Changes in diet quality across life transitions from adolescence to early adulthood: a latent growth analysis.

Background: Adolescence to early adulthood is a period of multiple education-, employment- and family-related life transitions. Changing resources and food environments within the context of these transitions could contribute to significant changes in diet, which persist into later adulthood. This study investigated diet quality trajectories from age 15 to 31 years and changes in diet quality associated with life transitions, by sex. Methods: Data from the Project EAT (Eating and Activity in Teens and Young Adults) study were used to examine diet quality among a longitudinal cohort (n=2,524) across four waves (mean ages of 15, 19, 25 and 31 years). Diet quality was evaluated using the DASH (Dietary Approaches to Stop Hypertension) index. Life transitions were assessed by changes in life circumstances between pairs of waves, including leaving the parental home, leaving full-time education, beginning full-time employment, cohabitating with a partner, and becoming a parent. Average within-person changes in DASH scores were analysed by sex-specific latent growth models, incorporating underlying growth trajectories, five life transitions and baseline socio-demographic characteristics. Results: Both sexes followed a quadratic trajectory of DASH scores, showing decreases in diet quality from waves 1 to 2 followed by increases until wave 4. Compared to females, males had worse diet quality at wave 1, and this sex difference widened at wave 4. Leaving the parental home between waves 1 and 2 was associated with transient decreases in diet quality at wave 2 only for males. For females, cohabitating with a partner and becoming a parent between waves 3 and 4 were respectively related to decreases and increases in diet quality at wave 4. Leaving full-time education and starting full-time employment respectively had long-term negative and positive associations with diet quality for both sexes. Conclusions: Diet quality remained suboptimal throughout adolescence but to some extent improved across early adulthood. A sex-sensitive approach in public health policy is welcome for addressing sex differences in diet quality and dietary changes associated with family-related life transitions. Targeted dietary interventions are beneficial for young people who leave their parental home early or who do not enter into a structured school or workplace environment.

Fabrication of Porous Crystalline PLGA-PEG Induced by Swelling during the Recrystallization Annealing Process.

Poly(lactide-co-glycolide) (PLGA) has been widely used as a scaffold material for tissue engineering owing to its biocompatibility, biodegradability, and biosafety. However, lactic acid (LA) produced during PLGA degradation is prone to inflammation, which is a shortcoming that must be avoided. To this end, crystalline PLGA-PEG was synthesized here for the first time. To make the crystalline PLGA-PEG more suitable for tissue engineering, porous crystalline PLGA-PEG was prepared via the swelling behavior during recrystallization annealing. The structure and properties of the porous crystalline PLGA-PEG were confirmed by SEM, POM, and XRD. Furthermore, the swelling behavior of different PEG molecular weights was studied, and the cell viability test and alkaline phosphatase activity test showed that PLGA-PEG has good biocompatibility. Such a porous crystalline PLGA-PEG will make PLGA have a broader application prospect in bone repair.

Mobility-based environmental justice: Understanding housing disparity in real-time exposure to air pollution and momentary psychological stress in Beijing, China.

Environmental justice is a crucial environmental and social problem. Previous research in the cities of developed countries has found that ethnic minorities and low-income people were disproportionately exposed to the residential environment with more serious environmental risks. This study proposed a transition from the residence-based perspective to a mobility-based and context-aware approach to reinterpret environmental justice with a focus on the air pollution issue in urban China. A novel research protocol combining geographic ecological momentary assessment and portable air pollutant sensors was developed to collect and analyze real-time data of air pollution exposure and psychological stress for residents living in the same residential neighborhood of Beijing, China. The results show that residents of different types of housing were exposed to varying PM2.5 concentrations although they experienced similar levels of air pollution in their residential neighborhoods. Residents of public low-rent housing were the disadvantaged group because of their limited mobility, exposure to serious air pollution at home, and insensitive stress responses to air pollution. These findings not only uncover the mobility-based environmental justice issue in the context of government-led and egalitarianism-pursuing urban China, but also provide references for the residential mix policy on how to narrow the disparity in environmental pollution exposure from the perspective of human mobility.

Associations of co-exposures to air pollution and noise with psychological stress in space and time: A case study in Beijing, China.

