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1.
BMJ Case Rep ; 17(3)2024 Mar 27.
Article in English | MEDLINE | ID: mdl-38538095

ABSTRACT

Infectious aortitis is a rare disease process which can be of fungal, viral or bacterial aetiology. This disease process is often incidentally found during concomitant infectious processes, likely due to haematogenous spread. Common sources are from cardiac, genitourinary and gastroenterologic sources. CT imaging of the aorta is essential in identifying physiological changes-wall thickness changes, ectasia and stenosis. We present a case of a female in her early 60s with a medical history of cardiomyopathy with heart failure and reduced ejection fraction, who was initially admitted for acute cholecystitis complicated by the development of gallstone pancreatitis. Imaging evaluation incidentally noted findings consistent with aortitis with a penetrating ulcer, and blood cultures were positive for Staphylococcus aureus bacteraemia, confirming her diagnosis of infectious aortitis. She was started on intravenous antibiotics, required preoperative nutritional optimisation, and subsequently underwent an open aortic resection and aortoiliac reconstruction with rifampin-soaked Dacron graft.


Subject(s)
Aortitis , Bacteremia , Soft Tissue Infections , Staphylococcal Infections , United States , Humans , Female , Aortitis/diagnosis , Aortitis/therapy , Aortitis/complications , Bacteremia/complications , Hospitals, Military , Staphylococcal Infections/complications , Staphylococcus aureus , Soft Tissue Infections/complications
2.
J Radiol Nurs ; 40(3): 239-240, 2021 Sep.
Article in English | MEDLINE | ID: mdl-34149327

ABSTRACT

A 19-year-old male with a history of chronic tonsillitis presented to the emergency department for a 3-day history of progressively worsening odynophagia and blood-tinged saliva for greater than 48 hr, and found to have "kissing tonsils" on examination with bilateral exudates and venous oozing. Spontaneous tonsillar hemorrhage, also described as hemorrhagic tonsillitis, is a rare complication of acute or chronic tonsillitis with a reported incidence of less than 1.1% of all infectious tonsillitis cases worldwide. Emergent airway assessment is critical in patients presenting with potential airway obstruction. In patients presenting with spontaneous tonsillar hemorrhage, hemostasis should also be achieved, whether topically, or through emergent tonsillectomy should the patient's clinical status warrant it.

3.
J Surg Res ; 263: 186-192, 2021 07.
Article in English | MEDLINE | ID: mdl-33677146

ABSTRACT

BACKGROUND: Patients who take aspirin and sustain traumatic intracranial hemorrhage (tICH) are often transfused platelets in an effort to prevent bleeding progression. The efficacy of platelet transfusion is questionable, however, and some medical societies recommend that platelet reactivity testing (PRT) should guide transfusion decisions. The study hypothesis was that utilization of PRT to guide platelet transfusion for tICH patients suspected of taking aspirin would safely identify patients who did not require platelet transfusion. METHODS: This was a retrospective study of patients with blunt tICH who received PRT for known or suspected aspirin use between June 2014 and December 2017 at a level I trauma center. Chart abstraction was conducted to determine home aspirin status, and PRT values were used to classify patients as therapeutic or nontherapeutic on aspirin. Differences were assessed with Kruskal-Wallis and chi-square tests. RESULTS: 157 patients met study inclusion criteria, and 118 (75%) patients had documented prior aspirin use. PRT results were available approximately 1.7 h (IQR: 0.9, 3.2) after arrival. Upon initial PRT, 70% of patients were considered inhibited and 88% of those patients had aspirin documented as a home medication. Conversely, 18% of patients with home aspirin use had normal platelet reactivity. Clinically significant worsening of the tICH did not significantly differ when comparing those who received platelet transfusion with those who did not (8% versus 7%, P = 0.87). CONCLUSIONS: Platelet reactivity testing can detect platelet inhibition related to aspirin and should guide transfusion decisions for head injured patients in the initial hours after trauma.


Subject(s)
Aspirin/adverse effects , Intracranial Hemorrhage, Traumatic/therapy , Platelet Aggregation Inhibitors/adverse effects , Platelet Transfusion/standards , Aged , Aged, 80 and over , Blood Coagulation Tests , Disease Progression , Female , Humans , Intracranial Hemorrhage, Traumatic/blood , Intracranial Hemorrhage, Traumatic/diagnosis , Male , Middle Aged , Platelet Aggregation , Practice Guidelines as Topic , Retrospective Studies
4.
J Clin Sleep Med ; 16(1): 91-96, 2020 01 15.
Article in English | MEDLINE | ID: mdl-31957659

ABSTRACT

STUDY OBJECTIVES: Sleep-disordered breathing (SDB) is a common disorder that causes people to stop breathing in their sleep, and obstructive sleep apnea (OSA) is the most common form of SDB in the general population. Because OSA is often undiagnosed and undermanaged, it has been associated with adverse events and morbidity in hospitalized patients. The purpose of the study was to evaluate prevalence of OSA risk in a population of patients who survived a medical emergency team (MET) activation during hospitalization. METHODS: This prospective study was conducted at a hospital in the Midwest in 2014. Patients who survived a MET activation and consented to participate were administered the STOP-Bang questionnaire and asked other health and lifestyle questions. Review of the medical record was conducted to ascertain patient characteristics, comorbidities, and medications. Differences were assessed using Kruskal-Wallis one-way analysis of variance and the chi-square test. RESULTS: Of 148 study patients, median age was 68 years (interquartile range: 55-78) and 15% were morbidly obese (body mass index ≥ 40 kg/m²). Fifty percent of patients (n = 74) were found to be at high risk for OSA, yet only 38% (n = 28) of those patients received a previous diagnosis of OSA. Variables available in the medical record were highly correlated with the overall STOP-Bang score (r =. 75, P < .001). CONCLUSIONS: Half of patients who survived a MET activation during hospitalization screened at high risk for OSA. Standardized screening for risk of sleep apnea, as well as a truncated risk score generated by variables in the medical record, could guide clinical decision making in this at-risk population.


Subject(s)
Obesity, Morbid , Sleep Apnea, Obstructive , Aged , Humans , Polysomnography , Prevalence , Prospective Studies , Sleep Apnea, Obstructive/epidemiology , Surveys and Questionnaires
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