Voltage-sensitive dye imaging of the visual cortices responding to electrical pulses at different intervals in mice in vivo.

Properties of the neural responses to electrical stimulus pulses delivered at various inter-pulse intervals were examined in the visual cortices of mice in vivo, with utilizing the voltage-sensitive dye imaging technique. Our experimental results provided the relationships between the inter-pulse intervals and the stimulus-evoked transient depolarizations, which may offer insight into the design of effective and efficient stimulation for cortical visual prostheses.