ABSTRACT
Three cases of granulomatous orchitis are presented; they were observed during a period of 30 years among 44 testicular tumors. The testis was always uniformly enlarged. The aspect of granulomatous inflammation predominated with nodules or large zones formed from histiocytes, epithelioid cells and more rarely giant, multinucleated cells, and surrounded or intersperced by lymphocytes, plasma cells, fibrocytes and collagen fibers. The epithelial testis component was more or less damaged. The differential diagnosis has to be performed with tuberculosis, sarcoidosis, syphilis, malignant lymphoma and malacoplasia; the clinical data are very important for diagnosis. The traumatic, ischemic, infectious, fungal and autoimmune nature of these lesions is discussed.
Subject(s)
Orchitis/pathology , Aged , Diagnosis, Differential , Epididymitis/etiology , Granuloma/etiology , Humans , Male , Middle Aged , Orchitis/complications , Testicular Neoplasms/diagnosisSubject(s)
Malacoplakia/pathology , Prostatic Diseases/pathology , Aged , Humans , Male , Prostate/pathologySubject(s)
Sarcoma, Synovial/diagnosis , Adult , Diagnosis, Differential , Female , Humans , Joint Diseases/diagnosis , Synovitis/diagnosisSubject(s)
Granulosa Cell Tumor/diagnosis , Ovarian Neoplasms/diagnosis , Adolescent , Adult , Child , Diagnosis, Differential , Female , Histological Techniques , HumansSubject(s)
Ovary/pathology , Uterine Cervical Neoplasms/pathology , Uterine Neoplasms/pathology , Aged , Female , Humans , Menopause , Middle AgedABSTRACT
The authors report on three phyllod Tumours of the breast, two benign and one malignant conditions. They insist on the histological aspect of the tumour, underlining that in the benign forme both, epithelial and mesenchymal components does not present atypies, while in the malignant form only the mesenchymal component gets malign sarcomatous character. The microscopic aspect of the tumour and its clinical evolution are suspicious. The diagnosis can be specified only by the histopathological examination. The origin of the phyllod tumour is not clear and the authors discuss the possibility of its development upon a preexistent tumour, specifically on a fibroadenoma of the breast. The treatment is guided by the microscopic appearances. Generally they perform the ablation of the tumour when its dimensions are not greater then 10 cm. and the simple mastectomy when its diameter exceeds this dimension.