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1.
Intern Med ; 52(15): 1709-13, 2013.
Article in English | MEDLINE | ID: mdl-23903504

ABSTRACT

A 75-year-old Japanese woman with acute mitral valve prolapse and regurgitation, that developed one month previously, suffered from intractably progressive congestive heart failure (CHF). However, the emergent surgery was declined, and pharmacological treatment was discontinued due to hypotension and malignant arrhythmia. She was treated with 5-8 cmH2O of continuous positive airway pressure (CPAP) to manage CHF and Cheyne-Stokes respiration during the preoperative period of five weeks, after which plastic surgery of the mitral valve was successfully performed. CPAP can be an effective non-pharmacological treatment for CHF, unloading the left ventricle hydrostatically in order to reduce mitral regurgitation and improve oxygenation.


Subject(s)
Continuous Positive Airway Pressure , Disease Management , Heart Failure/therapy , Mitral Valve Insufficiency/therapy , Preoperative Care , Aged , Cardiac Surgical Procedures , Comorbidity , Female , Heart Failure/epidemiology , Humans , Mitral Valve Insufficiency/epidemiology , Polysomnography , Treatment Outcome
2.
Rinsho Shinkeigaku ; 52(9): 685-7, 2012.
Article in Japanese | MEDLINE | ID: mdl-22989906

ABSTRACT

We report a case of complete atrioventricular (AV) block in a 40-year-old patient with Duchenne muscular dystrophy (DMD). While he was bed-ridden and required mechanical ventilation, his cardiac involvement was mild. He had the deletion of exon 45-52 in the dystrophin gene. He underwent transient complete AV block and came to require pacemaker implantation due to recurrence of complete AV block ten days after the first attack. Electrophysiological study revealed mild prolonged AH and HV interval. Although DMD patients with AV block have been rarely reported so far, attention should be paid to AV block for patients who prolonged their lives.


Subject(s)
Atrioventricular Block/etiology , Atrioventricular Block/therapy , Muscular Dystrophy, Duchenne/complications , Pacemaker, Artificial , Adult , Atrioventricular Block/diagnosis , Dystrophin/genetics , Electrocardiography , Exons/genetics , Gene Deletion , Humans , Male , Muscular Dystrophy, Duchenne/genetics
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