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J Gynecol Obstet Biol Reprod (Paris) ; 39(3): 218-23, 2010 May.
Article in French | MEDLINE | ID: mdl-20338695

ABSTRACT

OBJECTIVES: To evaluate the efficiency of blood tests (blood group, direct antiglobulin test) to assess severe hyperbilirubinemia in full-term newborns, delivered from mothers with rhesus negative or O group and to determine clinical and biological factors that may improve the prediction characteristics of this blood test. PATIENTS AND METHODS: We included all the full-term newborns, delivered from mothers with rhesus negative or O group, in a tertiary maternity ward, in 2005, from January6th to December31st. RESULTS: One thousand and ninety-two children were included. Newborns of A, B or AB group delivered from a mother 0 were at increased risk of presenting severe hyperbilirubinemia (OR=2.35 [1.22-4.52]). The negative predictive value was 96%. Yet, the determination of the Coombs test does not increase NPV. CONCLUSION: Systematic performance of blood test for newborns delivered from mother with O group does increase the ability to predict severe hyperbilirubinemia in a newborn infant. Direct antiglobulin test systematic performance remains questionable.


Subject(s)
Blood Group Incompatibility/blood , Blood Grouping and Crossmatching , Coombs Test , Hyperbilirubinemia/blood , ABO Blood-Group System/immunology , Female , Gestational Age , Humans , Hyperbilirubinemia/etiology , Hyperbilirubinemia/therapy , Infant, Newborn , Length of Stay , Male , Patient Discharge , Phototherapy , Pregnancy , Rh Isoimmunization/blood , Rh-Hr Blood-Group System/immunology , Sensitivity and Specificity
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