Air pollution and noise are both ubiquitous environmental stressors that pose great threats to public health. Emerging evidence has noticed the combined health risks caused by the coexistence of traffic-related air pollutants and noise in the residential context. However, less is known about how mobile individuals are simultaneously exposed to multiple sources of air pollution and noise, and thus respond with more acute psychological responses beyond the residence. This study examines the co-exposures to fine particles (PM2.5) and noise across spatiotemporal contexts where the concurrent exposures are jointly associated with momentary psychological stress. An innovative research protocol, including GPS-equipped activity-travel diaries, air pollutant and noise sensors, and ecological momentary assessment, was adopted to collect real-time data from a sample of residents in Beijing, China. The results showed a minor correlation between PM2.5 and noise exposures after accounting for individual mobility and the spatiotemporal dynamics of these two environmental pollutants. Further, exposure to PM2.5 was more associated with momentary psychological stress given the insignificant independent effect and the weak moderating effect of noise exposure. Three specific spatiotemporal contexts involving the health risks of co-exposures were delineated, including morning rush hours and traveling by public transits with intensified stress risks caused by combined exposures to air pollution and noise, workplaces with counteracting stress effect of both exposures, and evening time at home with stress-induced air pollution and stress-relieving social noise. In conclusion, the mobility-based and context-aware analysis provides a more nuanced understanding of the associations of co-exposures to environmental pollution and synchronous psychological stress in space and time.

Understanding the relationships among individual-based momentary measured noise, perceived noise, and psychological stress: A geographic ecological momentary assessment (GEMA) approach.

This study aims to understand how the relationship between individual-based noise exposure and psychological stress is influenced by perceived noise and context. Using geographic ecological momentary assessment, along with activity-travel diaries, GPS tracking, and portable noise sensors, this study collected real-time data of individuals' daily movement, noise exposure, and self-reported noise perception and psychological stress. Structural equation modeling was used to examine the direct and indirect pathways among context, momentary measured noise, perceived noise, and psychological stress. The study finds that momentary measured noise influences psychological stress through the mediating effect of perceived noise. Further, different activity and travel, social, and temporal contexts significantly influence people's momentary measured noise, perceived noise, and psychological stress. These findings advance our understanding of specific contexts, individual-based objectively measured and subjectively perceived environmental exposures, and their effects on psychological health at a high spatiotemporal resolution.

The Anatomy of Health-Supportive Neighborhoods: A Multilevel Analysis of Built Environment, Perceived Disorder, Social Interaction and Mental Health in Beijing.

Mental health is an exceedingly prevalent concern for the urban population. Mounting evidence has confirmed the plausibility of high incidences of mental disorders in socioeconomically disadvantaged neighborhoods. However, the association between the neighborhood built environment and individual mental health is understudied and far from conclusive, especially in developing countries such as China. The underlying mechanism requires in-depth analysis combining potential intermediates such as perceived environmental disorder and supportive social relationships. Using a health survey conducted in Beijing in 2017, this study investigates for the first time a socio-environmental pathway through which perceived disorder and social interaction account for the relationship between the built environment and mental health under the very notion of the neighborhood effect. The results from multilevel structural equation models indicate that individual mental health is influenced by the neighborhood-scale built environment through three pathways, independent of neighborhood socioeconomic disadvantages: (1) proximity to parks is the sole indicator directly linked to mental health; (2) population density, road connectivity and proximity to parks are indirectly associated with mental health through interactions with neighbors; and (3) population density, road connectivity and facility diversity are partially associated with perceived neighborhood disorder, which is indirectly correlated with mental health through interactions with neighbors. This study is a preliminary attempt to disentangle the complex relationships among the neighborhood environment, social interaction and mental health in the context of developing megacities. The relevant findings provide an important reference for urban planners and administrators regarding how to build health-supportive neighborhoods and healthy cities.

Structure modulation of manganese coordination polymers consisting of 1,4-naphthalene dicarboxylate and 1,10-phenanthroline.

Three new manganese coordination polymers, {[Mn2(1,4-NDC)2(phen)2](H2O)}n (1), [Mn2(1,4-NDC)2(phen)(H2O)]n (2) and {[Mn4(1,4-NDC)4(phen)4](DMF)2}n (3) (1,4-H2NDC = 1,4-naphthalene dicarboxylic acid; phen = 1,10-phenanthroline; DMF = N,N-dimethylformamide), have been synthesized solvo/hydrothermally. 1,4-NDC(2-) ligands adopt different coordination modes under different solvents and concentrations which promotes different crystal structure formation. X-ray crystal structural data reveal that compounds 1, 2 and 3 crystallize in monoclinic space groups C2/c, P21/c and C2/c, respectively. Compound 1 has Mn2 dimers connected by 1,4-NDC(2-) linkers, packing into a 2D structure in a grid pattern. Compound 2 has a three-dimensional (3D) structure which is constructed by Mn2 dimers and 1,4-NDC(2-) linkers. Each MnO4N2 node of compound 3 is linked to another by 1,4-NDC(2-) ligands to form a two-dimensional (2D) structure. Variable-temperature magnetic susceptibilities of compounds 1-3 exhibit overall weak antiferromagnetic coupling between the adjacent Mn(II) ions.