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1.
Ann Thorac Surg ; 100(5): e103-5, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26522573

ABSTRACT

We report a case of intercostal muscle flap used in tracheobronchial reconstruction for extensive necrosis after burn lesions of the posterior wall. A 32-year-old man attempted suicide by ingestion of caustic material. He underwent emergency total esogastrectomy, tracheostomy, and feeding jejunostomy. Ten days later, endoscopy showed complete destruction of the membranous trachea, extending from the tracheostomy to the carina. Reconstruction was conducted with the patient under venovenous extracorporeal membrane oxygenation by use of a pedicled intercostal muscle flap. The patient was weaned from respiratory support on the 14th postoperative day. Examination of a biopsy specimen from the flap 7 months after tracheoplasty showed ciliated neoepithelium.


Subject(s)
Burns, Chemical/complications , Intercostal Muscles/transplantation , Plastic Surgery Procedures/methods , Surgical Flaps , Trachea/surgery , Tracheal Stenosis/surgery , Adult , Burns, Chemical/pathology , Burns, Chemical/surgery , Humans , Male , Necrosis/etiology , Necrosis/pathology , Necrosis/surgery , Suicide, Attempted , Trachea/injuries , Tracheal Stenosis/chemically induced
3.
Chin Clin Oncol ; 4(4): 40, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26730752

ABSTRACT

BACKGROUND: Whether prophylactic tracheotomy can shorten the duration of mechanical ventilation (MV) in high risk patients eligible for lung cancer resection. The objective was to compare duration of MV and outcome in 39 patients randomly assigned to prophylactic tracheotomy or control. METHODS: Prospective randomized controlled, single-center trial (ClinicalTrials.gov Identifier: NCT01053624). The primary outcome measure was the cumulative number of MV days after operation until discharge. The secondary outcome measures were the 60 days mortality rate, the ICU and the hospital length of stay, the incidence of postoperative respiratory, cardiac and general complications, the reventilation rate, the need of noninvasive ventilation (NIV), the need of a tracheotomy in control group and the tracheal complications. RESULTS: The duration of MV was not significantly different between the tracheotomy group (3.5±6 days) and the control group (4.7±9.3 days) (P=0.54). Among patients needing prolonged MV >4 days, tracheotomy patients had a shortened duration of MV than control patients (respectively 11.4±7.1 and 20.4±9.6 days, P=0.04). The rate of respiratory complications were significantly lower in the tracheotomy group than in the control group (28% vs. 51%, P=0.03). Six patients (15%) needed a postoperative tracheotomy in the control group because of a prolonged MV >7 days. Tracheotomy was associated with a reduced need of NIV (P=0.04). There was no difference in 60-day mortality rate, cardiac complications, intensive care unit and hospital length of stay. No death was related with the tracheotomy. CONCLUSIONS: Prophylactic tracheotomy in patients with ppo FEV1 <50% who underwent thoracotomy for lung cancer resection provided benefits in terms of duration of prolonged MV and respiratory complications but was not associated with a decreased mortality rate, ICU and hospital length of stay and non-respiratory complications.


Subject(s)
Lung Neoplasms/surgery , Lung/surgery , Pneumonectomy , Respiration, Artificial , Respiratory Tract Diseases/therapy , Thoracotomy , Tracheotomy , Aged , Female , Forced Expiratory Volume , France , Humans , Length of Stay , Lung/pathology , Lung/physiopathology , Lung Neoplasms/mortality , Lung Neoplasms/pathology , Lung Neoplasms/physiopathology , Male , Middle Aged , Pneumonectomy/adverse effects , Pneumonectomy/mortality , Prospective Studies , Recovery of Function , Respiration, Artificial/adverse effects , Respiratory Tract Diseases/etiology , Respiratory Tract Diseases/mortality , Respiratory Tract Diseases/physiopathology , Risk Factors , Thoracotomy/adverse effects , Thoracotomy/mortality , Time Factors , Tracheotomy/adverse effects , Tracheotomy/mortality , Treatment Outcome
4.
Chin Clin Oncol ; 4(4): 43, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26730755

ABSTRACT

Only few reports of surgical approach to T4 lung carcinoma invading the heart have been reported in the medical literature. It is also controversial if such cancer should be treated by surgery. The aim of this review is to assess the current risk/benefit ratio of the surgical management of non-small cell lung cancer (NSCLC) invading the left atrium, especially in the light of a multidisciplinary approach. We also expose our surgical experience and the procedure we have developed in order to increase our rate of complete resection as this criterion appears to be mandatory as well as patients' nodal status in order to increase life expectancy.


