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1.
Ultrasound Q ; 31(1): 34-6, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25706362

ABSTRACT

We present the sonographic features of a second-trimester fetus diagnosed with a bradyarrhythmia at 19 weeks' gestation. The mother carried a diagnosis of Sjögren syndrome, including the presence of SSA and SSB antibodies. Ultrasound M-mode and fetal echocardiogram revealed the etiology of the bradycardia to be a complete fetal congenital heart block, likely due to transplacental passage of autoimmune anti-Ro/SSA and anti-La/SSB antibodies. Consequential to the congenital heart block, the fetus developed hydrops fetalis at 21 weeks' gestational age. We discuss the 2 major etiologies of congenital heart block and the implications in subsequent pregnancies.


Subject(s)
Antibodies, Antinuclear/immunology , Heart Block/congenital , Pregnancy Complications/immunology , Sjogren's Syndrome/diagnostic imaging , Sjogren's Syndrome/immunology , Adult , Female , Fetal Diseases/diagnostic imaging , Fetal Diseases/immunology , Heart Block/diagnostic imaging , Heart Block/immunology , Humans , Pregnancy , Pregnancy Complications/diagnostic imaging , Ultrasonography, Prenatal/methods
2.
Ann Acad Med Singap ; 43(7): 346-54, 2014 Jul.
Article in English | MEDLINE | ID: mdl-25142470

ABSTRACT

INTRODUCTION: Late preterm babies are defined as those born between 34 to 36 completed weeks. There has been a recent increased awareness that this group of babies has a higher incidence of morbidity as compared to term babies. The aim of this study was to evaluate the short-term morbidities occurring in this group of babies managed in the neonatal unit at Singapore General Hospital (SGH). MATERIALS AND METHODS: A retrospective study was done of babies managed in the neonatal unit at SGH from January 2005 to December 2008. Maternal, perinatal and neonatal data were obtained from the departmental database. The outcomes of late preterm infants were compared with term infants. RESULTS: A total of 6826 babies were admitted. Ten percent (681 out of 6826) of babies were late preterm babies, making up 63% (681 out of 1081) of all preterm babies. Late preterm babies had significantly greater need for resuscitation at birth. They also had statistically significant increased risks of developing hyaline membrane disease (2.5% vs 0.1%), transient tachypnoea of the newborn (TTN) (8.1% vs 1.7%), pneumonia (7.0% vs 2.8%), patent ductus arteriosus (PDA) (4.3% vs 1.1%), hypotension (0.7% vs 0%), apnoea (3.7% vs 0%), gastrointestinal (GI) bleeding (1.5% vs 0.3%), polycythaemia (2.2% vs 1.0%), anaemia (3.4% vs 1.2%), thrombocytopenia (3.2% vs 0.6%), hypoglycaemia (6.6% vs 1.7%), neonatal jaundice requiring phototherapy (41.1% vs 12.2%) and sepsis (1.7% vs 0.6%). CONCLUSION: Late preterm infants are indeed a vulnerable group of infants with significant morbidities that need to be addressed and treated. Despite their relatively large size and being almost term, the understanding that late preterm infants are not similar to term infants is important to both obstetricians and neonatologists.


Subject(s)
Infant, Premature, Diseases/epidemiology , Female , Gestational Age , Humans , Incidence , Infant , Infant Mortality , Infant, Newborn , Infant, Premature, Diseases/mortality , Male , Retrospective Studies , Singapore , Time Factors
4.
Radiographics ; 33(2): E61-70, 2013.
Article in English | MEDLINE | ID: mdl-23264282

ABSTRACT

Review of prior and real-time patient images is critical during an interventional radiology procedure; however, it often poses the challenge of efficiently reviewing images while maintaining a sterile field. Although interventional radiologists can "scrub out" of the procedure, use sterile console covers, or verbally relay directions to an assistant, the ability of the interventionalist to directly control the images without having to touch the console could offer potential gains in terms of sterility, procedure efficiency, and radiation reduction. The authors investigated a potential solution with a low-cost, touch-free motion-tracking device that was originally designed as a video game controller. The device tracks a person's skeletal frame and its motions, a capacity that was adapted to allow manipulation of medical images by means of hand gestures. A custom software program called the Touchless Radiology Imaging Control System translates motion information obtained with the motion-tracking device into commands to review images on a workstation. To evaluate this system, 29 radiologists at the authors' institution were asked to perform a set of standardized tasks during a routine abdominal computed tomographic study. Participants evaluated the device for its efficacy as well as its possible advantages and disadvantages. The majority (69%) of those surveyed believed that the device could be useful in an interventional radiology practice and did not foresee problems with maintaining a sterile field. This proof-of-concept prototype and study demonstrate the potential utility of the motion-tracking device for enhancing imaging-guided treatment in the interventional radiology suite while maintaining a sterile field. Supplemental material available at http://radiographics.rsna.org/lookup/suppl/doi:10.1148/rg.332125101/-/DC1.


