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1.
Opt Express ; 30(9): 13959-13967, 2022 Apr 25.
Article in English | MEDLINE | ID: mdl-35473149

ABSTRACT

Dispersion impairments are a well-known limitation in data center communications, limiting both the usable data rates and reaches. Several companies today adopt silicon photonics as a core technology in their transceiver products. This presents an opportunity for silicon photonics-based dispersion management technologies to be integrated with the transceiver transmitter or receiver. In this manuscript, we present a ring-resonator based, tunable dispersion compensation device, providing dispersion ranging as wide from + 12.9 × 103ps/nm to -12.3 × 103ps/nm. Thermo-optic tuning from 20°C to 70°C is demonstrated to allow continuous wavelength tuning across 200 GHz. High-speed experiments using 25 Gb/s non-return-to-zero data propagating through 20 km of single mode fiber show that a significant improvement in the eye diagram is achieved after compensation with the ring-resonator device. We demonstrate a significant improvement in the BER from 10-3 to 10-11 for data rates of 25 and 25.78125 Gb/s.

2.
Sci Rep ; 11(1): 21292, 2021 Oct 28.
Article in English | MEDLINE | ID: mdl-34711919

ABSTRACT

Infrared (IR)-emitting RE doped materials have been extensively used to fabricate active components of integrated optical devices in various fields, such as fiber amplifiers, telecommunications, optoelectronics, and waveguides. Among various RE elements, trivalent erbium ions (Er 3+) are of great interest since their emissive behavior span the low loss telecommunication window of 1300-1650 nm. In this paper, we report two types of polymeric waveguide amplifiers. 8 cm long, lithographically patterned spiral waveguides provide 8 dB of gain using a 980 nm pump power of 95 mW. Gain is observed from 1530 to 1590 nm. We further report the first demonstration of polymeric waveguide amplifiers fabricated using 3D printing methods based on two-photon lithography, paving the way for rapid prototyping of active 3D printed devices and active photonic devices which may transcend planar limitations.

3.
Opt Lett ; 42(21): 4450-4453, 2017 Nov 01.
Article in English | MEDLINE | ID: mdl-29088185

ABSTRACT

We report on the design and experimental demonstration of a broadband silicon polarization beam splitter (PBS) with a high extinction ratio (ER)≥30 dB. This was achieved using triple-bent-waveguide directional coupling in a single PBS, and cascaded PBS topology. For the single PBS, the bandwidths for an ER≥30 dB are 20 nm for the quasi-TE mode, and 70 nm for the quasi-TM mode when a broadband light source (1520-1610 nm) was employed. The insertion loss (IL) varies from 0.2 to 1 dB for the quasi-TE mode and 0.2-2 dB for the quasi-TM mode. The cascaded PBS improved the bandwidth of the quasi-TE mode for an ER≥30 dB to 90 nm, with a low IL of 0.2-2 dB. To the best of our knowledge, our PBS system is one of the best broadband PBSs with an ER as high as ∼42 dB and a low IL below 1 dB around the central wavelength, and experimentally demonstrated using edge-coupling.

4.
Sci Rep ; 7(1): 9101, 2017 08 22.
Article in English | MEDLINE | ID: mdl-28831178

ABSTRACT

Ring resonators on silicon rich nitride for potential use as rare-earth doped amplifiers pumped at 1310 nm with amplification at telecommunications-band are designed and characterized. The ring resonators are fabricated on 300 nm and 400 nm silicon rich nitride films and characterized at both 1310 nm and 1550 nm. We demonstrate ring resonators exhibiting similar quality factors exceeding 10,000 simultaneously at 1310 nm and 1550 nm. A Dysprosium-Erbium material system exhibiting photoluminescence at 1510 nm when pumped at 1310 nm is experimentally demonstrated. When used together with Dy-Er co-doped particles, these resonators with similar quality factors at 1310 nm and 1550 nm may be used for O-band pumped amplifiers for the telecommunications-band.

5.
Nat Commun ; 8: 13878, 2017 01 04.
Article in English | MEDLINE | ID: mdl-28051064

ABSTRACT

CMOS platforms operating at the telecommunications wavelength either reside within the highly dissipative two-photon regime in silicon-based optical devices, or possess small nonlinearities. Bandgap engineering of non-stoichiometric silicon nitride using state-of-the-art fabrication techniques has led to our development of USRN (ultra-silicon-rich nitride) in the form of Si7N3, that possesses a high Kerr nonlinearity (2.8 × 10-13 cm2 W-1), an order of magnitude larger than that in stoichiometric silicon nitride. Here we experimentally demonstrate high-gain optical parametric amplification using USRN, which is compositionally tailored such that the 1,550 nm wavelength resides above the two-photon absorption edge, while still possessing large nonlinearities. Optical parametric gain of 42.5 dB, as well as cascaded four-wave mixing with gain down to the third idler is observed and attributed to the high photon efficiency achieved through operating above the two-photon absorption edge, representing one of the largest optical parametric gains to date on a CMOS platform.