Subject(s)
Carcinoma, Non-Small-Cell Lung/surgery , Cardiac Surgical Procedures , Heart Atria/surgery , Lung Neoplasms/surgery , Pneumonectomy , Carcinoma, Non-Small-Cell Lung/mortality , Carcinoma, Non-Small-Cell Lung/pathology , Cardiac Surgical Procedures/adverse effects , Cardiac Surgical Procedures/mortality , Heart Atria/pathology , Humans , Lung Neoplasms/mortality , Lung Neoplasms/pathology , Neoplasm Invasiveness , Patient Selection , Pneumonectomy/adverse effects , Pneumonectomy/mortality , Risk Factors , Treatment Outcome
5.
J Vasc Surg ; 62(4): 1068-70, 2015 Oct.
Article in English | MEDLINE | ID: mdl-24745943

ABSTRACT

Thoracic duct (TD) cyst is an uncommon abnormality that can be manifested as a cervical swelling. Pathogenesis includes congenital or degenerative weakness of the wall of the TD and obstruction of the lymphoid flow. Diagnosis is crucial to eliminate malignant disease or vein thrombosis and can be established by imaging and needle aspiration. We report a case of recurrent cervical swelling with spontaneous chylothorax and chyloperitoneum. A TD cyst with a terminal obstruction of the TD was diagnosed on lymphangiography. Treatment by microsurgical lymphovenous anastomosis was successful, and the patient was free of symptom 3 years later.


Subject(s)
Lymphocele/surgery , Thoracic Duct , Adult , Chylothorax/etiology , Chylous Ascites/etiology , Female , Humans , Jugular Veins/surgery , Lymphocele/complications , Lymphocele/diagnosis , Lymphography , Neck
6.
Ann Thorac Surg ; 97(5): 1708-13, 2014 May.
Article in English | MEDLINE | ID: mdl-24625436

ABSTRACT

BACKGROUND: Extended resection for lung cancer may improve survival of selected patients. Left-atrial resection is infrequently performed and surgical techniques are rarely reported; thus, oncologic results and survival rates remain uncertain. Our study describes surgical techniques, postoperative outcomes, and oncologic results of patients who received a combined multimodality treatment. METHODS: Between October 2004 and March 2012 in our institution, 19 patients underwent extended lung resection involving the left atrium without cardiopulmonary bypass. We reviewed perioperative treatments, surgical procedures, and postoperative morbidity, mortality, and long-term survival rates. RESULTS: Sixteen patients (68.4%) underwent neoadjuvant treatment including chemotherapy or radiotherapy. Eighteen pneumonectomies (94.7%) were performed, of which 12 (63.1%) were right sided. Dissection of the interatrial septum was complete in 4 patients (33.3%). Complete resection was achieved in 17 patients (89.4%) and 2 other patients (10.5%) were considered R1. The T-status was pT4 in all patients. Overall postoperative morbidity was 52.6%. The 30-day mortality rate was 10.5% and the 90-day mortality rate was 15.7%. Fifteen patients (93.7%) underwent adjuvant treatment. The mean follow-up time was 32.5 months. The 5-year probability of survival was 43.7%. Three patients (15.7%) were alive at greater than 6 years postsurgery. CONCLUSIONS: Extended lung surgery with partial resection of the left atrium is a feasible procedure with acceptable morbidity. An interatrial septum dissection, by increasing the length of the atrial cuff, allows complete resection. Long-term survival can be achieved in highly selected patients who have undergone multimodal therapy.


Subject(s)
Carcinoma, Non-Small-Cell Lung/therapy , Heart Atria/surgery , Lung Neoplasms/therapy , Neoadjuvant Therapy , Pneumonectomy/methods , Adult , Aged , Carcinoma, Non-Small-Cell Lung/mortality , Carcinoma, Non-Small-Cell Lung/pathology , Cardiac Surgical Procedures/methods , Cardiopulmonary Bypass , Chemoradiotherapy/methods , Cohort Studies , Databases, Factual , Disease-Free Survival , Female , Heart Atria/pathology , Humans , Kaplan-Meier Estimate , Lung Neoplasms/mortality , Lung Neoplasms/pathology , Male , Middle Aged , Neoplasm Invasiveness/pathology , Neoplasm Staging , Prognosis , Proportional Hazards Models , Retrospective Studies , Survival Analysis
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