ABSTRACT
A primary tumor composed of mature adipose tissue and smooth muscle occurring in the anterior abdominal wall of a 46 yr old Filipino woman is described. The tumor was not attached to the uterus, but had an appearance similar to a uterine lipoleiomyoma. It appeared as a soft, rubbery, encapsulated 11 cm ovoid mass with a uniform, white cut surface. Histologically, there were long intersecting bundles of bland smooth muscle mixed with nests of mature fat cells. The presence of differentiated smooth muscle was confirmed by fuchsinophilia, desmin positivity and electron microscopy. The patient also had 6 intramural leiomyomas, an area of adenomyosis, a subcutaneous lipoma of the subscapular region and chronic schistosomiasis of the appendix and left adnexa.
Subject(s)
Leiomyoma/pathology , Lipoma/pathology , Soft Tissue Neoplasms/pathology , Adipose Tissue/chemistry , Adipose Tissue/pathology , Adipose Tissue/ultrastructure , Desmin/analysis , Female , Humans , Immunohistochemistry , Leiomyoma/chemistry , Leiomyoma/ultrastructure , Lipoma/chemistry , Lipoma/ultrastructure , Microscopy, Electron , Middle Aged , Muscle, Smooth/chemistry , Muscle, Smooth/pathology , Muscle, Smooth/ultrastructure , Soft Tissue Neoplasms/chemistry , Soft Tissue Neoplasms/ultrastructureABSTRACT
While the reduction in maternal and perinatal mortality remains a constant goal, the emphasis in modern obstetrics has shifted towards the assessment of foetal welfare in utero. However, if the clinician is to avoid ultimate confusion, he must temper the information which may be obtained from the numerous tests and techniques available with shrewd clinical judgement. In addition, in the current climate of economic audit, he must consider the cost of the investigations in pure monetary terms.
Subject(s)
Prenatal Diagnosis/methods , Amniocentesis , Estriol/urine , Female , Fetal Monitoring , Fetoscopy , Fetus/diagnostic imaging , Gestational Age , Humans , Infant, Newborn , Pregnancy , Pregnancy Complications , Radiography , UltrasonographyABSTRACT
A study of children whose birth weights or placental weights were above the 90th or below the 10th percentile for gestational age indicated that bigness at birth tends to be an innate quality, as the majority of those who were large at birth remained oversized. The small at birth are not all destined to remain diminutive, as the children in this category attained a normal distribution curve for weight during the first year of life. Thus smallness at birth may represent intrauterine nutritional deprivation and be overcome with normal access to calories. The influence of the placenta on infant size is temporary and is modified by extrauterine nutrition. Thus, although there was a direct relationship between birth weight and placental weight, the distribution of weight of children with either large or small placentas was not significantly different from the expected normal distribution at one year of age.