6.
Opt Express ; 23(6): 8095-103, 2015 Mar 23.
Article in English | MEDLINE | ID: mdl-25837147

ABSTRACT

Multiplexing of optical modes in waveguides is demonstrated using coupled vertical gratings. The device utilizes sinusoidally corrugated waveguides of different widths with a period designed to multiplex information at 1.55 µm. The design, fabrication and characterization of devices is performed. Multiplexing of modes is demonstrated in optical structures which support 3 and 5 quasi-TE modes. The design utilizes counter-propagating modes in periodic structures, thus enabling the device to combine its mode division multiplexing capabilities with wavelength division multiplexing functionalities to further augment the multiplexing capacity of the device.

7.
Opt Express ; 22(9): 10408-15, 2014 May 05.
Article in English | MEDLINE | ID: mdl-24921742

ABSTRACT

A 1 by 4 wavelength division multiplexer with 0.5nm bandwidth and no free spectral range limitation is demonstrated on silicon. The device utilizes wide bandwidth filters cascaded with ring resonators in order to select specific ring resonator modes and route each resonant mode to a separate port. This technology will enable dense wavelength division multiplexing covering the C - and L - bands with up to 100 10GB/s channels separated by 100GHz to be implemented for optical interconnects applications. A 1 by 4 wavelength division multiplexer with 3dB channel bandwidths as small as 0.5nm and 1dB insertion loss are demonstrated with 16dB inter-channel crosstalk suppression. A second wavelength division multiplexer scheme with four channels, each spaced 0.5nm apart without any free spectral range limitations is also demonstrated using wide bandwidth filters centered at the same wavelength to select resonances from four different ring resonators with slightly different widths.

8.
Appl Opt ; 52(4): 613-24, 2013 Feb 01.
Article in English | MEDLINE | ID: mdl-23385898

ABSTRACT

This paper reviews recent work in the area of silicon photonic devices and circuits for monolithic and heterogeneous integration of circuits and systems on a chip. In this context, it presents fabrication results for producing low-loss silicon waveguides without etching. Resonators and add-drop distributed filters utilizing sidewall modulation fabricated in a single lithography and etching step are demonstrated. It also presents an optical pulse compressor that monolithically integrates self-phase modulation and anomalous dispersion compensation devices on a silicon chip. As an example of heterogeneous integration, we demonstrate vertical emitting metallo-dielectric nanolasers integrated onto a silicon platform. Future research directions toward large-scale photonic circuits and systems on a chip also are discussed.

9.
Opt Express ; 21(24): 29223-30, 2013 Dec 02.
Article in English | MEDLINE | ID: mdl-24514474

ABSTRACT

The simultaneous generation of second and third order dispersion is demonstrated using nonlinearly chirped silicon waveguide gratings. The nonlinearly chirped gratings are designed to generate varying signs and magnitudes of group velocity dispersion and dispersion slope. The design, fabrication, and experimental characterization of the silicon waveguide gratings are performed. Second order dispersion as high as -2.3 X 106 ps/nm²/km and third order dispersion as high as 1.2 X 105 ps/nm²/km and as low as 1.2 X 104 ps/nm²/km is demonstrated at 1.55 µm.

10.
Ultrasound Obstet Gynecol ; 38(5): 533-7, 2011 Nov.
Article in English | MEDLINE | ID: mdl-21557370

ABSTRACT

OBJECTIVE: To evaluate the degree of agreement in first-trimester nasal bone assessment in a group of sonographers before and after training, using a semi-quantitative scoring system. METHODS: Four sonographers who routinely perform first-trimester screening were first shown 46 images from both normal and trisomy 21 pregnancies. For each image, they were asked to score from 0 (disagree) to 3 (agree) on five different criteria that were deemed important in nasal-bone assessment, including image size, plane and visibility of nasal bone. A training program was then conducted, and a repeat exercise was carried out using the same 46 images. Finally, in a third exercise, images from 42 patients were presented, some having more than one image. The sonographers were required to give one overall nasal-bone score for each patient. In each exercise interobserver agreement was evaluated by intraclass correlation coefficient (ICC). RESULTS: Before training, the sonographers agreed reasonably well on the five proposed criteria (ICC, 0.752), with some disagreement on their perceived image quality. The training program further improved the agreement (ICC, 0.790), particularly on whether the nasal bone was the biggest and brightest echogenic component. Agreement was excellent when they were asked to give one overall score on the nasal bone based on multiple images from one patient (ICC, 0.929). CONCLUSION: The proposed scoring system can be used to improve consistency and reliability in first-trimester nasal-bone assessment.


