Changes in the intake of vitamins and minerals by men and women with hyperlipidemia and overweight during dietetic treatment.

OBJECTIVES: To assess the influence of a low-fat, low-energy diet on the intake of vitamins and minerals in patients with overweight and hyperlipidemia. SETTING: Outpatient clinic for hyperlipidemia treatment. SUBJECTS: A total of 134 subjects chosen from patients attending Outpatient Clinic of Metabolic Diseases. INTERVENTIONS: Patients were assigned to a hypolipidemic, low-energy diet of 4.18-6.27 MJ/day (1000 or 1500 kcal/day), where fat provided less than 30% of energy, saturated fatty acids less than 10% of energy and daily supply of cholesterol was below 300 mg. Dietary assessment with the use of 3 days dietary records were performed at baseline and after 8 weeks of the diet. RESULTS: The implementation of a low-fat, low-energy diet resulted in a decrease of the intake of nutrients assessed, statistically significant for phosphorus, magnesium, iron and vitamin B(1), B(2) and niacin in men and for iron in women. No marked and statistically significant reduction in the percentage of the RDA was found, except magnesium, thiamin and riboflavin in men and iron in women. Nutritional density was statistically improved for phosphorus, potassium, magnesium and vitamins E, C and B(6) in men and for all nutrients assessed in women. CONCLUSIONS: In comparison with a habitual diet, the low-fat, low-energy diet did not cause any marked and statistically significant decrease in the intake of minerals and vitamins or in the adherence to the RDA, with the exception of magnesium, thiamin and riboflavin in men and iron in women.

[Risk factors for coronary heart disease in 1002 patients with hyperlipidemia]. / Czynniki ryzyka choroby niedokrwiennej serca u 1002 pacjentów z hiperlipidemia.

The aim of this study was to estimate the coexistence of risk factors for coronary heart disease (CHD) in hyperlipidemic patients. Studies were performed in 1002 (601 women, 401 men) subjects who referred to our outpatient clinic among 12 months. Hypercholesterolemia was the predominant lipid disorder found in 66% of patients, mixed hyperlipidemia in 31.8%, and hypertriglyceridemia only in 2.2%. Overweight and obesity remain a major health burden among our patients: BMI > or = 25 was observed in 66%. Hypertension was recognized in 37.5% of subjects, and diabetes mellitus in 11.2%, 17% were long-term smokers. Familial aggregation of hyperlipidemia was observed in 15.7% of subjects, and more than 44% had a positive family history of cardiovascular disease. Low HDL cholesterol levels (< 35 mg/dl) were seen frequently in men (24.7%) and rare in women (7%). Lp(a) excess (> or = 30 mg/dl) was observed in 12% of patients. Myocardial infarction (MI) had already 11.7% subjects (7% women, 18.7% men). In these patients CHD risk factors were observed more frequently. The higher apo B and Lp(a) levels and lower HDL cholesterol levels were recognized in the patients who suffered from MI. More than 83% of our hyperlipidemic patients had coexistence CHD risk factors. The multiple coexisting risk factors cause the high risk for CHD and they require intensive correction.