ABSTRACT
A cross-sectional study was conducted in a university hospital, enrolling 40 patients with pre-eclampsia (case group) and 40 healthy normotensive pregnant women (control group). Plasma activity of antioxidants and some adhesion molecules involved in oxidative stress were measured and compared between the two groups, according to the patients' age. In patients over the age of 30 years, serum levels of L-selectin and E-selectin were lower in pre-eclamptic patients (p < 0.05); antioxidants, catalase and superoxide dismutase did not significantly differ between the two groups, while glutathione peroxidase was significantly higher in the normotensive group (p < 0.05). In patients under the age of 30 years, E-selectin was significantly higher in the pre-eclampsia group (p < 0.05), while P-selectin, catalase and superoxide dismutase were not significantly different between the two groups (p > 0.05). Total antioxidative activity was similar between pre-eclamptic and normotensive patients (p > 0.05). This study revealed no relationship between total antioxidant activity and pre-eclampsia.
Subject(s)
Catalase/blood , Glutathione/blood , Pre-Eclampsia/blood , Selectins/blood , Superoxide Dismutase/blood , Adult , Antioxidants/metabolism , Case-Control Studies , Cross-Sectional Studies , Female , Humans , Pregnancy , Young AdultABSTRACT
To evaluate the beliefs and practices of patients diagnosed with asthma about various aspects of their condition we interviewed 123 patients attending 2 outpatient departments of hospitals in Tehran. Most of the participants did not recall their past medical history of asthma. Many patients with a history of using oral inhalers did not use these regularly (41.9%); the major reason reported was feeling no need to use medication during symptom-free intervals. Only 32 (30.5%) patients demonstrated the correct technique for using their oral inhaler. Patients with asthma need more education about prevention and control of symptoms. Neglect by physicians of the Global Initiative for Asthma management guidelines was another major concern.
Subject(s)
Asthma , Health Knowledge, Attitudes, Practice , Medication Adherence , Outpatients , Patient Education as Topic , Self Care , Administration, Inhalation , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Asthmatic Agents/therapeutic use , Asthma/prevention & control , Asthma/psychology , Female , Health Services Needs and Demand , Hospitals, Urban , Humans , Iran , Male , Medication Adherence/psychology , Medication Adherence/statistics & numerical data , Middle Aged , Nebulizers and Vaporizers , Outpatients/education , Outpatients/psychology , Self Care/methods , Self Care/psychology , Self Care/statistics & numerical data , Surveys and QuestionnairesABSTRACT
To evaluate the beliefs and practices of patients diagnosed with asthma about various aspects of their condition we interviewed 123 patients attending 2 outpatient departments of hospitals in Tehran. Most of the participants did not recall their past medical history of asthma. Many patients with a history of using oral inhalers did not use these regularly [41.9%]; the major reason reported was feeling no need to use medication during symptom-free intervals. Only 32 [30.5%] patients demonstrated the correct technique for using their oral inhaler. Patients with asthma need more education about prevention and control of symptoms. Neglect by physicians of the Global Initiative for Asthma management guidelines was another major concern