Subject(s)
Down Syndrome/diagnostic imaging , Nasal Bone/diagnostic imaging , Pregnancy Trimester, First , Ultrasonography, Prenatal/methods , Down Syndrome/embryology , Female , Humans , Nasal Bone/embryology , Observer Variation , Pregnancy , Quality Assurance, Health Care , Reproducibility of Results , Surveys and Questionnaires
11.
Opt Express ; 19(3): 2401-9, 2011 Jan 31.
Article in English | MEDLINE | ID: mdl-21369058

ABSTRACT

We demonstrate an add/drop filter based on coupled vertical gratings on silicon. Tailoring of the channel bandwidth and wavelength is experimentally demonstrated. The concept is extended to implement a 1 by 4 wavelength division multiplexer with 6 nm channel separation, 3 nm bandwidth, a flat top response with < 0.8 dB ripple within the 3 dB passband, 1 dB insertion loss and 16 dB crosstalk suppression. The device is ultracompact, having a footprint < 2 X 10(-9)/2.


Subject(s)
Optical Devices , Refractometry/instrumentation , Silicon/chemistry , Telecommunications/instrumentation , Computer-Aided Design , Equipment Design , Equipment Failure Analysis , Miniaturization
12.
Br J Ophthalmol ; 94(10): 1295-9, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20829318

ABSTRACT

AIM: To compare visual outcomes between deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK). Secondarily to compare refractive outcomes, complications and graft survival between the three cohorts. METHODS: Retrospective case-control study evaluating visual acuity outcomes (VA) following DALK with complete Descemet's baring (DALKa) (modified Anwar big bubble technique--51 eyes), pre-descemetic anterior lamellar keratoplasty (DALKm) (manual technique--52 eyes) and PK (103 eyes) with mean follow-up of 13.6, 19.3 and 18.6 months, respectively. RESULTS: The common indications for surgery were corneal scars (36.4%), keratoconus (28.6%) and corneal dystrophies (13.6%). A best-corrected VA of 6/7.5 or better was achieved in 19.4% (PK), 21.6% (DALKm) and 38.5% (DALKa) of cases (p=0.02), and eyes that underwent DALKa had significantly better visual outcomes than PK (p=0.03). Complications following PK were glaucoma (15%), endothelial rejection (12%) and epithelial problems (11%); in the lamellar group, glaucoma (9%), epithelial problems (5%) and Descemet's detachment (3%) were more common. The 2-year estimated probability of graft survival was 90% for PK, 98% for DALKm and 100.0% for DALKa (p=0.35). CONCLUSIONS: Lamellar keratoplasty with complete baring of the Descemet's membrane (DALKa) gave significantly better visual outcomes compared to PK or pre-descemetic ALK and should be the preferred from of corneal replacement in corneal disorders with healthy endothelium.


Subject(s)
Corneal Diseases/surgery , Corneal Transplantation/methods , Visual Acuity/physiology , Adult , Analysis of Variance , Case-Control Studies , Corneal Diseases/physiopathology , Graft Survival , Humans , Kaplan-Meier Estimate , Postoperative Complications/etiology , Postoperative Complications/physiopathology , Refractive Errors/etiology , Refractive Errors/physiopathology , Retrospective Studies , Treatment Outcome
13.
Opt Lett ; 34(9): 1357-9, 2009 May 01.
Article in English | MEDLINE | ID: mdl-19412271

ABSTRACT

A cladding-modulated Bragg grating implemented using periodic placements of cylinders along a waveguide is proposed in a silicon-on-insulator platform. The coupling strength is varied by changing the distance between the cylinders and the waveguide. This implementation enables precise control and a wide dynamic range of coupling strengths and bandwidths that can be practically achieved for applications with specific bandwidth requirements. Modeling results are verified experimentally, and we demonstrate coupling strengths differing by 1 order of magnitude (43 and 921 per cm) with bandwidths of 8 and 16 nm, respectively. This method scheme enables weakly coupled devices with high fabrication tolerance to be realized.

