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Klin Lab Diagn ; (4): 12-4, 2008 Apr.
Article in Russian | MEDLINE | ID: mdl-18619200

ABSTRACT

The kinetics of a spontaneous peripheral blood neutrophilic nitroblue tetrazolium test (NBT-test) has been studied in neonatal infants. The reaction is shown to come to an end after 60-min reaction mixture thermostating, thereafter the proportion of activated neutrophils (PAN) does not change (PAN(infinity)). The reaction is described using the first-order kinetic equation that is similar to that having the rate constant k1. The calculations of PAN(infinity) and k1 allow a differential diagnosis of bacterial infections with and/or without pneumonia.


Subject(s)
Infant, Newborn, Diseases/diagnosis , Neutrophil Activation , Neutrophils , Nitroblue Tetrazolium/chemistry , Pneumonia, Bacterial/diagnosis , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases/immunology , Male , Neutrophil Activation/immunology , Neutrophils/immunology , Pneumonia, Bacterial/immunology
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