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Bioorg Med Chem Lett
; 9(12): 1683-6, 1999 Jun 21.
Article
in English
| MEDLINE
| ID: mdl-10397501
ABSTRACT
5-Deoxy-D-xylofuranose derivatives and a range of new 5,6-dideoxy analogs of D-glucofuranose bearing azido or fluoro substituents were synthesised and employed as substrates of the NADH-dependent aldehyde reduction catalysed by yeast aldose reductase. In terms of catalytic efficiencies, these products proved to be superior to the parent compounds.