Subject(s)
Gestures , Radiographic Image Interpretation, Computer-Assisted/instrumentation , Radiography, Interventional/instrumentation , Surgery, Computer-Assisted/instrumentation , User-Computer Interface , Video Games , Equipment Design , Equipment Failure Analysis , Humans , Touch
5.
Clin Imaging ; 35(4): 279-83, 2011.
Article in English | MEDLINE | ID: mdl-21724120

ABSTRACT

BACKGROUND: Prior studies have described a pseudocalculus appearance in the distal common bile duct as a normal variant at cholangiography. The objective of this study was to describe the occurrence of pseudotumor in the distal common bile duct at endoscopic retrograde cholangiopancreatography (ERCP). METHODS: Nine patients who underwent ERCP between May 2004 and July 2008 were identified as having a transient eccentric mural-based filling defect in the distal common bile duct. A single reader systematically reviewed all studies and recorded the imaging findings. RESULTS: The mean diameter of the filling defect was 9 mm (range, 5 to 11). Eight patients had resolution of the filling defect during the same ERCP or on a subsequent ERCP, and in two of these patients the inferior border of the filling defect was not well visualized. The other patient underwent surgical resection of a presumed tumor with no evidence of malignancy on surgical pathology. CONCLUSION: An eccentric mural-based filling defect in the distal common bile duct can be artifactual in nature and may reflect transient contraction of the sphincter of Oddi. Recognition of this pseudotumor may help avoid unnecessary surgery.


Subject(s)
Cholangiopancreatography, Endoscopic Retrograde , Common Bile Duct/diagnostic imaging , Sphincter of Oddi/pathology , Adult , Aged , Common Bile Duct/pathology , Common Bile Duct/surgery , Female , Humans , Male , Middle Aged , Retrospective Studies
6.
J Radiol Case Rep ; 5(5): 31-7, 2011.
Article in English | MEDLINE | ID: mdl-22470794

ABSTRACT

We report a case of a cystic lymphangioma arising from the lesser curvature of the stomach in a 16-year-old female who initially presented with abdominal pain, nausea, and emesis. Contrast enhanced computed tomography and magnetic resonance imaging revealed a large, thin-walled multicystic mass located anteromedial to the stomach, which was predominately supplied by the left gastric artery. Given the imaging appearance and location, a mesenteric cyst, specifically a cystic lymphangioma, was considered. Lymphangioma was the final pathological diagnosis after laparotomy with complete resection of the cystic abdominal mass.


Subject(s)
Lymphangioma, Cystic/diagnosis , Stomach Neoplasms/diagnosis , Adolescent , Diagnosis, Differential , Female , Humans , Lymphangioma, Cystic/surgery , Magnetic Resonance Imaging , Stomach/diagnostic imaging , Stomach/pathology , Stomach/surgery , Stomach Neoplasms/surgery , Tomography, X-Ray Computed
7.
J Vasc Interv Radiol ; 21(12): 1900-4, 2010 Dec.
Article in English | MEDLINE | ID: mdl-20970355

ABSTRACT

The potential role of AERO tracheobronchial covered stents in the management of recurrent postinfectious strictures of the bronchus intermedius was studied in three lung transplant recipients. Six devices were inserted. Five of the stents migrated immediately on placement. Buildup of thick mucus was observed in all stents remaining in the airway for longer than 1 week. Strictures recurred in all patients 1, 3, and 5 months after stent deployment. Attempts at stent retrieval were successful for three of five devices. The use of AERO stents may not offer a therapeutic advantage versus balloon dilation of bronchus intermedius strictures in lung transplant recipients.


