[Effect of gravitational tidal changes on the periodicity of T-lymphocyte receptor expression in vitro]. / Vliianie prilivnykh izmenenii sily tiazhesti na periodichnost' ékspressii retseptorov T-limfotsitov in vitro.

The hourly registration of the expression of the human s T-lymphocytes subpopulations receptors in vitro during 6 hours demonstrated the existence of the periodicity from 2 to 4 hours. There is high degree of T-lymphocytes expressions coincidence from different individuals depending of the date. For most of daily average individual chronograms, there were described back linear and valid correlations with a character of heterogeneity of the gravity force changes. The results are in according to suggestion about the time field geometric effect to structural-functional cells periodicity.

[Laser flow cytometry in the diagnosis of chronic hepatitis of different etiologies]. / Lazerno-protochnaia tsitometriia v diagnostike khronicheskikh gepatitov razlichnoi étiologii.

A study was made of the immune status in patients suffering from chronic hepatitis (CH) of viral, alcoholic and toxic etiology. The T-system cellular immunity (OKT-3+, OKT-4+, OKT-8+, OKT-11+) was subjected to a subpopulation analysis using monoclonal antibodies and flow laser cytometry. CH of varying etiology is marked by impairment of the immune status. Especially manifest are suppression of OKT-3(+)-, OKT-4(+)-, OKT-8(+)-positive cells and imbalance of OKT-4+ and OKT-8+, with the changes revealed being dependent on the etiological pattern of CH. The data obtained point to the development of secondary immunodeficiency of the T-cell component at the level of different T lymphocyte subpopulations, which depends on the clinico-morphological and etiological pattern of CH. The revealed changes in the immune system may serve as a criterion for differential diagnosis and elaboration of efficient immunocorrective therapy of CH.