The Sweet syndrome or acute febrile neutrophilic dermatosis is a well characterized cutaneous disease from a clinical and histological point of view and is frequently associated with systemic diseases. Prognosis is favorable with good response to corticoid therapy. A well documented case of Sweet syndrome associated with an outbreak of Crohn's disease with peculiar good therapeutic response is reported.
