ABSTRACT
Paragangliomas are rare, benign and slow-growing neuroendocrine tumors that can arise from the adrenal medulla (8590%) or from the extra-adrenal paraganglia. In the central nervous system (CNS), they can be found at several sites, but more often at the cauda equina and filum terminale region, where they account for between 2.5 and 3.8% of total tumor cases of that region. There are only 8 cases described in the literature that mention the presence of the gangliocytic variant of this entity at the filum terminale. We present the case of a 41-year-old man with chronic lumbar pain refractory to medical treatment, without any associated neurological deficits. Magnetic resonance imaging (MRI) revealed an intradural, extramedullar oval lesion with regular contours and homogeneous caption of contrast at L1 level. He was submitted to surgical treatment, with complete resection of the lesion. The histological analysis revealed a gangliocytic paraganglioma of the filum terminale. At 5 years of follow-up, he remains asymptomatic and without any signs of relapse. These are lesions with an overall good prognosis with gross total resection. Although the recurrence rate is extremely low, prolonged observation is recommended due to the slow-growing nature of the tumor, being estimated that between 1 and 4% can recur even after gross total removal.
Subject(s)
Humans , Male , Adult , Paraganglioma/surgery , Paraganglioma/pathology , Peripheral Nervous System Neoplasms/surgery , Cauda Equina/surgery , Paraganglioma/diagnostic imaging , Peripheral Nervous System Neoplasms/diagnostic imaging , Cauda Equina/injuries , Low Back Pain , Laminectomy/methodsABSTRACT
Resumo Neste artigo teórico, partimos do princípio de que os processos humanos de significação e de conhecimento se consubstanciam e se desenvolvem em interdependência com os outros, para abordarmos a identidade pessoal como um espaço dialógico entre um Eu e um Outro (uma pessoa, um grupo, uma comunidade, uma sociedade), dinamicamente regulado por afetos. A inerência dialógica da vida psicológica é abordada - i.e., o papel dos outros na constituição da subjetividade humana - e, particularmente, as dimensões afetivas e motivacionais desse processo.
Abstract In this theoretical paper we assume that human processes of meaning-making and knowledge are embodied and developed in interdependence with the Other(s) in order to approach personal identity as a dialogical space between the I and the Other (an I-position, a person, a group, a community, a society) dynamically regulated by affection. The dialogical inherence of psychological life is addressed, i.e., the role of otherness in the constitution of human subjectivity and particularly the affective and motivational dimensions of this process.