14.
Br J Ophthalmol ; 93(7): 926-31, 2009 Jul.
Article in English | MEDLINE | ID: mdl-19429578

ABSTRACT

BACKGROUND: To describe the underlying molecular genetic basis, surgical management and phenotypic variation of Schnyder corneal dystrophy (SCD) identified in a four-generation Chinese family. METHODS: This is an interventional case series of 13 members from a non-consanguineous Chinese family. All patients underwent complete ophthalmological examination and slit-lamp photography. Subsequent corneal transplantations were performed (n = 3). Blood samples were taken for DNA extraction and subsequent genetic analysis. RESULTS: Genotyping indicated linkage to the locus at chromosome 1p36. Screening of the UBIAD1 gene identified a highly conserved mutation, Ser171Pro. Phenotypic variation in this large pedigree is similar to that seen in Caucasian patients. Surgical management of patients with anterior lamellar keratoplasty and deep anterior lamellar keratoplasty showed good visual outcomes. CONCLUSIONS: The S171P mutation is described for the first time in a Chinese family. This is the largest non-Caucasian pedigree described with SCD. Visual rehabilitation may be performed successfully with lamellar surgical procedures as opposed to full-thickness corneal grafts.


Subject(s)
Corneal Dystrophies, Hereditary/genetics , Point Mutation/genetics , Proteins/genetics , Adult , Aged , Aged, 80 and over , Asian People , Corneal Dystrophies, Hereditary/surgery , Corneal Transplantation , DNA Mutational Analysis , Dimethylallyltranstransferase , Female , Genetic Linkage , Genetic Predisposition to Disease , Humans , Middle Aged , Pedigree , Phenotype , Tomography, Optical Coherence , Visual Acuity
15.
Br J Ophthalmol ; 93(3): 299-304, 2009 Mar.
Article in English | MEDLINE | ID: mdl-18927226

ABSTRACT

AIM: The aim of the study was to describe the prevalence and visual outcomes of cataract surgery in an urban Asian population. METHODS: This was a population-based study of 3280 Singapore Malays aged 40-80 years (response rate 78.7%). Participants had a standardised interview and comprehensive ocular examination. Poor post-operative visual outcome was defined as visual acuity

Subject(s)
Cataract Extraction/statistics & numerical data , Adult , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Prevalence , Singapore/epidemiology , Treatment Outcome , Urban Population/statistics & numerical data , Visual Acuity
16.
Opt Lett ; 33(24): 3013-5, 2008 Dec 15.
Article in English | MEDLINE | ID: mdl-19079525

ABSTRACT

A strongly coupled, chirped Bragg grating made by sinusoidally modulating the sidewalls of a silicon waveguide is designed, fabricated, and experimentally characterized. By varying the device parameters, the operating wavelength, device bandwidth, sign (normal or anomalous), and magnitude of group-velocity dispersion may be engineered for specific photonic applications. Asymmetric Blackman apodization is best suited for maximizing the useable bandwidth while providing good ripple suppression. Dispersion values up to 7.0 x 10(5) ps/nm/km are demonstrated at 1.55 microm.

18.
Int J Oral Maxillofac Surg ; 36(9): 807-13, 2007 Sep.
Article in English | MEDLINE | ID: mdl-17630251

ABSTRACT

The aim of this retrospective study was to describe the oral procedures used in osteo-odonto-keratoprosthesis (OOKP) surgery, and the demographics and oral findings of candidate patients in Singapore. The OOKP procedure utilizes an autologous tooth-bone complex to mount a poly-methylmethacrylate optical cylinder, as an artificial cornea, stabilized by an overlying autologous buccal mucosal graft. Consecutive patients referred over 3 years for dental evaluation prior to OOKP surgery were included. A total of 21 patients underwent oral clinical and radiographic evaluation. The aetiology of blindness included Stevens-Johnson's syndrome (11 cases), chemical burns (9 cases) and multiple failed corneal grafts (1 case). Evaluation revealed that 12 patients were suitable for OOKP surgery, 8 were at risk of complication or failure and 1 had no usable teeth. Fourteen patients have undergone unilateral OOKP Stage 1 surgery successfully. Complications included fracture of a tooth from its lingual bone necessitating the harvesting of a second tooth (1 case), oronasal perforation (1 case), exposure of adjacent roots (5 teeth), lower lip paresthesia (2 cases) and submucosal scar band formation in the buccal mucosal graft donor site (10 cases). Thirteen patients have completed Stage 2 surgery, with attainment of their best possible visual potential following OOKP surgery.


