Free choice feeding of whole grains in meat-type pigeons: 1. effect on performance, carcass traits and organ development.

The effects of 5 different feeding systems on the performance, carcass traits and organ development were studied in pigeon squabs. The 5 treatments were (1) whole grains of maize, pea and wheat plus concentrate feed; (2)whole grains of maize and wheat plus concentrate feed (CWC); (3) whole grains of maize and pea plus concentrate feed; (4)whole grain of maize plus concentrate feed (CC); and (5) compound feed (CF). Feed intake of parent pigeons increased significantly from 0 to 21 d and it was higher in the CF treatment. Body weight of squabs in the CWC treatment was the highest among the 5 treatments in 4 weeks. Body weight losses of parental pigeons during the rearing period were not significantly different among the 5 treatments. Protein intake in CC and CWC treatments was lower than that of the other three treatments. The CWC treatment had the highest daily weight gain and the lowest feed conversion ratio. Treatments were statistically similar in the relative weight of carcass, breast and thigh. CF had the lower relative weight of abdominal fat. Relative weight of gizzard in the CF treatment was significantly lower than that of CWC. It was concluded that the application of free choice feeding of whole grains of maize and wheat plus concentrate feed increased the body weight of 28-d-old pigeon squabs and decreased the feed conversion rate of parent pigeons. This feeding strategy could be commercially interesting in meat-type pigeon production.

A proteomics analysis reveals that A2M might be regulated by STAT3 in persistent allergic rhinitis.

BACKGROUND: Proteomics tools can be used to identify the differentially expressed proteins related to allergic rhinitis (AR). However, the large numbers of proteins related to AR have not yet been explored using an advanced quantitative proteomics approach, known as isobaric tags for relative and absolute quantitation (iTRAQ). OBJECTIVES: To identify differentially expressed proteins in persistent AR patients and to explore the regulatory signalling pathways involving the identified proteins. METHODS: Forty-five persistent AR patients and 20 healthy controls were recruited for this study. iTRAQ was used to identify the proteins that were differentially expressed between these two groups, and a bioinformatics analysis was then conducted to identify the signalling pathways associated with the identified proteins. Immunofluorescence labelling was performed to detect alpha-2-macroglobulin (A2M), STAT3, p-STAT3 and IL17 in the nasal mucosa. RESULTS: A total of 133 differentially expressed proteins were identified. We then determined the top 10 regulatory pathways associated with these proteins and found that the blood coagulation pathway had the most significant association. A2M, a protein involved in the blood coagulation pathway, was found to be differentially expressed in the serum of AR patients. The bioinformatics analysis indicated that STAT3 is an upstream transcription factor that might regulate A2M expression. An immunofluorescence study further confirmed that STAT3 and A2M are co-localized in nasal mucosa cells. Additionally, A2M, STAT3, p-STAT3, and IL17 are elevated in AR patients. The expressional level of A2M is positively related to IL17 and the symptom of the congestion in AR subjects. CONCLUSIONS: The blood coagulation pathway may be a key regulatory network pathway contributing to the allergic inflammatory response in AR patients. A2M, which is regulated by STAT3, may be an important protein in the pathogenesis of allergic rhinitis in AR patients.

Metabolizable energy and fiber digestibility of uncommon feedstuffs for geese.

This experiment was conducted to study the digestibility of uncommon feedstuffs for geese. Thirty Taihu ganders were selected and divided into 5 groups (n = 6), and one group was allocated as the control. Taihu ganders in the 4 treated groups were force-fed with a weight of different uncommon feedstuffs after 24 h of fasting, and the control group was kept in fasting with no force feeding. All excretion of each gander was collected on a plate for 24 h after force feeding. There was a 12-d recovery period between treatments. In this study, we measured the ME and analyzed neutral detergent fiber, acid detergent fiber, and hemicellulose of brewers grains, distillers grains, empty-grain rice, ryegrass powder, rice husk, corn stalk, rice straw, wheat straw, wheat husk, mushroom bran, and peanut vine. The TME values were 9.29, 8.67, 8.97, 5.89, 3.85, 3.10, 3.32, 3.02, 5.29, 2.48, and 3.15 MJ/kg, respectively. The digestibility of neutral detergent fiber for the feedstuffs ranged from 6.14 to 45.0%, the digestibility of acid detergent fiber ranged from 4.52 to 32.6%, and the digestibility of hemicellulose ranged from 18.5 to 61.6%. The best TME quadratic prediction equation was TME = 12.2 - 0.232CF, where CF is crude fiber. These results suggest that geese were able to use uncommon feedstuffs with high digestibility, and there was a significant negative correlation between energy digestibility and CF content. The ME values tested in this experiment can provide a foundation for preparation and adjustment of feed formulation for reasonable use of uncommon feedstuffs for geese.

The influence of different movements on ambulatory blood pressure in hypertensive subacute stroke patients.

OBJECTIVE: This study evaluated variation in blood pressure (BP) in hypertensive subacute stroke patients performing eight different types of active movement, and variations in BP over time. METHODS: The study included 35 subacute stroke patients (60 - 74 years old) and 15 age-matched healthy volunteers. Ambulatory systolic and diastolic BP was measured over 4 consecutive days, before and during active movement. RESULTS: The greatest effect of the different active movements in stroke patients was on mean systolic BP variability (BPV). There was a significant difference in systolic and diastolic BPV between stroke patients at different time-points and compared with healthy volunteers. Systolic BPV during shifting from the ward to the rehabilitation centre was significantly higher than for all other active movements. Mean systolic BPVs during the sessions on the first and second days were significantly higher than for the sessions on the third and fourth days in stroke patients and compared with healthy volunteers. CONCLUSIONS: Systolic BP was found to be increased in hypertensive subacute stroke patients during their first and/or second attempts at performing active movements. Therapists should consider the BP of hypertensive subacute stroke patients during these first two attempts, especially for activities involving the patient moving from the ward to the rehabilitation centre.

[Cytosol estrogen and progesterone receptors in female genital system malignant tumors].

Specimens from 344 cases of endometrial carcinoma, 289 cases of ovarian carcinoma, 177 cases of cervical carcinoma, 10 vulva and 4 fallopian tube carcinoma were assayed for cytosol estrogen and progesterone receptor (ER, PR) contents with dextran-coated charcoal (DCC) method. Positive rates of ER and PR in these malignant tumors in relation to menstrual cycle, histological differentiation, clinical stage and prognosis of disease were studied. The results suggested that the contents of ER and PR may play a role in building endocrine therapy and prognosis in the postoperative period. Further study on vulvar and fallopian tube carcinomas should be undertaken.