ABSTRACT
The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block.
Subject(s)
Arrhythmias, Cardiac/chemically induced , Cocaine/adverse effects , Electrocardiography/drug effects , Hospitalization , Myocardial Infarction/chemically induced , Substance-Related Disorders/rehabilitation , Adult , Bundle-Branch Block/chemically induced , Coronary Disease/chemically induced , Female , Humans , Male , Retrospective StudiesABSTRACT
We examined the records of 53 patients with a diagnosis of bipolar affective disorder, manic. Thirteen patients were refractory to lithium carbonate treatment. Clinical variables hypothesized to have value in predicting response including the presence of elation, grandiosity, paranoia, irritability, delusions and hallucinations did not predict treatment response.
Subject(s)
Bipolar Disorder/drug therapy , Lithium/therapeutic use , Activities of Daily Living/psychology , Adult , Bipolar Disorder/blood , Bipolar Disorder/psychology , Female , Hospitalization , Humans , Lithium/pharmacokinetics , Lithium Carbonate , Male , Psychiatric Status Rating Scales , Retrospective Studies , Social AdjustmentSubject(s)
Cocaine , Mental Disorders/complications , Substance-Related Disorders/complications , Adult , Alcoholism/complications , Female , Humans , Inpatients , MaleABSTRACT
The incidence and type of drug abuse for 50 male schizophrenic patients and 60 male and female bipolar, manic patients were determined. Fifty percent of schizophrenic patients and 25% of bipolar patients abused one or more drugs. Alcohol, cannabis, and cocaine accounted for 82% of the drug abuse.