Subject(s)
Alveolar Process/transplantation , Bioprosthesis , Blindness/surgery , Oral Surgical Procedures/methods , Orbital Implants , Tooth Root/transplantation , Adolescent , Adult , Blindness/rehabilitation , Bone Transplantation/methods , Cornea/pathology , Cornea/surgery , Corneal Opacity/surgery , Female , Humans , Male , Middle Aged , Ophthalmologic Surgical Procedures/methods , Osteotomy/methods , Prosthesis Design , Prosthesis Implantation/methods , Plastic Surgery Procedures/methods , Refraction, Ocular , Retrospective Studies
19.
Br J Ophthalmol ; 90(10): 1230-5, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16809384

ABSTRACT

AIM: To compare the prevalences of refractive errors in Malay, Chinese and Indian children in Malaysia and Singapore. METHODS: Children aged 7-9 years from three schools in the Singapore Cohort study of the Risk factors for Myopia (n = 1962) and similarly aged children from a random cluster sample in the metropolitan Kuala Lumpur area in the Malaysia Refractive Error Study in Children (n = 1752) were compared. Cycloplegic autorefraction was conducted in both countries. RESULTS: The prevalence of myopia (spherical equivalent of at least -0.5 diopters (D) in either eye) was higher in Singapore Malays (22.1%) than in Malays in Malaysia (9.2%; 95% confidence interval (CI) 11.2 to 14.7; p<0.001). Similarly, Singapore Chinese (40.1%) had higher prevalences than Malaysian Chinese (30.9%; 95% CI 1.5 to 16.9). Singapore Indians had a higher prevalence (34.1%) than Malaysian Indians (12.5%; 95% CI 17.4 to 25.9). The multivariate odds ratio of astigmatism (cylinder at least 0.75 D in either eye) in Singapore Malays compared with Malaysian Malays was 3.47 (95% CI 2.79 to 4.32). Ethnicity-specific hyperopia rates did not differ in Singapore and Malaysia. CONCLUSION: The ethnicity-specific prevalences of myopia in Singapore Malays, Chinese and Indians are higher than those in Malaysian Malays, Chinese and Indians. As Malays, Chinese and Indians in Malaysia have genetic make-up similar to that of Malays, Chinese and Indians in Singapore, environmental factors may contribute to the higher myopia rates.


Subject(s)
Refractive Errors/ethnology , Asian People/statistics & numerical data , Astigmatism/ethnology , Child , Educational Status , Female , Humans , Hyperopia/ethnology , Malaysia/epidemiology , Male , Myopia/ethnology , Prevalence , Singapore/epidemiology , White People/statistics & numerical data
20.
Br J Ophthalmol ; 90(6): 769-72, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16488932

ABSTRACT

BACKGROUND: Pterygium is a fibrovascular overgrowth from the conjunctiva onto the cornea. The pathogenesis of this common ocular surface disorder is not well understood and the only treatment is surgical removal. METHODS: DNA microarray analysis of primary pterygium tissue was carried out using uninvolved conjunctiva tissue as a comparison for gene expression levels. Real time polymerase chain reaction (PCR) was used to verify the mRNA level of expression for genes changed in pterygium. Western blot analysis and immunohistochemistry showed protein expression levels and the tissue distribution. RESULTS: Microarray analysis revealed that mRNA levels of a number of genes were changed in primary pterygium. In particular the gene for insulin-like growth factor binding protein-3, (IGFBP3), which modulates the effects of insulin-like growth factor on cells was significantly decreased. Both the message and protein expression of IGFBP3 in pterygium were decreased compared to normal, uninvolved conjunctiva. CONCLUSION: Decreased levels of IGFBP3 protein have been strongly correlated with the presence of cancer. Identification of the low level of expression of IGFBP3 in pterygium suggests that the pathway controlling cell proliferation has lost an important control mechanism, which may explain the continued growth of pterygium.


Subject(s)
Insulin-Like Growth Factor Binding Protein 3/biosynthesis , Pterygium/metabolism , Adult , Blotting, Western , Down-Regulation , Female , Humans , Insulin-Like Growth Factor Binding Protein 2/biosynthesis , Insulin-Like Growth Factor Binding Protein 2/genetics , Insulin-Like Growth Factor Binding Protein 3/genetics , Male , Middle Aged , Oligonucleotide Array Sequence Analysis/methods , Polymerase Chain Reaction/methods , RNA, Messenger/genetics , Reverse Transcriptase Polymerase Chain Reaction/methods
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