Three-Dimensional Bone Block Planning for Mandibular Sagittal Bone Defect Reconstruction.

Bone defects seen in severe sagittal discrepancies between the maxilla and mandible do not solely qualify for orthodontic treatment. An interdisciplinary approach with the aid of a surgical, orthodontic, and periodontal team should be implemented in the treatment of such cases. Despite the use of standard treatment methods, the therapy is always planned and carried out individually for each patient. The surgical treatment of bone defects in the area of the jawbones is associated with a number of potential complications. Regenerative medicine, which has already been practiced in reconstructive surgery, is now gradually receiving more attention in the treatment of orthognathic defects. We developed a method for the reconstruction of the alveolar bone in the sagittal dimension using 3D allogenic graft blocks, as a preparing feature in the orthodontic treatment of borderline cases or as a treatment option for complications arising during general orthodontic treatment.

A new approach to spectroscopic and structural studies of the nano-sized silicate-substituted hydroxyapatite doped with Eu3+ ions.

Nanocrystalline silicate-substituted hydroxyapatites Ca10-xEux(PO4)4(SiO4)2(OH)2 (where x = 0.5, 1.0, 2.0, 5.0 mol%) doped with Eu3+ ions were synthesized using a microwave assisted hydrothermal method and heat-treated in the temperature range from 700 to 1000 °C. The concentration of optically active Eu3+ ions was established in the range of 0.5-5 mol% to investigate the preference of occupancy sites. The structural and morphological properties of the obtained biomaterials were determined by using XRD (X-Ray Powder Diffraction), TEM (Transmission Electron Microscopy) and SEM (Scanning Electron Microscopy) techniques as well as infrared (IR) spectroscopy. The average particle sizes were calculated to be in the range from 20 nm to 80 nm by the Rietveld method. The charge compensation mechanism in europium(iii)-doped silicate-substituted hydroxyapatite was proposed in the Kröger-Vink-notation. The luminescence properties (the emission, excitation spectra and emission kinetics) of the Eu3+ ion-doped apatite were recorded depending on the dopant concentration. The existence of Eu2+ ions was confirmed by the emission spectra.