Subject(s)
Airway Obstruction/therapy , Bronchial Diseases/therapy , Bronchoscopy/instrumentation , Coated Materials, Biocompatible , Lung Transplantation/adverse effects , Stents , Adult , Aged , Airway Obstruction/etiology , Alloys , Bronchial Diseases/etiology , Bronchoscopy/adverse effects , Catheterization , Constriction, Pathologic , Female , Foreign-Body Migration/etiology , Humans , Male , Middle Aged , Polyurethanes , Prosthesis Design , Recurrence , Time Factors , Treatment Outcome
8.
J Gen Intern Med ; 25(4): 321-5, 2010 Apr.
Article in English | MEDLINE | ID: mdl-20087675

ABSTRACT

BACKGROUND: Use of inferior vena cava (IVC) filters has been increasing over time. However, because of the increased risk of deep vein thrombosis with permanent filters, placement of retrievable filters has been recommended. Little is known about the factors associated with planned retrieval of IVC filters. OBJECTIVE: To describe rates and predictors of plans to retrieve IVC filters in hospitalized patients. DESIGN: We identified all IVC filter placements from 2001-2006 at an academic medical center and reviewed medical charts to obtain data about patient characteristics, filter retrieval plans, and retrieval success rates. Multivariable logistic regression was used to identify independent predictors of planned filter retrieval in patients with retrievable filters. RESULTS: Out of 240 patients who underwent placement of retrievable IVC filters, only 73 (30.4%) had documented plans for filter retrieval. Factors associated with lower rates of planned filter retrieval included a history of cancer [adjusted odds ratio (OR) and 95% confidence interval 0.2 (0.1-0.5)] and not being discharged on anticoagulants [OR 0.1 (0.1-0.3)]. In addition, 36 (21.6%) of patients without retrieval plans had no contraindications to retrieval. Of the 62 patients who underwent attempted filter retrieval, 25.8% of filters could not be successfully removed. CONCLUSIONS: Only 30.4% of patients who underwent placement of a retrievable IVC filter had documented plans for filter removal. Although most patients had justifiable reasons for filter retention, 21.6% of patients had no clear contraindications to filter removal. Efforts to improve rates of filter retrieval in appropriate patients may help reduce the long-term complications of IVC filters.


Subject(s)
Device Removal , Vena Cava Filters , Vena Cava, Inferior , Aged , Confidence Intervals , Female , Hospitalization , Humans , Logistic Models , Male , Middle Aged , Multivariate Analysis , Odds Ratio , Retrospective Studies , Risk Factors , Vena Cava Filters/classification , Venous Thrombosis/prevention & control
9.
Pacing Clin Electrophysiol ; 30(7): 891-8, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17584271

ABSTRACT

BACKGROUND: The purpose of this study is to determine whether initial vector force might best distinguish tachycardias arising from the right ventricular (RV) outflow tract (OT) versus aortic sinus cusps (ASCs). METHODS: Among 45 patients with OT tachycardia, we measured the time from the earliest QRS onset in any lead to local onset and to the first QRS peak/nadir in each surface leads during VT. We compared the earliest phase differences among patients with foci in RVOT (n = 32) and in ASCs (n = 13) (determined by ablation), using unpaired t-tests. We determined the optimum cut-points by analyzing the receiver-operator characteristics curves, and derived an algorithm to discriminate ASC from RVOT foci. RESULTS: Compared with an RVOT focus, origin in the ASC was associated with lower likelihood that the earliest lead of QRS activation was V2 (4/13 [12%] vs 29/32 [88%], P = 0.0001), later initial peak/nadir in III (110 +/- 19 vs 93 +/- 16 ms, P = 0.0026) and V2 (75 +/- 26 vs 42 +/- 19 ms, P < 0.0001). After determining the optimum cut-points for each, we found that the presence of any one of these findings discriminated well between RVOT and ASC foci (sensitivity 92%, specificity 88%, positive predictive value 75%, and negative predictive value 97%). The sensitivity and specificity using standard ECG criteria were inferior to the vector approach. CONCLUSIONS: The ECG phase differences during VT can distinguish the origin of OT-VT. Earliest onset or first peak/nadir in V2 and early initial peak/nadir in the inferior leads suggest a RVOT focus.


Subject(s)
Catheter Ablation , Electrocardiography , Tachycardia, Ventricular/physiopathology , Tachycardia, Ventricular/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Electrophysiologic Techniques, Cardiac , Female , Humans , Male , Middle Aged , Observer Variation , ROC Curve , Retrospective Studies
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