ABSTRACT
Background The deep inferior epigastric perforator (DIEP) and latissimus dorsi (LD) flaps are two widely used autologous breast reconstructions. Despite studies on flap-volume changes, the time of the first measurement is not immediately after surgery. Therefore, this study aimed to investigate the change in volume over time from the immediate postoperative period using a three-dimensional (3D) scanner. Methods Patients who underwent breast reconstruction with a DIEP or LD flap between October 2019 and December 2020 at Showa University Koto Toyosu Hospital were included. The Kinect 3D scanner was used to measure the reconstructed and healthy breast volumes immediately after surgery and at 1, 3, 6, and 12 months. The control group was the healthy side, and the volumes obtained at each time point and ratios (to the immediate postoperative period) were calculated and analyzed using a linear mixed model. Results Of the 25 patients and 26 breasts examined, the postoperative increase in volume ratios was statistically significant in the DIEP flap group, except for the sixth month, but decreased significantly in the LD group. Compared with the control group, the volume ratio was significantly higher up to 3 months in the DIEP flap group and decreased significantly after 3 months in the LD flap group. Conclusions The volume of the LD flap continued to decrease immediately after surgery, whereas the volume of the DIEP flap increased by 10% up to 1M. Therefore, this increase in volume should be taken into consideration in studies where the initial measurements were not taken immediately after surgery.
ABSTRACT
An electrochemiluminescence (ECL) analytical device was developed using an electric contactless power transfer system. A mutually induced electromotive voltage was generated by wrapping an enameled wire around a commercial contactless charger. There was no electrical contact between the power supply and the electrochemical cell. For the tris(2,2'-bipyridine)ruthenium(II) (Ru(bpy)32+)/tri-n-propylamine system, a weak ECL signal was observed. When an inexpensive rectifier diode was introduced between the coil and the working electrode, the ECL intensity detection sensitivity increased by more than 100 times. The relationship between the waveform of the applied voltage and the ECL response was clarified, and the optimum conditions were determined. The intensity of the induced electromotive voltage was easily controlled by changing the number of turns in the coil. The proposed method is a safe, simple, and inexpensive technique without electrical contact.
ABSTRACT
BACKGROUND: Individuals with axillary osmidrosis suffer detrimental effects to their psychosocial functioning. In Asian nations, major operations for axillary osmidrosis include subdermal excision (open surgery) and suction-curettage (closed surgery). OBJECTIVE: The aim of this meta-analysis was to determine which of these two procedures is most favorable in terms of safety and efficacy. METHODS: According to the Preferred Reporting Items for Systematic Reviews and Metaanalyses (PRISMA) guideline, we searched electronic databases for articles published in English, Japanese, Korean, and Chinese languages. Fixed-effects model meta-analyses of odds ratios (OR) and 95% confidence intervals (CI) were conducted, and the I2 was used to assess heterogeneity. Complication rates, recurrence/ineffectiveness rates, and patient satisfaction data were extracted and compared between open and closed surgeries. RESULTS: Our search yielded 8 articles that include 1,179 patients; 560 underwent open surgery, and 619 underwent closed surgery. Our meta-analysis revealed that suction-curettage had a significantly lower risk of acute adverse events than open excision (OR, 0.15; 95% CI, 0.07~0.32), whereas open excision was significantly superior to suction-curettage for recurrence/ineffectiveness rate (OR, 2.90; 95% CI, 1.37~6.15). Patient satisfaction was equally high with both treatments (OR, 1.58; 95% CI, 0.69~3.60). CONCLUSION: Since surgical treatments for axillary osmidrosis have been performed mostly in East Asian nations, it was meaningful to review articles published in four languages. This meta-analysis revealed that closed surgery was safer but less effective than open surgery. However, both patient groups expressed high satisfaction with the outcomes. Our results may be helpful for deciding surgical treatment options.
ABSTRACT
Axillary osmidrosis is characterized by offensive odor resulting from bacterial decomposition of apocrine secretions in the axillae, and individuals with axillary osmidrosis suffer detrimental effects to their psychosocial functioning. We searched the literature in January 2019 for all English-language publications discussing axillary osmidrosis to identify previous reports, present trends, and emerging treatments. Studies were listed chronologically by the country of the first author's institution. Publications were also classified regarding the study type (literature review), pathophysiology, and treatments. We identified 133 publications on axillary osmidrosis, and of these, 120 were from East-Asian countries. Before 1990, there were only 9 publications, but after 2000, publications increased in number. One hundred of 133 reports discussed treatment, namely, 39 reports on suction curettage, 28 reports on open surgery, and 8 reports on subdermal laser. Other studies focused on the pathophysiology of axillary osmidrosis. This literature review revealed unique trends in the identified studies. Because control of axillary odor is a universal subject, the etiology and pathophysiology of axillary osmidrosis have been studied throughout the world and are clearly described. However, almost all studies of surgical treatments have been performed in East-Asian countries. After the year 2000, various surgical and nonsurgical treatments, namely, laser therapy and suction curettage, have been attempted. Emerging treatments for axillary osmidrosis include ethanol injections, microwave therapy, and microneedle radiofrequency technologies; however, further studies of these treatments are needed.
Subject(s)
Hyperhidrosis , Sweat Gland Diseases , Apocrine Glands , Axilla , Asia, Eastern , Humans , Hyperhidrosis/therapy , Odorants , Sweat Gland Diseases/diagnosis , Sweat Gland Diseases/therapyABSTRACT
The molecular tiling method is proposed as a novel methodology to provide an artificial molecular arrangement at the air-water interface by assembling rigid amphiphilic units like tile pieces. In this study, the mixed monolayers of cyclic phenylazomethine (CPA) as a rigid triangle basement and dihexadecyl phosphate (DHP) as a monolayer-forming component were investigated by pi-A isotherm measurement and Fourier transform infrared (FTIR) spectroscopy in the reflection-absorption mode in order to provide basic knowledge of molecular tiling design. Although the CPA molecules alone cannot form a stable monolayer on water, monolayers of DHP/CPA mixtures showed two-step condensed phases that reflect two kinds of assembling modes of alkyl chains of these components. FTIR spectra of the transferred monolayers indicated specific interaction of the amine part in CPA and the phosphate moiety of DHP. pi-A isotherms of the systematic change in the mixing ratio revealed the binding stoichiometry between DHP and the CPA to be 3:1. Interaction of DHP molecules to three basic sites of CPA and matching in cross-sectional area between three DHP molecules and CPA core would result in the stable formation of the 3:1 complex.
